Book Hotels in Santa Cruz

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Santa Cruz hotels

Hotel Boutique Grand Cru

Hotel Boutique Grand Cru

3 out of 5
Chomedahue, cruce El Guindo Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $91 total per night from Nov 29 to Nov 30
$91 total
Nov 29 - Nov 30
This hotel features an outdoor pool and a gym. Enjoy the steam room and free perks like continental breakfast and free self parking. A business center, free ...
"Great breakfast. Super host Juan Luis. Great location. Comfy bed. Spacious loft style rooms"

Reviewed on Mar 29, 2026

Opens in a new windowHotel Boutique Grand Cru
Hotel Vendimia Parador

Hotel Vendimia Parador

3 out of 5
Camino Los Boldos SN Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
$49 nightly
The price is $49 total per night from Nov 22 to Nov 23
$49 total
Nov 22 - Nov 23
This hotel features an outdoor pool and an indoor pool. Relax with a drink at the swim-up bar and enjoy perks like free self parking and free WiFi. Free parking, ...
"Our stay was wonderful. The property was surrounded with beautiful sights from fascinating antiques to the lush gardens. The owners were very attentive and always available for whatever we needed or had questions about. The breakfast was delicious and elegant. Cannot say enough about our stay. Everything ..."

Reviewed on Oct 20, 2026

Opens in a new windowHotel Vendimia Parador
TerraViña

TerraViña

3 out of 5
Camino Los Boldos S/n Santa Cruz O'Higgins
$180 nightly
The price is $180 total per night from Nov 1 to Nov 2
$180 total
Nov 1 - Nov 2
An attached winery and a restaurant are featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public ...
"The staff were very friendly and knowledgeable of the local restaurants and wineries. The room has a balcony which was fabulous. Properly was well maintained and beautiful. Definitely would come back to this property."

Reviewed on Aug 7, 2026

Opens in a new windowTerraViña
Hotel Cava Colchagua

Hotel Cava Colchagua

4 out of 5
Barreales´s Way Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $134 total per night from Nov 18 to Nov 19
$134 total
Nov 18 - Nov 19
This hotel features an attached winery, a full-service spa, and a restaurant. Enjoy the outdoor pool and free perks like local cuisine breakfast and WiFi in ...
"Excelente y original experiencia boutique Una propuesta realmente innovadora. Se trata de un hotel boutique hermoso cuyas habitaciones están acondicionadas dentro de barricas de roble, muy bien adaptadas y acogedoras. Como sugerencia de mejora, creo que a las habitaciones más grandes les vendría ..."

Reviewed on Aug 7, 2026

Opens in a new windowHotel Cava Colchagua
Santa Cruz Plaza

Santa Cruz Plaza

4 out of 5
Plaza De Armas 286 Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $119 total per night from Nov 8 to Nov 9
$119 total
Nov 8 - Nov 9
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Families will appreciate the free kid's club, barbecue grills, ...
"Unfortunately our room faced the plaza and loud band until almost midnight! Also at 3 am we were awakened by loud tapping noise that lasted about 20 minutes"

Reviewed on Oct 18, 2026

Opens in a new windowSanta Cruz Plaza
Hotel Boutique Vendimia Premium

Hotel Boutique Vendimia Premium

3.5 out of 5
Ismael Valdes 92 Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $62 total per night from Nov 1 to Nov 2
$62 total
Nov 1 - Nov 2
A seasonal outdoor pool, free self parking, and free newspapers are featured at this hotel. WiFi in public areas is free. A terrace, a garden, and a lobby fireplace ...
Opens in a new windowHotel Boutique Vendimia Premium
La Perla Hotel

La Perla Hotel

3.5 out of 5
El Rosal, Parcela 4, Lote A, Capellanía Santa Cruz O'Higgins
$139 nightly
The price is $139 total per night from Oct 30 to Oct 31
$139 total
Oct 30 - Oct 31
This hotel features a seasonal outdoor pool and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, and airport ...
Opens in a new windowLa Perla Hotel
Colchagua Tiny Lodge

Colchagua Tiny Lodge

3.5 out of 5
I-350 kilometro 4,5 Santa Cruz O'Higgins
$182 nightly
The price is $182 total per night from Nov 6 to Nov 7
$182 total
Nov 6 - Nov 7
This cabin features free WiFi in public areas, barbecue grills, and free self parking. Enjoy the free local cuisine breakfast each morning. A terrace, a garden, ...
Opens in a new windowColchagua Tiny Lodge
Casa Calfu

Casa Calfu

3 out of 5
21 de Mayo 552 Santa Cruz OHiggins
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $82 total per night from Nov 1 to Nov 2
$82 total
Nov 1 - Nov 2
An outdoor pool, free self parking, and laundry facilities are featured at this bed & breakfast. Guests will appreciate free perks like buffet breakfast and ...
Opens in a new windowCasa Calfu
Don't see what you're looking for?
See all available properties in Santa Cruz
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Santa Cruz?
Family trips are where wonderful memories are made, but traveling with children can be a challenge. These kid-friendly Santa Cruz hotels offer perks designed to keep young and old alike relaxed and happy: Put your bags down at Santa Cruz Plaza. It comes with childcare services, a swimming pool and a commitment to making families feel welcome. Intown Apart Santa Cruz is another top place to stay. After a fun day of sightseeing, return to your comfortable room and perks like free WiFi and extra bedding.
Where can I find cheap hotels in Santa Cruz?
At Travelocity you'll find really nice hotels in Santa Cruz at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Santa Cruz rather than in Santa Cruz. We may find you even better rates, too.
How do I find the best Santa Cruz hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Santa Cruz then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Santa Cruz?
The cheapest hotel in Santa Cruz is $49. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Santa Cruz?
There are 62 hotels in Santa Cruz on Travelocity.
What are the best hotels in Santa Cruz?
Santa Cruz has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Santa Cruz for you!
When is the best time to visit Santa Cruz?
If you want the joy of a fun-filled trip in peak season, visit Santa Cruz during August, September and October. If you'd prefer the peace of off-season, book a stay during quieter months, such as February, March and November.
When is the cheapest time to stay in Santa Cruz?
Based on historic data is usually the cheapest month to visit Santa Cruz. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Santa Cruz?
There are multiple hotels in Santa Cruz that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Santa Cruz. We have plenty of kid-friendly hotels in Santa Cruz to choose from on Travelocity!
Why book a hotel in Santa Cruz through Travelocity?
Because we have the top hotels in Santa Cruz! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Santa Cruz on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Santa Cruz hotel reviews by fellow wanderers

Hotel Vendimia Parador

Hotel Vendimia Parador

5 out of 5
Posted 9 days ago
Travelocity Verified Review
"Our stay was wonderful. The property was surrounded with beautiful sights from fascinating antiques to the lush gardens. The owners were very attentive and always available for whatever we needed or had questions about. The breakfast was delicious and elegant. Cannot say enough about our stay. Everything was perfect. It was located very close to a few dining options and wineries too!"
A verified traveler stayed at Hotel Vendimia Parador
Hotel Vendimia Parador