Book Hotels in Cherokee, AL

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Cherokee hotels

The Stricklin Hotel

The Stricklin Hotel

3.5 out of 5
317 N Court St Florence AL
Fully refundableReserve now, pay when you stay
$185 nightly
The price is $205 total per night from Dec 2 to Dec 3
$205 total
Dec 2 - Dec 3
Total with taxes and fees
This hotel features 2 restaurants and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free ...
"Very nice room. Everything is close walking range"

Reviewed on Nov 2, 2026

Opens in a new windowThe Stricklin Hotel
Spark by Hilton Tuscumbia Muscle Shoals

Spark by Hilton Tuscumbia Muscle Shoals

3.5 out of 5
712 Hwy 72 W Tuscumbia AL
Fully refundableReserve now, pay when you stay
$83 nightly
The price is $92 total per night from Nov 12 to Nov 13
$92 total
Nov 12 - Nov 13
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"Breakfast was not up to par, they could at least had a waffle appliance, hard boiled eggs didn’t do it for me"

Reviewed on Nov 2, 2026

Opens in a new windowSpark by Hilton Tuscumbia Muscle Shoals
Comfort Suites Florence Shoals Area

Comfort Suites Florence Shoals Area

2.5 out of 5
140 Matthew Paul Ct Florence AL
Fully refundable
$86 nightly
The price is $99 total per night from Nov 15 to Nov 16
$99 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Clean room , friendly staff"

Reviewed on Nov 2, 2026

Opens in a new windowComfort Suites Florence Shoals Area
Rustic Cabin overlooking Pickwick Lake

Rustic Cabin overlooking Pickwick Lake

Cherokee AL
This vacation home featured laundry facilities and barbecue grills.
"This was a very quiet and peaceful little cabin up on a hill. Would love to come back again."

Reviewed on Sep 22, 2026

Get rates
Opens in a new windowRustic Cabin overlooking Pickwick Lake
Clarion Inn Sheffield Muscle Shoals

Clarion Inn Sheffield Muscle Shoals

2.5 out of 5
4900 Hatch Blvd Sheffield AL
Fully refundable
$77 nightly
The price is $86 total per night from Dec 1 to Dec 2
$86 total
Dec 1 - Dec 2
Total with taxes and fees
A nightclub and a restaurant are featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Honestly this hotel need to be renovated or torn down."

Reviewed on Oct 27, 2026

Opens in a new windowClarion Inn Sheffield Muscle Shoals
RIVERTON LAKESIDE COTTAGE ON PICKWICK LAKE

RIVERTON LAKESIDE COTTAGE ON PICKWICK LAKE

Cherokee AL
This vacation home featured laundry facilities and barbecue grills.
Get rates
Opens in a new windowRIVERTON LAKESIDE COTTAGE ON PICKWICK LAKE
Waterfront cabin-Couples getaway *Private hot tub*

Waterfront cabin-Couples getaway *Private hot tub*

Cherokee AL
A hot tub is featured at this apartment, along with barbecue grills.
Get rates
Opens in a new windowWaterfront cabin-Couples getaway *Private hot tub*
Days Inn by Wyndham Muscle Shoals Florence

Days Inn by Wyndham Muscle Shoals Florence

2 out of 5
2701 Woodward Ave Muscle Shoals AL
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $79 total per night from Nov 3 to Nov 4
$79 total
Nov 3 - Nov 4
Total with taxes and fees
A gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like full breakfast and WiFi in public areas. ...
Opens in a new windowDays Inn by Wyndham Muscle Shoals Florence
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

2.5 out of 5
180 Etta Gray Street Florence AL
Fully refundable
$105 nightly
The price is $121 total per night from Nov 8 to Nov 9
$121 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Opens in a new windowHoliday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
Don't see what you're looking for?
See all available properties in Cherokee
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Cherokee?
Take some of the struggles out of traveling with young ones by opting for a family-friendly Cherokee hotel. From thoughtful amenities to extra-helpful services, these properties offer perks that'll make your visit run smoothly: Driftwood Retreat on Tennessee River/Pickwick Lake will help make your vacation the best one yet. It features an assortment of conveniences aimed at families, such as a playground and cycling. Otherwise, spend your Cherokee break at Peaceful Alabama Cabin on Secluded Acreage!. Take advantage of a barbecue grill, a patio and more here.
Where can I find cheap hotels in Cherokee?
At Travelocity you'll find really nice hotels in Cherokee at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Cherokee rather than in Cherokee. We may find you even better rates, too.
How do I find the best Cherokee hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Cherokee then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Cherokee?
The cheapest hotel in Cherokee is $79. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Cherokee?
There are 377 hotels in Cherokee on Travelocity.
What are the best hotels in Cherokee?
Cherokee has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Cherokee for you!
When is the best time to visit Cherokee?
If you want the joy of a fun-filled trip in peak season, visit Cherokee during April, May and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, August and December.
When is the cheapest time to stay in Cherokee?
Based on historic data is usually the cheapest month to visit Cherokee. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Cherokee?
There are multiple hotels in Cherokee that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Cherokee. We have plenty of kid-friendly hotels in Cherokee to choose from on Travelocity!
Why book a hotel in Cherokee through Travelocity?
Because we have the top hotels in Cherokee! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Cherokee on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Cherokee hotel reviews by fellow wanderers

Comfort Suites Florence Shoals Area

Comfort Suites Florence Shoals Area

5 out of 5
Posted 8 hours ago
Travelocity Verified Review
"Clean room , friendly staff"
A verified traveler stayed at Comfort Suites Florence Shoals Area
Comfort Suites Florence Shoals Area

Explore More Ways to Travel with Travelocity