Book Hotels in Santa Cruz Tlaxcala

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Santa Cruz Tlaxcala hotels

Pietro Santo

Pietro Santo

2 out of 5
Sta Isa Tetlahuaca Km2 San Miguel Xoxtla Santeagueda TLAX
$82 nightly
The price is $97 total per night from Dec 13 to Dec 14
$97 total
Dec 13 - Dec 14
Total with taxes and fees
Luggage storage is provided and the front desk is staffed around-the-clock.
"Easy to book, clean n cozy place!"

Reviewed on Nov 4, 2026

Opens in a new windowPietro Santo
Fiesta Inn Express Puebla Finsa

Fiesta Inn Express Puebla Finsa

3.5 out of 5
Rancho Moratilla 7735 Puebla PUE
$68 nightly
The price is $80 total per night from Dec 14 to Dec 15
$80 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
"The staff it’s amazing, kind and helpful. The hotel is okay, perfect to stay a couple days. Parking right there and the breakfast amazing"

Reviewed on Oct 13, 2026

Opens in a new windowFiesta Inn Express Puebla Finsa
Marriott Puebla Hotel Meson del Angel

Marriott Puebla Hotel Meson del Angel

4.5 out of 5
Avenida Hermanos Serdan 807 Puebla PUE
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $65 total per night from Dec 4 to Dec 5
$65 total
Dec 4 - Dec 5
Total with taxes and fees
This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
"Nice hotel Location is great"

Reviewed on Nov 10, 2026

Opens in a new windowMarriott Puebla Hotel Meson del Angel
Centro Vacacional La Trinidad

Centro Vacacional La Trinidad

2.5 out of 5
s/n Del Trabajo Santa Cruz Tlaxcala TLAX
$58 nightly
The price is $69 total per night from Dec 8 to Dec 9
$69 total
Dec 8 - Dec 9
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 3 outdoor pools, and 2 outdoor tennis courts. Enjoy the indoor pool and perks like free self parking. A garden ...
"Overall, the property is old, the room was little bit dirty, front desk very rude, the rest were very kind."

Reviewed on Apr 28, 2026

Opens in a new windowCentro Vacacional La Trinidad
Fiesta Inn Parque Puebla

Fiesta Inn Parque Puebla

3.5 out of 5
Calzada Ignacio Zaragoza, Número 410 Puebla PUE
$72 nightly
The price is $86 total per night from Dec 14 to Dec 15
$86 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowFiesta Inn Parque Puebla
Holiday Inn Puebla Finsa by IHG

Holiday Inn Puebla Finsa by IHG

4 out of 5
Lateral Mexico - Puebla: 7719 Puebla PUE
Fully refundable
$58 nightly
The price is $69 total per night from Nov 26 to Nov 27
$69 total
Nov 26 - Nov 27
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center ...
Opens in a new windowHoliday Inn Puebla Finsa by IHG
NH Puebla Finsa

NH Puebla Finsa

3.5 out of 5
Av. Moratilla 132-1 Puebla PUE
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $69 total per night from Nov 29 to Nov 30
$69 total
Nov 29 - Nov 30
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Opens in a new windowNH Puebla Finsa
Hotel San Francisco Tlaxcala

Hotel San Francisco Tlaxcala

3.5 out of 5
Plaza de la Constitución 17 Tlaxcala TLAX
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $87 total per night from Dec 6 to Dec 7
$87 total
Dec 6 - Dec 7
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and an outdoor pool. Relax with a drink at the poolside bar and enjoy free perks like buffet breakfast ...
Opens in a new windowHotel San Francisco Tlaxcala
Ramada Encore by Wyndham Puebla

Ramada Encore by Wyndham Puebla

4 out of 5
Lateral del Anillo Periferico Coronango PUE
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $73 total per night from Nov 24 to Nov 25
$73 total
Nov 24 - Nov 25
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowRamada Encore by Wyndham Puebla
Don't see what you're looking for?
See all available properties in Santa Cruz Tlaxcala
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Santa Cruz Tlaxcala?
Take some of the troubles out of traveling with little ones by opting for a family-friendly hotel in Santa Cruz Tlaxcala. From well-thought-out amenities to additional services, these stays feature perks that'll make your getaway run smoothly: Rest home to celebrate life! will help make your break the most memorable one yet. It features lots of nice little touches, such as pet-friendly facilities and free WiFi. Alternatively, spend your Santa Cruz Tlaxcala break at El Sabinal Hotel Boutique. Take advantage of a swimming pool, a cafe and more here.
Where can I find cheap hotels in Santa Cruz Tlaxcala?
At Travelocity you'll find really nice hotels in Santa Cruz Tlaxcala at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Santa Cruz Tlaxcala rather than in Santa Cruz Tlaxcala. We may find you even better rates, too.
How do I find the best Santa Cruz Tlaxcala hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Santa Cruz Tlaxcala then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Santa Cruz Tlaxcala?
The cheapest hotel in Santa Cruz Tlaxcala is $65. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Santa Cruz Tlaxcala?
There are 258 hotels in Santa Cruz Tlaxcala on Travelocity.
What are the best hotels in Santa Cruz Tlaxcala?
Santa Cruz Tlaxcala has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Santa Cruz Tlaxcala for you!
When is the best time to visit Santa Cruz Tlaxcala?
If you want the joy of a fun-filled trip in peak season, visit Santa Cruz Tlaxcala during March, August and October. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, May and June.
When is the cheapest time to stay in Santa Cruz Tlaxcala?
Based on historic data is usually the cheapest month to visit Santa Cruz Tlaxcala. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Santa Cruz Tlaxcala?
There are multiple hotels in Santa Cruz Tlaxcala that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Santa Cruz Tlaxcala. We have plenty of kid-friendly hotels in Santa Cruz Tlaxcala to choose from on Travelocity!
Why book a hotel in Santa Cruz Tlaxcala through Travelocity?
Because we have the top hotels in Santa Cruz Tlaxcala! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Santa Cruz Tlaxcala on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Santa Cruz Tlaxcala hotel reviews by fellow wanderers

Villa Toscana ValQuirico Hotel Boutique

Villa Toscana ValQuirico Hotel Boutique

5 out of 5
Posted 6 hours ago
Travelocity Verified Review
"Perfect stay for my wife and her mom!"
A verified traveler stayed at Villa Toscana ValQuirico Hotel Boutique
Villa Toscana ValQuirico Hotel Boutique

Explore More Ways to Travel with Travelocity