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Top La Mesa hotels

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4 out of 5
Via Israel y Calle 71, San Francisco Panama City Panama
The price is $127 total per night from Jul 3 to Jul 4
$127 total
per night
Jul 3 - Jul 4
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"Great location for getting around the city and also accesible to the airport. Very nice included breakfast and friendly staff, and well equipped and comfortable bedroom. A very good overall experience!"

Reviewed on Jun 28, 2026

Opens in a new windowRamada Plaza by Wyndham Panama Punta Pacifica
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5 out of 5
Santa Maria Boulevard Panama City
Fully refundableReserve now, pay when you stay
The price is $286 total per night from Jul 9 to Jul 10
$286 total
per night
Jul 9 - Jul 10
This luxury hotel features a golf course, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"The hotel was very clean and well kept. They offer a decent breakfast buffet on site which was super beneficial traveling with two toddlers. This hotel caters to golfers but we were able to find things to do in the surrounding areas. There are restaurants on sight and also restaurants right outside ..."

Reviewed on Jun 26, 2026

Opens in a new windowThe Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Arcadia Condo Suites

Arcadia Condo Suites

4 out of 5
Calle rio mar Panama City Panamá Province
Fully refundableReserve now, pay when you stay
The price is $151 total per night from Jun 30 to Jul 1
$151 total
per night
Jun 30 - Jul 1
This aparthotel features an outdoor pool and a rooftop terrace. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee shop ...
"This property was excellent. Check in was easy and they sent out a detailed email with all the info we needed to get in and lock up. The space itself was incredibly clean and beautiful. The pool was beautiful but unfortunately too chilly to fully enjoy at the moment. The view was incredible though. ..."

Reviewed on Jun 26, 2026

Opens in a new windowArcadia Condo Suites
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

4 out of 5
Avenida Domingo Diaz via Tocumen San Miguelito Panama
Fully refundableReserve now, pay when you stay
The price is $111 total per night from Jul 4 to Jul 5
$111 total
per night
Jul 4 - Jul 5
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"Room was clean and staff were courteous and helpful, the property is located next to a modern shopping mall with restaurants and a wide variety of shops and other amenities"

Reviewed on Jun 29, 2026

Opens in a new windowCourtyard by Marriott Panama Metromall
Aloft by Marriott Panama

Aloft by Marriott Panama

3.5 out of 5
Via Israel & Calle 76 Panama City Panama
Fully refundableReserve now, pay when you stay
The price is $135 total per night from Jul 24 to Jul 25
$135 total
per night
Jul 24 - Jul 25
A nightclub, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free ...
"Todo súper bien"

Reviewed on Jun 27, 2026

Opens in a new windowAloft by Marriott Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
The price is $146 total per night from Jul 9 to Jul 10
$146 total
per night
Jul 9 - Jul 10
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool, onsite laundry facilities, and babysitting. ...
"All ok"

Reviewed on Jun 29, 2026

Opens in a new windowCrowne Plaza Panama Airport by IHG
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
The price is $153 total per night from Jul 20 to Jul 21
$153 total
per night
Jul 20 - Jul 21
A full-service spa, 3 restaurants, and 3 outdoor tennis courts are all featured at this smoke-free resort. Families will appreciate the playground, kid-friendly ...
"Bathroom needs some updates, especially the faucets."

Reviewed on Jun 19, 2026

Opens in a new windowSheraton Grand Panama
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Vía Tocumen Tocumen Panama
Fully refundableReserve now, pay when you stay
The price is $130 total per night from Jul 1 to Jul 2
$130 total
per night
Jul 1 - Jul 2
This smoke-free resort features a casino, 2 indoor tennis courts, and a restaurant. Bring the family and enjoy the children's pool, playground, and kid-friendly ...
"I would’ve given this a perfect rating but the shuttle had me waiting for over an hour at the airport and frustrated me to the point of grabbing an Uber."

Reviewed on Jun 27, 2026

Opens in a new windowRiande Aeropuerto Hotel & Casino
Express Inn Panama International Airport Hostel

Express Inn Panama International Airport Hostel

1.5 out of 5
Calle Enrique Malek Tocumen
The price is $54 total per night from Jun 30 to Jul 1
$54 total
per night
Jun 30 - Jul 1
This hostel features a restaurant, an outdoor pool, and a bar/lounge. Guests will appreciate free perks like free self parking and WiFi in public areas. A terrace, ...
"Rosear eliminador de hormigas"

Reviewed on Jun 21, 2026

Opens in a new windowExpress Inn Panama International Airport Hostel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in La Mesa?
Take some of the worries out of traveling with little ones by opting for a family-friendly hotel in La Mesa. From well-thought-out amenities to innovative services, these stays offer perks that'll help make your trip run smoothly: You're well catered for at The Jungle Lodge at Kalu Yala - Glamping. It comes with a swimming pool, childcare services and a flair for making families feel welcome. The Camp at Kalu Yala is another great choice. After an exciting day of exploring La Mesa, return to your cozy room and amenities like a swimming pool and a children's club.
Where can I find cheap hotels in La Mesa?
At Travelocity you'll find really nice hotels in La Mesa at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near La Mesa rather than in La Mesa. We may find you even better rates, too.
How do I find the best La Mesa hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in La Mesa then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in La Mesa?
The cheapest hotel in La Mesa is $54. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in La Mesa?
There are 540 hotels in La Mesa on Travelocity.
What are the best hotels in La Mesa?
La Mesa has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in La Mesa for you!
When is the best time to visit La Mesa?
If you want the joy of a fun-filled trip in peak season, visit La Mesa during February, March and May. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, July and December.
When is the cheapest time to stay in La Mesa?
Based on historic data is usually the cheapest month to visit La Mesa. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in La Mesa?
There are multiple hotels in La Mesa that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to La Mesa. We have plenty of kid-friendly hotels in La Mesa to choose from on Travelocity!
Why book a hotel in La Mesa through Travelocity?
Because we have the top hotels in La Mesa! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in La Mesa on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent La Mesa hotel reviews by fellow wanderers

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

4 out of 5
Posted 9 hours ago
Travelocity Verified Review
"Room was clean and staff were courteous and helpful, the property is located next to a modern shopping mall with restaurants and a wide variety of shops and other amenities"
A verified traveler stayed at Courtyard by Marriott Panama Metromall
Courtyard by Marriott Panama Metromall

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