Explore top 2025 5 Star Hotels in Santorini
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Top Santorini 5 Star hotels
Santo Pure Oia Suites & Villas
Oia, Santorini
$276 nightly
The price is $331 total per night from Oct 28 to Oct 29
$331 total
Oct 28 - Oct 29
Total with taxes and fees
A full-service spa, 6 outdoor pools, and a hot tub are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public areas, ...
9.4/10 Exceptional! (480 reviews)
"Pool was freezing but it is October so it’s expected. Clean room, staff is nice."
Reviewed on Oct 7, 2025
NOŪS Santorini
Mesaria, Santorini, Santorini Island
$307 nightly
The price is $366 total per night from Oct 13 to Oct 14
$366 total
Oct 13 - Oct 14
Total with taxes and fees
A full-service spa, 2 restaurants, and a gym are all featured at this luxury resort. Enjoy the steam room and free perks like full breakfast and free self parking. ...
9.8/10 Exceptional! (111 reviews)
"This was an amazingggg resort in Santorini. Close (walkable) to many shops and restaurants down the road. The property is beautiful and spacious.Amazing pool, the main one and personal room pool! The spa has free to use sauna etc . Staff was welcoming. Breakfast delicious. I will definitely be coming ..."
Reviewed on Sep 3, 2025
Antoperla Luxury Hotel & Spa
Perissa, Santorini
A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Enjoy the outdoor pool and free perks like buffet breakfast and free self ...
9.2/10 Wonderful! (249 reviews)
Worth it!
"Everyone was so kind. The food was delicious. The spa was amazing. Location perfect!"
Reviewed on Sep 23, 2025
Andronis Arcadia Hotel
Oia, Santorini, Santorini Island
$484 nightly
The price is $567 total per night from Oct 19 to Oct 20
$567 total
Oct 19 - Oct 20
Total with taxes and fees
A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Relax with a drink at one of the 2 poolside bars and enjoy free perks like ...
9.6/10 Exceptional! (192 reviews)
"Must stay.. no complaints and excellent service."
Reviewed on Sep 24, 2025
Andronis Luxury Suites
Oia, Santorini, Santorini Island
$582 nightly
The price is $679 total per night from Oct 26 to Oct 27
$679 total
Oct 26 - Oct 27
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy the hot tub and free perks like full breakfast and WiFi ...
9.6/10 Exceptional! (238 reviews)
Amazing Luxurious Santorini Hotel !
"We had an amazing hotel stay at the Andronis Luxury Suites. The room was large, comfortable bed , large bathrooms and large area for a closet . The views are simply SPECTACULAR! We had a private pool and after a long day exploring Oia it was the perfect way to unwind and cool off. The staff was also ..."
Reviewed on Sep 24, 2025
The Majestic Hotel
Fira, Santorini, Santorini Island
$168 nightly
The price is $208 total per night from Oct 14 to Oct 15
$208 total
Oct 14 - Oct 15
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and a gym. There's fun for all ages with a children's pool and a playground, and families will appreciate ...
9/10 Wonderful! (539 reviews)
"Great option, 10 minutes from town with views of sunset and sunrise. The service staff was amazing, Amin and his bar tender at night and Dora and her colleague in the morning had smiles and no request was not tended to very quickly. I really appreciated my stay and believe you will too!"
Reviewed on Oct 5, 2025
Santorini Princess Spa Hotel
Imerovigli, Santorini, Santorini Island
$136 nightly
The price is $171 total per night from Oct 16 to Oct 17
$171 total
Oct 16 - Oct 17
Total with taxes and fees
A full-service spa, a hot tub, and a restaurant are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and free perks like buffet breakfast ...
9.8/10 Exceptional! (1,002 reviews)
"Everything was perfect"
Reviewed on Oct 2, 2025
Canaves Epitome - Small Luxury Hotels of the World
Eparchiaki Odos Oia, Santorini, Santorini Island
Fully refundableReserve now, pay when you stay
$446 nightly
The price is $523 total per night from Oct 25 to Oct 26
$523 total
Oct 25 - Oct 26
Total with taxes and fees
A full-service spa, 2 restaurants, and 2 outdoor pools are all featured at this luxury hotel. Enjoy the gym and free perks like full breakfast and free self ...
9.8/10 Exceptional! (156 reviews)
"Outstanding hotel, outstanding property, outstanding service, and staff"
Reviewed on Oct 5, 2025
Pegasus Spa Hotel
Imerovigli, Santorini, Santorini Island
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public ...
9.2/10 Wonderful! (176 reviews)
"A Truly Exceptional Stay at the Pegasus Hotel From the moment we arrived at the Pegasus Hotel, we knew we were in for something special. The staff went above and beyond to make our experience unforgettable. Euthimhs, John, Maria, Efi, and Lona were all incredibly welcoming and attentive, offering ..."
Reviewed on Aug 17, 2025
De Sol Spa Hotel
Fira, Santorini, Santorini Island
$234 nightly
The price is $283 total per night from Oct 13 to Oct 14
$283 total
Oct 13 - Oct 14
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free ...
9.2/10 Wonderful! (519 reviews)
"No restaurants within walking distance but The hotel offered a free shuttle both ways to the capital town of Fira (2miles away) where there were plenty of eateries. The concierge booked us 2 incredible excursions - the first was a private guided tour by car around the island (5 hours). The second ..."
Reviewed on Oct 10, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Santorini Resorts & 5 Star Hotels
Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Santorini to make sure your trip is as extravagantly comfortable as you expect.
Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!
Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.
For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Santorini 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.
Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Santorini before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.
Recent Santorini hotel reviews by fellow wanderers
De Sol Spa Hotel
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"No restaurants within walking distance but The hotel offered a free shuttle both ways to the capital town of Fira (2miles away) where there were plenty of eateries. The concierge booked us 2 incredible excursions - the first was a private guided tour by car around the island (5 hours). The second was a day/sunset catamaran cruise. "
A verified traveler stayed at De Sol Spa Hotel
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