Book Hotels in Eastern Panama
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top Eastern Panama hotels
Private Ocean-Front Cabin with private bathroom on San Blas Island
Diablo Island Narganá Guna Yala
This hotel features a restaurant, a garden, and a snack bar/deli. Enjoy the free local cuisine breakfast each morning.
Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door.
Reviewed on Mar 15, 2026
Ciel y Miel
Caillle Principale Cacique Provincia de Colón
Fully refundableReserve now, pay when you stay
$207 nightly
The price is $228 total per night from May 19 to May 20
$228 total
May 19 - May 20
Total with taxes and fees
A full-service spa, 3 restaurants, and 4 outdoor pools are all featured at this smoke-free hotel. Relax with a drink at the beach bar and enjoy free perks like ...
The views from this mountain-top boutique hotel are extraordinary.
Reviewed on Feb 1, 2026
Ordovician Beach Resort
Isla Grande Isla Grande Colon
$518 nightly
The price is $569 total per night from May 18 to May 19
$569 total
May 18 - May 19
Total with taxes and fees
This smoke-free resort features a private beach, a full-service spa, and 2 restaurants. Relax with free beach cabanas, sun loungers, and beach umbrellas. Relax ...
The resort was outstanding. It exceeded expectations in every way. The service was the best we had in Panama. The cocktails were fun and the food was delicious and they have a vegan menu. We stayed in a king room and it was very private, pristine and well appointed.
Reviewed on Feb 21, 2026
Konsenda San Blas
Llano Cartí Km 11 El Llano Panamá Province
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $68 total per night from May 24 to May 25
$68 total
May 24 - May 25
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Guests will appreciate freebies like continental breakfast and free self parking. A coffee shop, a ...
Great location for bird watching! The hosts were friendly and helpful. It is best to contact them directly using WhatsApp in addition to booking on Expedia.
Reviewed on Feb 13, 2026
Ranchos de Chalia
Portobelo via Puerto Lindo, Unit 3 Puerto Lindo Colón
$123 nightly
The price is $135 total per night from May 28 to May 29
$135 total
May 28 - May 29
Total with taxes and fees
A restaurant and an outdoor pool are featured at this hotel. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, and free ...
Amazing location, beautiful vistas of mountains, forest and ocean. Very relaxing environment with infinity pool. Well maintained grounds. Wonderful breakfast and dinners. Jose and Anna were amazing hosts. Marijka and Garth
Reviewed on Feb 19, 2026
Cocoloco - Catamaran Lagoon 52F SAN BLAS
El Porvenir Narganá Guna Yala
Fully refundableReserve now, pay when you stay
$1,953 nightly
The price is $2,158 total per night from May 18 to May 19
$2,158 total
May 18 - May 19
Total with taxes and fees
A restaurant and a bar/lounge are featured at this property. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A coffee ...
San Blas Private Oceanfront Cabin
C5W9 4M Nusatupo Narganá Guna Yala
$359 nightly
The price is $385 total per night from May 18 to May 19
$385 total
May 18 - May 19
Total with taxes and fees
A restaurant is available at this cabin. Enjoy the free continental breakfast each morning. Take advantage of the area shuttle.
Hotel Cocotal
La Guaira Isla Grande Provincia de Colón
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $109 total per night from May 18 to May 19
$109 total
May 18 - May 19
Total with taxes and fees
This smoke-free hotel features 20 restaurants and 20 bars/lounges. Enjoy a meal in one of the 19 coffee shops/cafes and free perks like cooked-to-order breakfast ...
HOTEL ISLA GRANDE
Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
$110 nightly
The price is $121 total per night from May 18 to May 19
$121 total
May 18 - May 19
Total with taxes and fees
This hotel features a restaurant, a bar/lounge, and a beach bar. If you want to take your pet along, this pet-friendly property offers everything you'll need ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Eastern Panama with star-rating
Check Eastern Panama Hotels by Star Rating
4 Star Hotels
4 properties
Recent Eastern Panama hotel reviews by fellow wanderers
Private Ocean-Front Cabin with private bathroom on San Blas Island
5 out of 5
Posted 2 months ago
Travelocity Verified Review
"Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door. "
A verified traveler stayed at Private Ocean-Front Cabin with private bathroom on San Blas Island
