Explore top 2026 4 Star Hotels in Clayton
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Top Clayton 4 Star hotels
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $165 total per night from Jul 17 to Jul 18
$165 total
Jul 17 - Jul 18
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
8.6/10 Excellent! (4,216 reviews)
"I enjoyed the breakfast and the people that were there were very friendly."
Reviewed on Jul 11, 2026
Moonrise Hotel
6177 Delmar Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$157 nightly
The price is $186 total per night from Jul 16 to Jul 17
$186 total
Jul 16 - Jul 17
Total with taxes and fees
The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
9/10 Wonderful! (2,011 reviews)
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Reviewed on Jul 10, 2026
The Royal Sonesta Chase Park Plaza St. Louis
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$198 nightly
The price is $234 total per night from Aug 2 to Aug 3
$234 total
Aug 2 - Aug 3
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
9/10 Wonderful! (1,022 reviews)
"We enjoyed our stay!"
Reviewed on Jul 10, 2026
Hilton St. Louis Frontenac
1335 S Lindbergh Blvd Frontenac MO
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $126 total per night from Jul 12 to Jul 13
$126 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.8/10 Excellent! (1,007 reviews)
"Loved this hotel. Beautiful property, with amazing architecture. Room was very clean and nice. Also, it is very close to, and easy to get to, all parts of STL. Definitely recommend staying here!"
Reviewed on Jul 11, 2026
St. Louis Union Station Hotel, Curio Collection by Hilton
1820 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$160 nightly
The price is $190 total per night from Jul 17 to Jul 18
$190 total
Jul 17 - Jul 18
Total with taxes and fees
This luxury hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free WiFi. ...
8.8/10 Excellent! (1,008 reviews)
"Great place but if possible they need to add exits. Too much walking to and from room."
Reviewed on Jul 11, 2026
Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
$122 nightly
The price is $143 total per night from Jul 31 to Aug 1
$143 total
Jul 31 - Aug 1
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
8.4/10 Very Good! (1,119 reviews)
"Beautiful and clean room, very quiet."
Reviewed on Jul 11, 2026
Live by Loews - St.Louis
799 Clark ave St. Louis MO
$159 nightly
The price is $189 total per night from Jul 17 to Jul 18
$189 total
Jul 17 - Jul 18
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
9.4/10 Exceptional! (1,241 reviews)
"Cannot recommend this hotel enough!! Everything about it was amazing! The beds and pillows were the most comfortable I’ve ever had at a hotel. The location was perfect, right next to Busch Stadium and 10-15 mins walking distance from the arch. The staff were all friendly and helpful. The room was ..."
Reviewed on Jul 11, 2026
The Westin St. Louis
811 Spruce St St. Louis MO
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $164 total per night from Jul 19 to Jul 20
$164 total
Jul 19 - Jul 20
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
8.8/10 Excellent! (1,003 reviews)
"Wonderful place to stay if you want close proximity to the Arch and Busch Stadium. I wasn’t a fan of paying $50 to valet my car or pay $24.95 plus tax and tip for breakfast. The staff were very friendly and helpful."
Reviewed on Jul 5, 2026
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from Aug 9 to Aug 10
$173 total
Aug 9 - Aug 10
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (1,960 reviews)
"We Love This Place! Will definitely book here everytime we are in The Lou!"
Reviewed on Jul 10, 2026
River City Casino & Hotel
777 River City Casino Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $115 total per night from Jul 15 to Jul 16
$115 total
Jul 15 - Jul 16
Total with taxes and fees
This hotel features a casino, a nightclub, and 5 restaurants. Traveling on business? Take advantage of the business center, conference center, and conference ...
9.2/10 Wonderful! (1,661 reviews)
"The staff was friendly and courteous. The only real issue was the room next door had an alarm clock that went off from 530 a m to 8 00. The maintenance guy finally got the people next door to shut it off."
Reviewed on Jul 10, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Clayton hotel reviews by fellow wanderers
Forest Park Hotel by MDR
5 out of 5
Posted 3 hours ago
Travelocity Verified Review
"Nice staff"
A verified traveler stayed at Forest Park Hotel by MDR
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