Explore top 2026 4 Star Hotels in Clayton
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Top Clayton 4 Star hotels
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $158 total per night from Jul 19 to Jul 20
$158 total
per night
Jul 19 - Jul 20
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
Moonrise Hotel
6177 Delmar Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $208 total per night from Jul 19 to Jul 20
$208 total
per night
Jul 19 - Jul 20
The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
St. Louis Union Station Hotel, Curio Collection by Hilton
1820 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $201 total per night from Aug 6 to Aug 7
$201 total
per night
Aug 6 - Aug 7
This luxury hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free WiFi. ...
8.8/10 Excellent! (1,017 reviews)
"Only bad thing is wedding took up entire lobby so we did t get to enjoy the nightly light show or lobby bar that is so beautiful on Saturday night…"
Reviewed on Jul 16, 2026
The Royal Sonesta Chase Park Plaza St. Louis
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $234 total per night from Aug 3 to Aug 4
$234 total
per night
Aug 3 - Aug 4
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
Live by Loews - St.Louis
799 Clark ave St. Louis MO
The price is $189 total per night from Jul 17 to Jul 18
$189 total
per night
Jul 17 - Jul 18
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
9.4/10 Exceptional! (1,239 reviews)
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Reviewed on Jul 14, 2026
The Westin St. Louis
811 Spruce St St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $164 total per night from Aug 6 to Aug 7
$164 total
per night
Aug 6 - Aug 7
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
8.6/10 Excellent! (1,010 reviews)
"Hard to get a luggage cart!"
Reviewed on Jul 14, 2026
Hilton St. Louis Frontenac
1335 S Lindbergh Blvd Frontenac MO
Fully refundableReserve now, pay when you stay
The price is $171 total per night from Jul 26 to Jul 27
$171 total
per night
Jul 26 - Jul 27
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.8/10 Excellent! (1,000 reviews)
"Cleanness"
Reviewed on Jul 14, 2026
Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $143 total per night from Jul 31 to Aug 1
$143 total
per night
Jul 31 - Aug 1
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $126 total per night from Aug 3 to Aug 4
$126 total
per night
Aug 3 - Aug 4
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is $173 total per night from Aug 9 to Aug 10
$173 total
per night
Aug 9 - Aug 10
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (1,968 reviews)
"The spa is so amazing, we’d come to St. Louis just for this amenity; loved the galleries too!"
Reviewed on Jul 15, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Clayton hotel reviews by fellow wanderers
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
4 out of 5
Posted 2 hours ago
Travelocity Verified Review
"The property was very clean. I love that the hotel had two pools, one outside and an indoor hot tub. The breakfast was also decent."
A verified traveler stayed at Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
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