Book Hotels in Mayo, SC

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Oct 9 - Oct 11
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Top Mayo hotels

Best Western Spartanburg I-26

Best Western Spartanburg I-26

2 out of 5
488 South Blackstock Road Spartanburg SC
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $108 total per night from Oct 11 to Oct 12
$108 total
Oct 11 - Oct 12
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"Shouldn’t call it a hotel. Motel 8 fits better."

Reviewed on Oct 2, 2026

Opens in a new windowBest Western Spartanburg I-26
Spartanburg Marriott

Spartanburg Marriott

3.5 out of 5
299 North Church Street Spartanburg SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $131 total per night from Oct 11 to Oct 12
$131 total
Oct 11 - Oct 12
Total with taxes and fees
This smoke-free hotel features 3 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free ...
"Professional and polite staff, the grounds were well maintained, ample useful and attractive all while being well located for my purposes."

Reviewed on Sep 28, 2026

Opens in a new windowSpartanburg Marriott
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

2.5 out of 5
161 Sha Ln Spartanburg SC
Fully refundable
$127 nightly
The price is $141 total per night from Oct 25 to Oct 26
$141 total
Oct 25 - Oct 26
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"2 queen beds are sheets were DAMP. At first thought it was because Air conditioning was not on and humidity.. not sure if beds were made and sheets not completely dry and staff thought would dry out by our arrival at 10pm but forgot to turn on air so they stayed sealed under blankets and damp. Was ..."

Reviewed on Oct 1, 2026

Opens in a new windowHoliday Inn Express Hotel & Suites Spartanburg-North by IHG
Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall

2.5 out of 5
458 West Blackstock Road Spartanburg SC
Fully refundable
$90 nightly
The price is $100 total per night from Nov 1 to Nov 2
$100 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Opens in a new windowComfort Suites At WestGate Mall
Four Points by Sheraton Spartanburg

Four Points by Sheraton Spartanburg

3 out of 5
9027 Fairforest Rd Spartanburg SC
Fully refundableReserve now, pay when you stay
$112 nightly
The price is $124 total per night from Oct 11 to Oct 12
$124 total
Oct 11 - Oct 12
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowFour Points by Sheraton Spartanburg
Tru by Hilton Spartanburg

Tru by Hilton Spartanburg

2.5 out of 5
103 Franklin Avenue Spartanburg SC
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $117 total per night from Nov 1 to Nov 2
$117 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Opens in a new windowTru by Hilton Spartanburg
Motel 6 Spartanburg, Sc – Northwest / Business 85

Motel 6 Spartanburg, Sc – Northwest / Business 85

2 out of 5
820 Hospitality Drive Spartanburg SC
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $64 total per night from Oct 18 to Oct 19
$64 total
Oct 18 - Oct 19
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. The front desk is staffed around-the-clock and laundry facilities are ...
Opens in a new windowMotel 6 Spartanburg, Sc – Northwest / Business 85
AC Hotel by Marriott Spartanburg

AC Hotel by Marriott Spartanburg

3.5 out of 5
225 West Main Street Spartanburg SC
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $188 total per night from Oct 11 to Oct 12
$188 total
Oct 11 - Oct 12
Total with taxes and fees
This smoke-free hotel features 3 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in ...
Opens in a new windowAC Hotel by Marriott Spartanburg
Best Western Spartanburg Northwest

Best Western Spartanburg Northwest

3 out of 5
110 Mobile Dr Spartanburg SC
$95 nightly
The price is $105 total per night from Nov 1 to Nov 2
$105 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Opens in a new windowBest Western Spartanburg Northwest
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Mayo?
Great private home in convenient location is a great option for families on their way to Mayo. With useful amenities like a fireplace, this kid-friendly retreat makes guests of all ages feel at home.
Where can I find cheap hotels in Mayo?
At Travelocity you'll find really nice hotels in Mayo at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Mayo rather than in Mayo. We may find you even better rates, too.
How do I find the best Mayo hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Mayo then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Mayo?
The cheapest hotel in Mayo is $64. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Mayo?
There are 499 hotels in Mayo on Travelocity.
What are the best hotels in Mayo?
Mayo has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Mayo for you!
When is the best time to visit Mayo?
If you want the joy of a fun-filled trip in peak season, visit Mayo during March, April and October. If you'd prefer the peace of off-season, book a stay during quieter months, such as December, January and February.
When is the cheapest time to stay in Mayo?
Based on historic data is usually the cheapest month to visit Mayo. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Mayo?
There are multiple hotels in Mayo that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Mayo. We have plenty of kid-friendly hotels in Mayo to choose from on Travelocity!
Why book a hotel in Mayo through Travelocity?
Because we have the top hotels in Mayo! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Mayo on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Mayo hotel reviews by fellow wanderers

Best Western Spartanburg I-26

Best Western Spartanburg I-26

5 out of 5
Posted 19 hours ago
Travelocity Verified Review
"Our stay for one night was exceptional. The service and the room."
A verified traveler stayed at Best Western Spartanburg I-26
Best Western Spartanburg I-26