Explore top 2026 4 Star Hotels in Mission Valley

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Top Mission Valley 4 Star hotels

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
$237 nightly
The price is $274 total per night from Apr 5 to Apr 6
$274 total
Apr 5 - Apr 6
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...
9/10 Wonderful! (3,406 reviews)
Hard Rock was very nice, clean and staff was nice. It is catered to mostly adults so I would probably not recommend to stay here with kids next time but a nice hotel nonetheless.

Reviewed on Mar 11, 2026

Opens in a new windowHard Rock Hotel San Diego
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
Fully refundableReserve now, pay when you stay
$236 nightly
The price is $274 total per night from Apr 2 to Apr 3
$274 total
Apr 2 - Apr 3
Total with taxes and fees
This hotel features 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (2,897 reviews)
We loved our stay. The staff was helpful and accommodating. The breakfast was top notch.

Reviewed on Mar 11, 2026

Opens in a new windowManchester Grand Hyatt San Diego
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
$245 nightly
The price is $281 total per night from Apr 5 to Apr 6
$281 total
Apr 5 - Apr 6
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 2 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with ...
Opens in a new windowParadise Point Resort & Spa
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

4 out of 5
11915 El Camino Real San Diego CA
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $111 total per night from Apr 9 to Apr 10
$111 total
Apr 9 - Apr 10
Total with taxes and fees
This hotel features an outdoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 9 conference rooms, free WiFi in public areas, ...
8.6/10 Excellent! (2,151 reviews)
Staff is extremely friendly and helpful, beautiful and quiet room, reasonable prices for food and drink including happy hour M-F! Beautiful pool, hot tub and workout room. Location close to ocean and freeways. I would highly recommend.

Reviewed on Mar 12, 2026

Opens in a new windowDoubleTree by Hilton San Diego - Del Mar
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

4 out of 5
1441 Quivira Rd San Diego CA
Fully refundableReserve now, pay when you stay
$227 nightly
The price is $261 total per night from Apr 5 to Apr 6
$261 total
Apr 5 - Apr 6
Total with taxes and fees
This smoke-free hotel features a full-service spa, a marina, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...
8.4/10 Very Good! (1,616 reviews)
We were on a four night stay, After the second night we asked for a replenishment of coffee and towels. I expressed my belief that the room should be furnished with coffee daily. The host was cooperative and offered to comp one nights parking which I felt was acceptable. That didn't happen, we were ...

Reviewed on Mar 10, 2026

Opens in a new windowHyatt Regency Mission Bay Spa and Marina
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
$182 nightly
The price is $211 total per night from Mar 19 to Mar 20
$211 total
Mar 19 - Mar 20
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.4/10 Very Good! (6,051 reviews)
Room was dirty and AC was broken. They gave us a new room after we spoke with them. Then we went to open the door to the new room and heard people talking as I grabbed the door handle, two men walked out. I complained to the manager and he started arguing with me. This place has really gone down ...

Reviewed on Mar 12, 2026

Opens in a new windowWyndham San Diego Bayside
Hilton San Diego/Del Mar

Hilton San Diego/Del Mar

4 out of 5
15575 Jimmy Durante Blvd Del Mar CA
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $176 total per night from Apr 1 to Apr 2
$176 total
Apr 1 - Apr 2
Total with taxes and fees
This resort features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.6/10 Excellent! (1,002 reviews)
Best for horse track goers

Reviewed on Mar 12, 2026

Opens in a new windowHilton San Diego/Del Mar
San Diego Marriott Gaslamp Quarter

San Diego Marriott Gaslamp Quarter

4 out of 5
660 K St San Diego CA
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $186 total per night from Apr 2 to Apr 3
$186 total
Apr 2 - Apr 3
Total with taxes and fees
A nightclub, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, express ...
8.8/10 Excellent! (1,666 reviews)
Perfect location in Gaslamp. Less than 10 minute walk to the convention center and literally next door to Petco Park. I visited for a conference at the convention center and it was a great walk with a Starbucks on the way. Rooms are a bit dated but they’re clean and spacious. I wish the cleaning ...

Reviewed on Mar 10, 2026

Opens in a new windowSan Diego Marriott Gaslamp Quarter
Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $263 total per night from Mar 17 to Mar 18
$263 total
Mar 17 - Mar 18
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...
9.2/10 Wonderful! (1,515 reviews)
Love this place. Everything was there! A bar for drinking, a pool for lounging, a diner for eating, and a restaurant for more eating. The place was one of a kind, and we plan on coming back.

Reviewed on Mar 9, 2026

Opens in a new windowLafayette Hotel & Club
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
$163 nightly
The price is $188 total per night from Apr 1 to Apr 2
$188 total
Apr 1 - Apr 2
Total with taxes and fees
A marina, 5 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi ...
8.4/10 Very Good! (3,370 reviews)
Love how clean it was and spacious

Reviewed on Mar 11, 2026

Opens in a new windowSheraton San Diego Resort
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