Deals on vacations and trips to Eastern Panama

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Price found within the past 48 hours. Click for updated prices.
Mahogany Suites

Mahogany Suites

2 out of 5
Price was $878, price is now $578 per person
$578
per person
May 28 - May 31
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
A golf course and an outdoor pool are featured at this hotel. A garden is also provided.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $2,122, price is now $1,319 per person
$1,319
per person
Apr 26 - May 3
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,301, price is now $879 per person
$879
per person
Apr 26 - May 3
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Relax with a drink at the bar/lounge and enjoy the free buffet breakfast each morning.
Yoo by Wynwood House

Yoo by Wynwood House

4 out of 5
Calidonia
Save 100% on your flight
Price was $1,785, price is now $1,272 per person
$1,272
per person
Apr 26 - May 3
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
This condo features an outdoor pool and a gym. Staff at the 24-hour front desk can provide around-the-clock assistance.
Playa Caracol

Playa Caracol

3.5 out of 5
Save 100% on your flight
Price was $1,456, price is now $1,046 per person
$1,046
per person
May 30 - Jun 6
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
A private beach, 2 restaurants, and 3 outdoor pools are all featured at this smoke-free villa. Relax with beach umbrellas and enjoy a refreshing drink at one of the 2 beach bars. Enjoy the 2 outdoor tennis courts and get free self parking.

Top Eastern Panama hotels deals

HOTEL ISLA GRANDE

HOTEL ISLA GRANDE

3 out of 5
Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
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This hotel features a restaurant, a bar/lounge, and a beach bar. If you want to take your pet along, this pet-friendly property offers everything you'll need for your pet including food and water bowls. Free WiFi in public areas is also provided.
Breakfast included
Spa
Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island

2 out of 5
Diablo Island Narganá Guna Yala
Get rates
This hotel features a restaurant, a garden, and a snack bar/deli. Enjoy the free local cuisine breakfast each morning.
Breakfast included
Restaurant
Hotel Cocotal

Hotel Cocotal

2.5 out of 5
La Guaira Isla Grande Provincia de Colón
$99 nightly
The price is $109 total per night
$109 total
Apr 13 - Apr 14
Total with taxes and fees
This smoke-free hotel features 20 restaurants and 20 bars/lounges. Enjoy a meal in one of the 19 coffee shops/cafes and free perks like cooked-to-order breakfast and WiFi in public areas. Wedding services are provided for your convenience.
Breakfast included
Pet friendly
Konsenda San Blas

Konsenda San Blas

2 out of 5
Llano Cartí Km 11 El Llano Panamá Province
Free Cancellation
Reserve now, pay when you stay
Get rates
A restaurant and a bar/lounge are featured at this hotel. Guests will appreciate freebies like continental breakfast and free self parking. A coffee shop, a terrace, and a garden are also on offer.
Breakfast included
Parking included
Ordovician Beach Resort

Ordovician Beach Resort

4.5 out of 5
Isla Grande Isla Grande Colon
$455 nightly
The price is $505 total per night
$505 total
Mar 29 - Mar 30
Total with taxes and fees
This smoke-free resort features a private beach, a full-service spa, and 2 restaurants. Relax with free beach cabanas, sun loungers, and beach umbrellas. Relax with a drink at one of the 2 bars/lounges and enjoy free perks like full breakfast and free self parking.
On private beach
Pool
Ciel y Miel

Ciel y Miel

3 out of 5
Caillle Principale Cacique Provincia de Colón
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A full-service spa, 3 restaurants, and 4 outdoor pools are all featured at this smoke-free hotel. Relax with a drink at the beach bar and enjoy free perks like cooked-to-order breakfast and valet parking. A business center, free WiFi in public areas, and a terrace are also on offer.
Pool
Breakfast included
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Secluded island in the Guna Yala region of Panama

Isla Diablo

Commune with nature and explore the great outdoors at Isla Diablo during your travels in San Blas Islands. Take in the festivals while you're in the area.

Isla Diablo

Isla Chichime

Commune with nature and explore the great outdoors at Isla Chichime during your travels in San Blas Islands. Take in the festivals while you're in the area.

Isla Chichime

Museum of the Kuna Nation

You can spend an afternoon studying the exhibits at Museum of the Kuna Nation in Narganá. Stroll along the seaside or experience the area's festivals.

Museum of the Kuna Nation

Frequently asked questions

How much are vacation packages to Eastern Panama?
Exciting adventures await in Eastern Panama, with Travelocity vacation packages starting from as low as $578. Including flights and hotels, these awesome deals make it a breeze to see more of our beautiful planet.
Where can I get the best vacation package deals for Eastern Panama?
You can snap up amazing Eastern Panama package deals with Travelocity. Mix and match from 400 air carriers and 1,000,000 worldwide properties and turn those travel dreams into a reality.
Why should I purchase my Eastern Panama vacation package with Travelocity?
We offer 24/7 support, top-quality service and a Price Match Guarantee. Life's a great big journey — and we have alluring destinations for you to journey to all across the world. Wander with us and your wallet will thank you for it.
Can I save money on my Eastern Panama car rental if I bundle it with my hotel or flight?
Certainly. And our Eastern Panama vacation packages are the perfect way to do it. In just a few clicks you can save cash as well as time by bundling your bookings. Pick up the keys to your rental car and feel the freedom of the open road. Searching for things to do? Add some tours or experiences to your package and make savings on those too.
What is there to do in Eastern Panama?
You'll be happy to know Eastern Panama is brimming with incredible things to see and do, however Isla Mamey and Cayos Holandeses are right up there with the very best.

Photos of local treasures

Browse Eastern Panama vacation photos for more inspiration

50 Shades of blue. Sailing through the San Blas Islands in Panama lets you experience a pure paradise and crystal clear water. You can buy fresh fish and other seefood drirectly from local fishermen. If you want you can also play Robinson Crusoe on islands with literally only one palm tree. #BVSBlue
A Kuna Yala man headed out to fish. If you have ever dreamed of spending a night or two on a small, private island, check out Kuna Yala. If you don't like roughing it a little bit, this might not be for you. There are cabins with flushing toilets but no electricity and the shower water is rather cool. Great place to get away from crowds and unplug though. #islands #peaceful #Adventure #water #ocean #boat #trovember
A definite bucketlist place to visit if ever in #Panama. #SanBlas
Secluded island in the Guna Yala region of Panama
One of the 365 islands that represent San Blas in Panama. The majority of these islands are inhabited, some of them has the size of various football fields, while others are only a few square meters with one or two palm trees on it.