Explore top 2026 5 Star Hotels in Andean Natural Region

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Top Andean Natural Region 5 Star hotels

NH Collection Medellín Royal

NH Collection Medellín Royal

5 out of 5
Carrera 42 No 5 Sur 130 Medellín Antioquia
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $109 total per night from May 1 to May 2
$109 total
May 1 - May 2
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (1,010 reviews)
Super

Reviewed on Apr 5, 2026

Opens in a new windowNH Collection Medellín Royal
The Click Clack Hotel Medellin

The Click Clack Hotel Medellin

5 out of 5
Calle 10B # 37-29 Medellín Antioquia
Fully refundableReserve now, pay when you stay
$191 nightly
The price is $191 total per night from Apr 12 to Apr 13
$191 total
Apr 12 - Apr 13
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and airport shuttle. ...
9.2/10 Wonderful! (1,133 reviews)
This is one of my favorite spots in the city.

Reviewed on Apr 7, 2026

Opens in a new windowThe Click Clack Hotel Medellin
The Charlee Hotel

The Charlee Hotel

5 out of 5
Calle 9a 37 16 Medellín
Fully refundableReserve now, pay when you stay
$175 nightly
The price is $175 total per night from Apr 29 to Apr 30
$175 total
Apr 29 - Apr 30
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free ...
8.8/10 Excellent! (1,003 reviews)
I had a fantastic stay at this hotel in Medellín. From the moment I arrived, the staff made me feel welcome and were always friendly, helpful, and professional. The check-in process was smooth and they were happy to answer questions and give recommendations for things to do around the city. The room ...

Reviewed on Apr 5, 2026

Opens in a new windowThe Charlee Hotel
Binn Hotel

Binn Hotel

5 out of 5
Carrera 25 No. 10-51 Medellín Antioquia
Fully refundableReserve now, pay when you stay
$187 nightly
The price is $187 total per night from May 7 to May 8
$187 total
May 7 - May 8
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9.2/10 Wonderful! (1,005 reviews)
Love the hotel

Reviewed on Apr 7, 2026

Opens in a new windowBinn Hotel
Medellin Marriott Hotel

Medellin Marriott Hotel

5 out of 5
Calle 1a Sur #43a-83 Medellín
Fully refundableReserve now, pay when you stay
$329 nightly
The price is $329 total per night from Apr 8 to Apr 9
$329 total
Apr 8 - Apr 9
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
8.8/10 Excellent! (601 reviews)
Service was superb, friendly, so eager to please.

Reviewed on Mar 23, 2026

Opens in a new windowMedellin Marriott Hotel
Luxury Suites Prana By Cadissa

Luxury Suites Prana By Cadissa

5 out of 5
Calle 35 # 63B-36 Medellín Antioquia
Fully refundableReserve now, pay when you stay
$126 nightly
The price is $126 total per night from Apr 8 to Apr 9
$126 total
Apr 8 - Apr 9
This apartment's 2 hot tubs and gym are among the featured amenities. Business travelers can take advantage of the free WiFi in public areas. Enjoy the steam ...
9.2/10 Wonderful! (39 reviews)
This is an amazing property. The hosts are exceptional, and the bot is friendly and useful when the host are not available.

Reviewed on Mar 23, 2026

Opens in a new windowLuxury Suites Prana By Cadissa
Ecolodge Palonegro

Ecolodge Palonegro

5 out of 5
KILOMETRO 1 VIA AEROPUERTO PALONEGRO Lebrija Santander
$118 nightly
The price is $118 total per night from Apr 13 to Apr 14
$118 total
Apr 13 - Apr 14
This lodge features free self parking and free WiFi in public areas. Enjoy the 3 hot tubs and free full breakfast each morning. A garden, a lobby fireplace, ...
Opens in a new windowEcolodge Palonegro
HOBBIT HOTEL

HOBBIT HOTEL

5 out of 5
Vereda el Marial El Peñol Antioquia
$105 nightly
The price is $105 total per night from Apr 15 to Apr 16
$105 total
Apr 15 - Apr 16
A rooftop terrace, free self parking, and laundry facilities are featured at this lodge. WiFi in public areas is free. A picnic area and barbecue grills are ...
10/10 Exceptional! (2 reviews)
Had a wonderful stay with Monica and Jairo in their lovely space. The beds were super comfortable, the pillows heavenly, and the towels fluffy. My hosts were very hospitable and made my stay as pleasant as possible. They were eager to help, open feedback, and proactive in terms of resolving issues. ...

Reviewed on Jul 21, 2023

Opens in a new windowHOBBIT HOTEL
30 Living Suites

30 Living Suites

5 out of 5
82C-40 Cl. 30 Medellín Antioquia
This apartment doesn't skimp on freebies - guests receive free full breakfast and free WiFi. Traveling on business? Take advantage of the business center, conference ...
Opens in a new window30 Living Suites
Morph by MOME Stays

Morph by MOME Stays

5 out of 5
Calle 1 #35 - 70 Medellín Antioquia
This apartment features an outdoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Free self parking, a garden, and a ...
Opens in a new windowMorph by MOME Stays
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Andean Natural Region Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Andean Natural Region to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Andean Natural Region 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Andean Natural Region before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Andean Natural Region hotel reviews by fellow wanderers

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