Explore top 2026 4 Star Hotels in Mission Valley

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Top Mission Valley 4 Star hotels

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
$237 nightly
The price is $274 total per night from Apr 5 to Apr 6
$274 total
Apr 5 - Apr 6
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...
9/10 Wonderful! (3,403 reviews)
Hard Rock was very nice, clean and staff was nice. It is catered to mostly adults so I would probably not recommend to stay here with kids next time but a nice hotel nonetheless.

Reviewed on Mar 11, 2026

Opens in a new windowHard Rock Hotel San Diego
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
$245 nightly
The price is $281 total per night from Apr 5 to Apr 6
$281 total
Apr 5 - Apr 6
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 2 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with ...
Opens in a new windowParadise Point Resort & Spa
Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown

4 out of 5
601 Pacific Hwy San Diego CA
Fully refundableReserve now, pay when you stay
$203 nightly
The price is $235 total per night from Apr 2 to Apr 3
$235 total
Apr 2 - Apr 3
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, express check-in, and valet ...
9/10 Wonderful! (1,667 reviews)
We need netflix

Reviewed on Mar 11, 2026

Opens in a new windowEmbassy Suites by Hilton San Diego Bay Downtown
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4 out of 5
1775 E Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
$285 nightly
The price is $328 total per night from Apr 6 to Apr 7
$328 total
Apr 6 - Apr 7
Total with taxes and fees
A full-service spa, 2 restaurants, and 5 outdoor tennis courts are all featured at this Mediterranean resort. There's fun for all ages with a children's pool ...
8.4/10 Very Good! (1,366 reviews)
Clean room, Spa was nice

Reviewed on Mar 11, 2026

Opens in a new windowSan Diego Mission Bay Resort
San Diego Marriott La Jolla

San Diego Marriott La Jolla

4 out of 5
4240 La Jolla Village Dr La Jolla CA
Fully refundableReserve now, pay when you stay
$163 nightly
The price is $188 total per night from Mar 14 to Mar 15
$188 total
Mar 14 - Mar 15
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.6/10 Excellent! (2,277 reviews)
Worst hotel no amenities boring

Reviewed on Mar 9, 2026

Opens in a new windowSan Diego Marriott La Jolla
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

4 out of 5
1441 Quivira Rd San Diego CA
Fully refundableReserve now, pay when you stay
$235 nightly
The price is $270 total per night from Mar 15 to Mar 16
$270 total
Mar 15 - Mar 16
Total with taxes and fees
This smoke-free hotel features a full-service spa, a marina, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...
8.4/10 Very Good! (1,616 reviews)
We were on a four night stay, After the second night we asked for a replenishment of coffee and towels. I expressed my belief that the room should be furnished with coffee daily. The host was cooperative and offered to comp one nights parking which I felt was acceptable. That didn't happen, we were ...

Reviewed on Mar 10, 2026

Opens in a new windowHyatt Regency Mission Bay Spa and Marina
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
$182 nightly
The price is $211 total per night from Mar 19 to Mar 20
$211 total
Mar 19 - Mar 20
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.4/10 Very Good! (6,050 reviews)
Beautiful location and lots to do within blocks!

Reviewed on Mar 11, 2026

Opens in a new windowWyndham San Diego Bayside
San Diego Marriott Gaslamp Quarter

San Diego Marriott Gaslamp Quarter

4 out of 5
660 K St San Diego CA
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $186 total per night from Apr 2 to Apr 3
$186 total
Apr 2 - Apr 3
Total with taxes and fees
A nightclub, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, express ...
8.8/10 Excellent! (1,666 reviews)
Perfect location in Gaslamp. Less than 10 minute walk to the convention center and literally next door to Petco Park. I visited for a conference at the convention center and it was a great walk with a Starbucks on the way. Rooms are a bit dated but they’re clean and spacious. I wish the cleaning ...

Reviewed on Mar 10, 2026

Opens in a new windowSan Diego Marriott Gaslamp Quarter
Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $263 total per night from Mar 19 to Mar 20
$263 total
Mar 19 - Mar 20
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...
9.2/10 Wonderful! (1,515 reviews)
Love this place. Everything was there! A bar for drinking, a pool for lounging, a diner for eating, and a restaurant for more eating. The place was one of a kind, and we plan on coming back.

Reviewed on Mar 9, 2026

Opens in a new windowLafayette Hotel & Club
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

4 out of 5
11915 El Camino Real San Diego CA
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $111 total per night from Apr 9 to Apr 10
$111 total
Apr 9 - Apr 10
Total with taxes and fees
This hotel features an outdoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 9 conference rooms, free WiFi in public areas, ...
8.6/10 Excellent! (2,150 reviews)
Thank you for a clean room!!

Reviewed on Mar 11, 2026

Opens in a new windowDoubleTree by Hilton San Diego - Del Mar
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