Book Hotels in Cherokee, AL
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Top Cherokee hotels

Driftwood Retreat on Tennessee River/Pickwick Lake
Cherokee AL
This vacation home features a garden, laundry facilities, and barbecue grills.
This property was extremely beautiful and had so much personality. Loved the stay. We would come back for sure. Highly recommend.
Reviewed on Dec 15, 2025

Private Hot Tub, Fire Pit! Pickwick Lake Escape
Cherokee Alabama
A hot tub is featured at this cabin, along with barbecue grills.
All great
Reviewed on Feb 15, 2026

Renaissance Shoals Resort & Spa
10 Hightower Place Florence AL
Fully refundableReserve now, pay when you stay
$269 nightly
The price is $309 total per night from Mar 8 to Mar 9
$309 total
Mar 8 - Mar 9
Total with taxes and fees
A full-service spa, 2 restaurants, and 2 hot tubs are all featured at this smoke-free resort. Traveling on business? Take advantage of the free WiFi in public ...
I stayed overnight for a leadership conference. My room was ready early so that was a plus. I had a balcony overlooking the pool with a river view, in which I witnessed an amazing sunrise. I did have an issue with the cleanliness of my shower. There was long dark hair on the shower wall where someone ...
Reviewed on Mar 3, 2026

The Stricklin Hotel
317 N Court St Florence AL
Fully refundableReserve now, pay when you stay
$177 nightly
The price is $196 total per night from Mar 8 to Mar 9
$196 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features 2 restaurants and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free ...
Yes,
Reviewed on Mar 5, 2026

The ColdWater Inn
712 Hwy 72 W Tuscumbia AL
$93 nightly
The price is $103 total per night from Mar 8 to Mar 9
$103 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
I was very surprised to walk in and the place was being renovated. They were still working at 6:30pm. We were on the third floor so it was peaceful in our room. I was very upset that there was no machines in the hotel. I am ok with the renovations but they could have left at least one ice machine ...
Reviewed on Mar 3, 2026

Comfort Suites Florence Shoals Area
140 Matthew Paul Ct Florence AL
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $131 total per night from Mar 22 to Mar 23
$131 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Very clean
Reviewed on Feb 19, 2026

Rustic Cabin overlooking Pickwick Lake
Cherokee AL
This vacation home featured laundry facilities and barbecue grills.
So hot when we got there we were soaked kitchen was a furnace tried to make sandwiches cheese melted on counter tv did not work til day we left leather couch is terrible springs broke water looked like milk sponges came with building balcony had wasps n dirt dobbers power went out 5 times first night ...
Reviewed on Aug 8, 2025

Days Inn by Wyndham Muscle Shoals Florence
2701 Woodward Ave Muscle Shoals AL
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $76 total per night from Apr 5 to Apr 6
$76 total
Apr 5 - Apr 6
Total with taxes and fees
A gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like full breakfast and WiFi in public areas. ...
Clean room. Nice people.
Reviewed on Mar 4, 2026

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
1852 Highway 72 E Tuscumbia AL
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Mar 7 to Mar 8
$70 total
Mar 7 - Mar 8
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
The room had a smell... and the carpet needs to be replaced dirty and stained. Towel's and wash cloths were rough.
Reviewed on Mar 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Cherokee hotel reviews by fellow wanderers

The Stricklin Hotel
3 out of 5
Posted 5 hours ago
Travelocity Verified Review
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A verified traveler stayed at The Stricklin Hotel
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