Explore top 2026 4 Star Hotels in Florida Keys
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Top Florida Keys 4 Star hotels
Reefhouse Resort & Marina
103800 Overseas Hwy Key Largo FL
Fully refundableReserve now, pay when you stay
$249 nightly
The price is $275 total per night from Jul 27 to Jul 28
$275 total
Jul 27 - Jul 28
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Family-friendly ...
9.4/10 Exceptional! (1,470 reviews)
"Quiet with everything you need and a great sunset spot."
Reviewed on Jul 2, 2026
Hawks Cay Resort
61 Hawks Cay Blvd Marathon FL
Fully refundableReserve now, pay when you stay
$236 nightly
The price is $264 total per night from Jul 12 to Jul 13
$264 total
Jul 12 - Jul 13
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...
8.2/10 Very Good! (1,002 reviews)
"Wonderful loved it !!"
Reviewed on Jul 3, 2026
Baker's Cay Resort Key Largo, Curio Collection by Hilton
97000 Overseas Hwy Key Largo FL
Fully refundableReserve now, pay when you stay
$319 nightly
The price is $359 total per night from Jul 13 to Jul 14
$359 total
Jul 13 - Jul 14
Total with taxes and fees
A private beach, 2 restaurants, and 2 outdoor pools are all featured at this resort. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
8.6/10 Excellent! (1,124 reviews)
"I will never use Expedia"
Reviewed on Jul 3, 2026
Amara Cay Resort
80001 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$238 nightly
The price is $268 total per night from Jul 8 to Jul 9
$268 total
Jul 8 - Jul 9
Total with taxes and fees
A private beach, 2 restaurants, and an outdoor pool are all featured at this resort. If you want to take your pet along, this pet-friendly property offers everything ...
8.8/10 Excellent! (1,283 reviews)
"We loved everything about it! We will be back!"
Reviewed on Jul 3, 2026
Playa Largo Resort & Spa, Autograph Collection
97450 Overseas Highway Key Largo FL
Fully refundableReserve now, pay when you stay
$328 nightly
The price is $369 total per night from Aug 2 to Aug 3
$369 total
Aug 2 - Aug 3
Total with taxes and fees
This luxury resort features a full-service spa, a marina, and 3 restaurants. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Enjoy the ...
9/10 Wonderful! (1,004 reviews)
"Great I love it"
Reviewed on Jul 2, 2026
Islander Resort
82100 Overseas Highway Islamorada FL
Fully refundableReserve now, pay when you stay
$292 nightly
The price is $329 total per night from Jul 26 to Jul 27
$329 total
Jul 26 - Jul 27
Total with taxes and fees
A private beach, 3 restaurants, and 2 outdoor pools are all featured at this hotel. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Families ...
9.4/10 Exceptional! (1,065 reviews)
"Islander Resort... WOW! This place will WOW you in the keys. From the beautifully decorated rooms that are spacious, to the large patios, to the walkable grounds all in white sand and beautifully clean grounds. You will walk from your rooms towards the BEAUTIFUL view of the Florida bay. Incredible ..."
Reviewed on Jul 2, 2026
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
1996 Overseas Highway Marathon FL
Fully refundableReserve now, pay when you stay
$188 nightly
The price is $212 total per night from Jul 7 to Jul 8
$212 total
Jul 7 - Jul 8
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 4 restaurants. Traveling on business? Take advantage of the 3 conference rooms, along with ...
8.6/10 Excellent! (1,167 reviews)
"Beautiful room. Great area and beautiful grounds"
Reviewed on Jul 2, 2026
La Siesta Resort & Villas
80241 Overseas Highway Islamorada FL
Fully refundableReserve now, pay when you stay
$251 nightly
The price is $283 total per night from Jul 8 to Jul 9
$283 total
Jul 8 - Jul 9
Total with taxes and fees
The private beach and marina are among the highlights at this resort. Enjoy the outdoor pool and perks like a free area shuttle. There's a poolside bar on site, ...
8.6/10 Excellent! (1,003 reviews)
"Clean quiet and serene. Staff was so helpful and kind!"
Reviewed on Jul 3, 2026
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
84001 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$319 nightly
The price is $359 total per night from Jul 14 to Jul 15
$359 total
Jul 14 - Jul 15
Total with taxes and fees
This Art Deco resort features a private beach, a marina, and 4 restaurants. Enjoy a day at the beach snorkeling, or relax with sun loungers. Families will appreciate ...
9/10 Wonderful! (222 reviews)
"Hotel is nice but there is a lot of seaweed!!! so the beach is unusable... We were given a room in Building 7, so far from everything—and had to walk way too much! Some staff are nice and another one rude. There is a lot of thing to do there but sincerely it's not worth the money, no coming ..."
Reviewed on Jun 29, 2026
Tranquility Bay Beachfront Hotel and Resort
2600 Overseas Hwy Marathon FL
Fully refundableReserve now, pay when you stay
$263 nightly
The price is $296 total per night from Jul 6 to Jul 7
$296 total
Jul 6 - Jul 7
Total with taxes and fees
This smoke-free hotel features a private beach, 3 outdoor pools, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy ...
8.8/10 Excellent! (1,003 reviews)
"Beautiful place ❤️"
Reviewed on Jul 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
4 Star Hotels Florida Keys
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Florida Keys 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Florida Keys will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Florida Keys, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Florida Keys hotel reviews by fellow wanderers
Hawks Cay Resort
5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"Wonderful loved it !!"
A verified traveler stayed at Hawks Cay Resort
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