Explore Southwest Illinois Spa Hotels & Wellness Resorts

Start date: Check-in selected.
To Date
End date: Check-out

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Top Southwest Illinois Spa Resorts & Hotels

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3 out of 5
145 North 44th Street , Mount Vernon, IL
Free Cancellation
Reserve now, pay when you stay
$94 nightly
The price is $106 total per night
$106 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

3 out of 5
1118 Central Park Drive, O'Fallon, IL
Free Cancellation
Reserve now, pay when you stay
$102 nightly
The price is $118 total per night
$118 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Drury Inn & Suites Marion

Drury Inn & Suites Marion

3 out of 5
2706 W DeYoung St, Marion, IL
Free Cancellation
Reserve now, pay when you stay
$65 nightly
The price is $78 total per night
$78 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Marion I-57

2.5 out of 5
2403 Black Diamond Dr, Marion, IL
Free Cancellation
Reserve now, pay when you stay
$108 nightly
The price is $130 total per night
$130 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

3 out of 5
12 Ludwig Dr, Fairview Heights, IL
Free Cancellation
Reserve now, pay when you stay
$93 nightly
The price is $106 total per night
$106 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

2.5 out of 5
404 South 44th Street, Mount Vernon, IL
Free Cancellation
Reserve now, pay when you stay
$109 nightly
The price is $123 total per night
$123 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Best Western Marion Hotel

Best Western Marion Hotel

2.5 out of 5
400 Comfort Dr, Marion, IL
Free Cancellation
Reserve now, pay when you stay
$80 nightly
The price is $96 total per night
$96 total
Oct 6 - Oct 7
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Quality Inn O'Fallon IL - St. Louis

Quality Inn O'Fallon IL - St. Louis

3 out of 5
1409 W US 50, O'Fallon, IL
Free Cancellation
Reserve now, pay when you stay
$63 nightly
The price is $72 total per night
$72 total
Oct 28 - Oct 29
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Americas Best Value Inn Mount Vernon

Americas Best Value Inn Mount Vernon

2.5 out of 5
222 South 44th Street, Mount Vernon, IL
Free Cancellation
Reserve now, pay when you stay
$64 nightly
The price is $72 total per night
$72 total
Sep 30 - Oct 1
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like continental breakfast and WiFi ...
Days Inn by Wyndham Pontoon Beach

Days Inn by Wyndham Pontoon Beach

2 out of 5
5105 Highway 111, Granite City, IL
Free Cancellation
Reserve now, pay when you stay
$60 nightly
The price is $66 total per night
$66 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate freebies like continental ...
Econo Lodge

Econo Lodge

2 out of 5
1806 Bittle Place, Marion, IL
Free Cancellation
Reserve now, pay when you stay
$64 nightly
The price is $77 total per night
$77 total
Sep 30 - Oct 1
Total with taxes and fees
A casino and an indoor pool are featured at this hotel. Business travelers can take advantage of the free WiFi in public areas. Enjoy the gym and free perks ...
Days Inn & Suites by Wyndham Caseyville

Days Inn & Suites by Wyndham Caseyville

2.5 out of 5
2423 Old Country Inn Drive, Caseyville, IL
Free Cancellation
Reserve now, pay when you stay
$53 nightly
The price is $60 total per night
$60 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Don't see what you're looking for?
See all available properties in Southwest Illinois
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Southwest Illinois Spa Hotels

Are you looking for a break from the hustle and bustle of your day-to-day life? Do you want to escape reality and forget about your never ending to-do list? Then why not treat yourself to a relaxing stay at one of the spa hotels in Southwest Illinois? Whether it is for a weekend getaway or a staycation, book your visit to one of the Southwest Illinois luxury spa hotels.

With all of the amazing things to do around Southwest Illinois, you will likely be worn out from sightseeing. The Southwest Illinois spa hotels provide top of the line facilities with hot-tubs, saunas and private treatment rooms. Treat yourself to an indulgent hot stone massage or facial to rejuvenate from a busy day. If that's not enough for you, indulge in a full day-at-the-spa package. And maybe you are just looking to reach maximum relaxation before a fancy night out on the town. Take advantage of the salon features offered at most Southwest Illinois spa hotels and get a mani-pedi before your evening begins. 

Travelocity wants to help you relax and rejuvenate during your next stay in Southwest Illinois, but we know that spa treatments can put some strain on your wallet. Bundle your hotel and flight together and save enough to pay for your facial!

Southwest Illinois hotels essential information

Accommodation
713 hotels
Lowest Price
$60
Highest Price
$130
Popular hotels
Drury Inn & Suites St. Louis Fairview Heights, Drury Inn & Suites Marion, Comfort Suites Mount Vernon, Quality Inn O'Fallon IL - St. Louis, Days Inn by Wyndham Pontoon Beach, Days Inn & Suites by Wyndham Caseyville, Americas Best Value Inn Mount Vernon, Best Western Marion Hotel, Comfort Inn & Suites Marion I-57, Drury Plaza Hotel Mt. Vernon, Drury Inn & Suites St. Louis O'Fallon, IL, Econo Lodge

Recent Southwest Illinois hotel reviews by fellow wanderers

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Lady at the front desk at check in was very kind and polite. "
A verified traveler from speedwell stayed at Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. Vernon