Book Hotels in La Mesa

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Top La Mesa hotels

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5 out of 5
Santa Maria Boulevard Panama City
Fully refundableReserve now, pay when you stay
$217 nightly
The price is $238 total per night from Feb 15 to Feb 16
$238 total
Feb 15 - Feb 16
Total with taxes and fees
This luxury hotel features a golf course, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
This hôtel is PERFECT ! All the staff is super nice and rooms are 100%. The breakfast is crasy !!

Reviewed on Jan 18, 2026

Opens in a new windowThe Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4 out of 5
Via Israel y Calle 71, San Francisco Panama City Panama
$111 nightly
The price is $122 total per night from Feb 13 to Feb 14
$122 total
Feb 13 - Feb 14
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Great breakfast, super staff and an excellent room. The only problem was the parking. When I signed up for the hotel on Expedia it stated it had parking. It did until I went out and when i returned the parking was full. If you have parking for guest you need to assign a parking place for them and ...

Reviewed on Jan 22, 2026

Opens in a new windowRamada Plaza by Wyndham Panama Punta Pacifica
Arcadia Condo Suites

Arcadia Condo Suites

2.5 out of 5
Calle rio mar Panama City Panamá Province
Fully refundableReserve now, pay when you stay
$164 nightly
The price is $180 total per night from Jan 25 to Jan 26
$180 total
Jan 25 - Jan 26
Total with taxes and fees
This aparthotel features an outdoor pool and a rooftop terrace. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee shop ...
Modern, well equpped property.

Reviewed on Jan 20, 2026

Opens in a new windowArcadia Condo Suites
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

4 out of 5
Avenida Domingo Diaz via Tocumen San Miguelito Panama
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $111 total per night from Feb 6 to Feb 7
$111 total
Feb 6 - Feb 7
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Great staff and comfortable bed! Quiet.

Reviewed on Jan 18, 2026

Opens in a new windowCourtyard by Marriott Panama Metromall
The Westin Panama

The Westin Panama

4 out of 5
La Rotonda Street, Costa del Este Panama City Panama
$214 nightly
The price is $236 total per night from Feb 21 to Feb 22
$236 total
Feb 21 - Feb 22
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this hotel. Enjoy the 24-hour gym and perks like free WiFi. You'll appreciate the sauna, ...
Staff was ver courteous!!!

Reviewed on Jan 15, 2026

Opens in a new windowThe Westin Panama
Aloft Panama

Aloft Panama

3.5 out of 5
Via Israel & Calle 76 Panama City Panama
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $131 total per night from Feb 1 to Feb 2
$131 total
Feb 1 - Feb 2
Total with taxes and fees
A nightclub, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free ...
The staff were helpful and courteous. The breakfast was awesome.

Reviewed on Jan 10, 2026

Opens in a new windowAloft Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
$114 nightly
The price is $125 total per night from Jan 29 to Jan 30
$125 total
Jan 29 - Jan 30
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool, onsite laundry facilities, and babysitting. ...
Property is nice but rooms are nothing special.

Reviewed on Jan 20, 2026

Opens in a new windowCrowne Plaza Panama Airport by IHG
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $148 total per night from Feb 13 to Feb 14
$148 total
Feb 13 - Feb 14
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor tennis courts are all featured at this smoke-free resort. Families will appreciate the playground, kid-friendly ...
Great staff

Reviewed on Jan 15, 2026

Opens in a new windowSheraton Grand Panama
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Vía Tocumen Tocumen Panama
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $138 total per night from Jan 26 to Jan 27
$138 total
Jan 26 - Jan 27
Total with taxes and fees
This smoke-free resort features a casino, 2 indoor tennis courts, and a restaurant. Bring the family and enjoy the children's pool, playground, and kid-friendly ...
The room was a good size, and around the pool was nice.

Reviewed on Jan 19, 2026

Opens in a new windowRiande Aeropuerto Hotel & Casino
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in La Mesa?
Take some of the worries out of traveling with little ones by opting for a family-friendly hotel in La Mesa. From well-thought-out amenities to innovative services, these stays offer perks that'll help make your trip run smoothly: You're well catered for at The Jungle Lodge at Kalu Yala - Glamping. It comes with a swimming pool, childcare services and a flair for making families feel welcome. The Camp at Kalu Yala is another great choice. After an exciting day of exploring La Mesa, return to your cozy room and amenities like a swimming pool and a children's club.
Where can I find cheap hotels in La Mesa?
At Travelocity you'll find really nice hotels in La Mesa at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near La Mesa rather than in La Mesa. We may find you even better rates, too.
How do I find the best La Mesa hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in La Mesa then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in La Mesa?
The cheapest hotel in La Mesa is $111. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in La Mesa?
There are 466 hotels in La Mesa on Travelocity.
What are the best hotels in La Mesa?
La Mesa has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in La Mesa for you!
When is the best time to visit La Mesa?
If you want the joy of a fun-filled trip in peak season, visit La Mesa during February, March and May. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, July and December.
When is the cheapest time to stay in La Mesa?
Based on historic data is usually the cheapest month to visit La Mesa. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in La Mesa?
There are multiple hotels in La Mesa that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to La Mesa. We have plenty of kid-friendly hotels in La Mesa to choose from on Travelocity!
Why book a hotel in La Mesa through Travelocity?
Because we have the top hotels in La Mesa! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in La Mesa on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

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