Explore the best 2025 4 Star Hotels Hotels in St. Louis
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top St. Louis 4 Star hotels

Hyatt Regency St. Louis at The Arch

Moonrise Hotel

21C Museum Hotel St Louis

St. Louis Union Station Hotel, Curio Collection by Hilton

DoubleTree by Hilton St. Louis Airport

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Renaissance St. Louis Airport Hotel

Ameristar Casino Resort and Spa

Marriott St. Louis Grand

Live by Loews - St.Louis

Hilton St. Louis at the Ballpark

Le Méridien St. Louis Clayton
4 Star Hotels St. Louis
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in St. Louis 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in St. Louis will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in St. Louis, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
St. Louis hotels essential information
Accommodation | 1,773 hotels |
---|---|
Lowest Price | $122 |
Highest Price | $227 |
Popular hotels | Hyatt Regency St. Louis at The Arch, Moonrise Hotel, 21C Museum Hotel St Louis , St. Louis Union Station Hotel, Curio Collection by Hilton, DoubleTree by Hilton St. Louis Airport, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel, Renaissance St. Louis Airport Hotel, Ameristar Casino Resort and Spa, Marriott St. Louis Grand, Live by Loews - St.Louis, Hilton St. Louis at the Ballpark, Le Méridien St. Louis Clayton |
Recent St. Louis hotel reviews by fellow wanderers

Hyatt Regency St. Louis at The Arch
Types of hotels
Hotels near…
Hotels by star rating
Areas of St. Louis
Book on Expedia
More ways to wander St. Louis
Most popular
- Cheap Hotels in Kansas City
- Hotels around Dome at America’s Center
- Hotels around Hollywood Casino Amphitheatre
- 4 Star Hotels in Kansas City
- Kansas City Boutique Hotels
- Kansas City Hotels with Balconies
- Hotels in Downtown St. Louis
- Hotels around Enterprise Center
- Kansas City Casino Resorts & Hotels
- Cheap Hotels in Chesterfield
- Kansas City Hotels with Waterslides
- Kansas City Hotels with Hot Tubs
- Hotels around Busch Stadium
- Kansas City Spa Resorts & Hotels
- Kansas City Kid Friendly Hotels
- Kansas City All Inclusive Resorts & Hotels
- Kansas City Romantic Getaways & Hotels
- 5 Star Hotels in Kansas City
- Kansas City Pet Friendly Hotels
- Cheap Hotels in St. Charles
- Hotels with smoking rooms in Kansas City
- Kansas City Waterpark Hotels and Resorts
- Hotels in St. Charles Historic District
- Kansas City Luxury Hotels