Deals on vacations and trips to Santa Ana

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Santa Ana flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,185, price is now $829 per person
$829
per person
Oct 7 - Oct 12
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Relax with a drink at the bar/lounge and enjoy the free buffet breakfast each morning.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $2,047, price is now $958 per person
$958
per person
Nov 4 - Nov 9
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Save 100% on your flight
Price was $1,875, price is now $961 per person
$961
per person
Oct 7 - Oct 12
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and free self parking.
Villa Marina Hotel

Villa Marina Hotel

3.5 out of 5
Price was $1,352, price is now $919 per person
$919
per person
Nov 4 - Nov 9
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
This hotel features 2 bars/lounges, a beach bar, and a restaurant. Families will appreciate the onsite laundry facilities, kid-friendly dining, and in-room childcare. Enjoy the outdoor pool and perks like free self parking and free WiFi.
Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Bella Vista
Price was $1,306, price is now $922 per person
$922
per person
Oct 7 - Oct 12
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and airport shuttle. Relax with a drink at one of the 2 bars/lounges and enjoy perks like free valet parking.

Top Santa Ana hotels deals

Hotel Caracas - Casco Viejo

Hotel Caracas - Casco Viejo

3 out of 5
Plaza De Santa Ana Panama City Provincia di Panama
Free Cancellation
Reserve now, pay when you stay
$36 nightly
The price is $40 total per night
$40 total
Sep 15 - Sep 16
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. A coffee shop and a snack bar/deli are also provided.
Free WiFi
Restaurant
Casco View Apartments

Casco View Apartments

3.5 out of 5
C. 16 Oeste Panama City Provincia de Panamá
$83 nightly
The price is $92 total per night
$92 total
Sep 8 - Sep 9
Total with taxes and fees
An outdoor pool is featured at this condo, along with a terrace and a garden. Staff at the 24-hour front desk can provide around-the-clock assistance.
Pool
Kitchen
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Free Cancellation
Reserve now, pay when you stay
$123 nightly
The price is $135 total per night
$135 total
Sep 28 - Sep 29
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Relax with a drink at the bar/lounge and enjoy the free buffet breakfast each morning.
Pool
Breakfast included
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Plaza de la Independencia Casco Viejo Panama City Panama
Free Cancellation
Reserve now, pay when you stay
$183 nightly
The price is $202 total per night
$202 total
Oct 2 - Oct 3
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.
Pool
Spa
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Free Cancellation
$136 nightly
The price is $150 total per night
$150 total
Oct 4 - Oct 5
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool, onsite laundry facilities, and babysitting. Enjoy the 24-hour gym and perks like free WiFi and a free airport shuttle.
Pool
Free airport shuttle
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
Free Cancellation
Reserve now, pay when you stay
$278 nightly
The price is $278 total per night
$278 total
Oct 1 - Oct 2
Total with taxes and fees
This all-inclusive property features a full-service spa, a nightclub, and 7 restaurants. Spend a day at the beach kayaking, or relax with free beach cabanas and sun loungers. There's fun for all ages with a free kid's club and mini golf, and in-room childcare is an added bonus.
Pool
Breakfast included
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santa Ana attractions

El Machetazo Santa Ana

You can search for that perfect souvenir at El Machetazo Santa Ana during your trip to Panama City. Amble around the area's parks or visit its shops.
See properties

Frequently asked questions

How much are vacation packages to Santa Ana?
Epic adventures await in Santa Ana, with Travelocity vacation packages starting from just $829. Including both flights and hotels, these sensational deals make it a cinch to discover all corners of the globe.
Where can I get the best vacation package deals for Santa Ana?
Head straight to Travelocity. With access to 400 air carriers and a whopping 1,000,000 properties across the globe, creating the ultimate Santa Ana package deal couldn't be easier.
Why should I purchase my Santa Ana vacation package with Travelocity?
Incredible savings, countless exciting destinations and 24/7 customer service you can rely on — that's why. And with our Price Match Guarantee, you can rest assured knowing that you'll always get the best possible deal with Travelocity.
Can I save money on my Santa Ana car rental if I bundle it with my hotel or flight?
Booking a Santa Ana vacation package with Travelocity is one of the simplest ways to save you time and money. You can choose a car, flight and hotel, or any combination of them, and land awesome discounts. You might also like to throw in a few activities and experiences. Once you've picked up the keys to your rental car, venture out of the neighborhood and see what the surrounding area has to offer. About 35 mi from Santa Ana, Gatun Locks is the perfect road trip.

Photos of local treasures

Browse Santa Ana vacation photos for more inspiration

A gazebo with columns, a large tree with hanging roots, and a building in the background.
A waterfront cityscape with numerous boats docked along the shore and a clear sky.