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Oct 9 - Oct 11
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Top La Mesa hotels

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4 out of 5
Via Israel y Calle 71, San Francisco Panama City Panama
$105 nightly
The price is $115 total per night from Nov 1 to Nov 2
$115 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"Location is central to landmarks and sightseeing. Quick and easy transport, bars and restaurants."

Reviewed on Oct 6, 2026

Opens in a new windowRamada Plaza by Wyndham Panama Punta Pacifica
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5 out of 5
Santa Maria Boulevard Panama City
Fully refundableReserve now, pay when you stay
$277 nightly
The price is $304 total per night from Nov 1 to Nov 2
$304 total
Nov 1 - Nov 2
Total with taxes and fees
This luxury hotel features a golf course, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Beautful property, excellent service!"

Reviewed on Oct 5, 2026

Opens in a new windowThe Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments

4 out of 5
Calle rio mar Panama City Panamá Province
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $112 total per night from Oct 29 to Oct 30
$112 total
Oct 29 - Oct 30
Total with taxes and fees
This aparthotel features an outdoor pool and a rooftop terrace. WiFi in public areas is free. Self parking and a coffee shop are also offered on site.
"The complex was magnificent is better than anything I could possibly imagine and the views was breathtaking me and my wife enjoyed every second of our stay"

Reviewed on Oct 5, 2026

Opens in a new windowCorporate Stays Arcadia | Executive Furnished Apartments
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

4 out of 5
Avenida Domingo Diaz via Tocumen San Miguelito Panama
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $111 total per night from Oct 23 to Oct 24
$111 total
Oct 23 - Oct 24
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"Everyone was friendly"

Reviewed on Oct 5, 2026

Opens in a new windowCourtyard by Marriott Panama Metromall
Aloft by Marriott Panama

Aloft by Marriott Panama

3.5 out of 5
Via Israel & Calle 76 Panama City Panama
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $146 total per night from Oct 16 to Oct 17
$146 total
Oct 16 - Oct 17
Total with taxes and fees
A nightclub, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free ...
"Clean room"

Reviewed on Oct 5, 2026

Opens in a new windowAloft by Marriott Panama
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
$185 nightly
The price is $203 total per night from Oct 12 to Oct 13
$203 total
Oct 12 - Oct 13
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor tennis courts are all featured at this smoke-free resort. Families will appreciate the playground, kid-friendly ...
"Clean rooms, comfy bed, helpful staff! Breakfast buffet was very complete with different options"

Reviewed on Oct 6, 2026

Opens in a new windowSheraton Grand Panama
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Vía Tocumen Tocumen Panama
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $119 total per night from Oct 11 to Oct 12
$119 total
Oct 11 - Oct 12
Total with taxes and fees
This smoke-free resort features a casino, 2 indoor tennis courts, and a restaurant. Bring the family and enjoy the children's pool, playground, and kid-friendly ...
"A good place to stay. Close to the airport"

Reviewed on Oct 5, 2026

Opens in a new windowRiande Aeropuerto Hotel & Casino
Express Inn Panama International Airport Hostel

Express Inn Panama International Airport Hostel

1.5 out of 5
Calle Enrique Malek Tocumen
$50 nightly
The price is $54 total per night from Oct 7 to Oct 8
$54 total
Oct 7 - Oct 8
Total with taxes and fees
This hostel features a restaurant, an outdoor pool, and a bar/lounge. Guests will appreciate free perks like free self parking and WiFi in public areas. A terrace, ...
"The hotel is very close to the airport and was very easy to get to. There is also a supermarket within walking distance, which is very convenient if you need groceries, snacks, or drinks during your stay. One thing to be aware of is that the hotel airport shuttle only operates at three specific times. ..."

Reviewed on Sep 29, 2026

Opens in a new windowExpress Inn Panama International Airport Hostel
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
$140 nightly
The price is $154 total per night from Nov 6 to Nov 7
$154 total
Nov 6 - Nov 7
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool, onsite laundry facilities, and babysitting. ...
Opens in a new windowCrowne Plaza Panama Airport by IHG
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in La Mesa?
Take some of the worries out of traveling with little ones by opting for a family-friendly hotel in La Mesa. From well-thought-out amenities to innovative services, these stays offer perks that'll help make your trip run smoothly: You're well catered for at The Jungle Lodge at Kalu Yala - Glamping. It comes with a swimming pool, childcare services and a flair for making families feel welcome. The Camp at Kalu Yala is another great choice. After an exciting day of exploring La Mesa, return to your cozy room and amenities like a swimming pool and a children's club.
Where can I find cheap hotels in La Mesa?
At Travelocity you'll find really nice hotels in La Mesa at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near La Mesa rather than in La Mesa. We may find you even better rates, too.
How do I find the best La Mesa hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in La Mesa then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in La Mesa?
The cheapest hotel in La Mesa is $54. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in La Mesa?
There are 579 hotels in La Mesa on Travelocity.
What are the best hotels in La Mesa?
La Mesa has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in La Mesa for you!
When is the best time to visit La Mesa?
If you want the joy of a fun-filled trip in peak season, visit La Mesa during February, March and May. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, July and December.
When is the cheapest time to stay in La Mesa?
Based on historic data is usually the cheapest month to visit La Mesa. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in La Mesa?
There are multiple hotels in La Mesa that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to La Mesa. We have plenty of kid-friendly hotels in La Mesa to choose from on Travelocity!
Why book a hotel in La Mesa through Travelocity?
Because we have the top hotels in La Mesa! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in La Mesa on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent La Mesa hotel reviews by fellow wanderers

Sheraton Grand Panama

Sheraton Grand Panama

5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Clean rooms, comfy bed, helpful staff! Breakfast buffet was very complete with different options"
A verified traveler stayed at Sheraton Grand Panama
Sheraton Grand Panama