Book Hotels in Eastern Panama
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Top Eastern Panama hotels
Ciel y Miel
Caillle Principale Cacique Provincia de Colón
$207 nightly
The price is $228 total per night from May 5 to May 6
$228 total
May 5 - May 6
Total with taxes and fees
A full-service spa, 3 restaurants, and 4 outdoor pools are all featured at this smoke-free hotel. Relax with a drink at the beach bar and enjoy free perks like ...
The views from this mountain-top boutique hotel are extraordinary.
Reviewed on Feb 1, 2026
Private Ocean-Front Cabin with private bathroom on San Blas Island
Diablo Island Narganá Guna Yala
This hotel features a restaurant, a garden, and a snack bar/deli. Enjoy the free local cuisine breakfast each morning.
Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door.
Reviewed on Mar 15, 2026
Ordovician Beach Resort
Isla Grande Isla Grande Colon
$481 nightly
The price is $533 total per night from May 4 to May 5
$533 total
May 4 - May 5
Total with taxes and fees
This smoke-free resort features a private beach, a full-service spa, and 2 restaurants. Relax with free beach cabanas, sun loungers, and beach umbrellas. Relax ...
The resort was outstanding. It exceeded expectations in every way. The service was the best we had in Panama. The cocktails were fun and the food was delicious and they have a vegan menu. We stayed in a king room and it was very private, pristine and well appointed.
Reviewed on Feb 21, 2026
Konsenda San Blas
Llano Cartí Km 11 El Llano Panamá Province
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $74 total per night from May 4 to May 5
$74 total
May 4 - May 5
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Guests will appreciate freebies like continental breakfast and free self parking. A coffee shop, a ...
Great location for bird watching! The hosts were friendly and helpful. It is best to contact them directly using WhatsApp in addition to booking on Expedia.
Reviewed on Feb 13, 2026
Private Bedroom on Paradise San Blas Island
Isla Yansailadup Narganá Guna Yala
A beach bar is featured at this guesthouse, along with a picnic area. Enjoy the free continental breakfast each morning. Take advantage of the area shuttle.
Paradise
Don’t go expecting a resort and you will thoroughly enjoy yourself. The Guna that run the island are all warm, friendly, helpful. Great snorkelling tours and beautiful clean water. The accommodations are very simple but comfortable. Shared bathroom that was kept very clean. A great place to get away ...
Reviewed on Jan 13, 2023
HOTEL ISLA GRANDE
Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
$110 nightly
The price is $121 total per night from May 4 to May 5
$121 total
May 4 - May 5
Total with taxes and fees
This hotel features a restaurant, a bar/lounge, and a beach bar. If you want to take your pet along, this pet-friendly property offers everything you'll need ...
Cocoloco - Catamaran Lagoon 52F SAN BLAS
El Porvenir Narganá Guna Yala
Fully refundableReserve now, pay when you stay
$1,974 nightly
The price is $2,178 total per night from May 12 to May 13
$2,178 total
May 12 - May 13
Total with taxes and fees
A restaurant and a bar/lounge are featured at this property. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A coffee ...
San Blas Private Oceanfront Cabin
C5W9 4M Nusatupo Narganá Guna Yala
$359 nightly
The price is $385 total per night from May 5 to May 6
$385 total
May 5 - May 6
Total with taxes and fees
A restaurant is available at this cabin. Enjoy the free continental breakfast each morning. Take advantage of the area shuttle.
Hotel Cocotal
La Guaira Isla Grande Provincia de Colón
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $114 total per night from May 5 to May 6
$114 total
May 5 - May 6
Total with taxes and fees
This smoke-free hotel features 20 restaurants and 20 bars/lounges. Enjoy a meal in one of the 19 coffee shops/cafes and free perks like cooked-to-order breakfast ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Eastern Panama with star-rating
Check Eastern Panama Hotels by Star Rating
4 Star Hotels
4 properties
Recent Eastern Panama hotel reviews by fellow wanderers
Private Ocean-Front Cabin with private bathroom on San Blas Island
5 out of 5
Posted 2 months ago
Travelocity Verified Review
"Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door. "
A verified traveler stayed at Private Ocean-Front Cabin with private bathroom on San Blas Island
