Explore the best 2025 4 Star Hotels Hotels in Florida Keys

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Top Florida Keys 4 Star hotels

Hawks Cay Resort

61 Hawks Cay Blvd, Marathon, FL

$291 nightly

$326 total

Aug 17 - Aug 18

Total includes taxes and fees

This traditional hotel features a private beach, a full-service spa, and a marina. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. There's fun for all ages with a children's pool and a playground, and families will appreciate the picnic area.

On private beach

Pool

Baker's Cay Resort Key Largo, Curio Collection by Hilton

97000 Overseas Hwy, Key Largo, FL

$364 nightly

$409 total

Aug 12 - Aug 13

Total includes taxes and fees

A private beach, 2 restaurants, and 2 outdoor pools are all featured at this resort. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Families will appreciate the arcade/game room and complimentary bicycles.

On private beach

Pool

Islander Resort

82100 Overseas Highway, Islamorada, FL

Free Cancellation

Reserve now, pay when you stay

$268 nightly

$302 total

Aug 11 - Aug 12

Total includes taxes and fees

A private beach, 3 restaurants, and 2 outdoor pools are all featured at this hotel. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Families will appreciate the mini golf and complimentary bicycles.

On private beach

Pool

Amara Cay Resort

80001 Overseas Hwy, Islamorada, FL

Free Cancellation

Reserve now, pay when you stay

$222 nightly

$250 total

Aug 12 - Aug 13

Total includes taxes and fees

A private beach, 2 restaurants, and an outdoor pool are all featured at this resort. If you want to take your pet along, this pet-friendly property offers everything you'll need for your pet including food and water bowls. Enjoy the gym and visit the 3 bars/lounges and poolside bar for drinks.

On private beach

Pool

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

1996 Overseas Highway, Marathon, FL

Free Cancellation

Reserve now, pay when you stay

$179 nightly

$201 total

Aug 10 - Aug 11

Total includes taxes and fees

A marina, 4 restaurants, and 2 outdoor pools are all featured at this smoke-free resort. Traveling on business? Take advantage of the 3 conference rooms, along with free WiFi in public areas. Enjoy the 24-hour gym and visit the 2 bars/lounges and poolside bar for drinks.

Pool

Pet friendly

Playa Largo Resort & Spa, Autograph Collection

97450 Overseas Highway, Key Largo, FL

Free Cancellation

Reserve now, pay when you stay

$312 nightly

$351 total

Aug 17 - Aug 18

Total includes taxes and fees

This luxury resort features a full-service spa, a marina, and 3 restaurants. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Enjoy the outdoor pool and perks like free WiFi.

Pool

Hot Tub

La Siesta Resort & Villas

80241 Overseas Highway, Islamorada, FL

Free Cancellation

Reserve now, pay when you stay

$198 nightly

$223 total

Jul 27 - Jul 28

Total includes taxes and fees

The private beach and marina are among the highlights at this resort. Enjoy the outdoor pool and perks like a free area shuttle. There's a poolside bar on site, and a 24-hour front desk and wedding services are also provided.

On private beach

Pool

Tranquility Bay Beachfront Hotel and Resort

2600 Overseas Hwy, Marathon, FL

Free Cancellation

Reserve now, pay when you stay

$281 nightly

$317 total

Aug 17 - Aug 18

Total includes taxes and fees

This smoke-free hotel features a private beach, 3 outdoor pools, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy the gym and perks like free self parking.

On private beach

Pool

Villas At Hawks Cay Resort

61 Hawks Cay Boulevard, Villas, Marathon, FL

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This luxury resort features a private beach, a full-service spa, and a marina. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Bring the family and enjoy the children's pool, playground, and arcade/game room.

On private beach

Pool

The Islands of Islamorada

82779 Old Hwy, Islamorada, FL

Free Cancellation

Reserve now, pay when you stay

$594 nightly

$668 total

Aug 1 - Aug 2

Total includes taxes and fees

2 outdoor pools, a 24-hour gym, and a hot tub are all featured at this smoke-free villa. Spend a day at the beach kayaking, or relax with sun loungers and beach umbrellas. Families will appreciate the playground and barbecue grills.

Pool

Hot Tub

The Reef at Marathon, Florida Keys

6800 Overseas Hwy, Marathon, FL

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This condo's 2 outdoor tennis courts and outdoor pool are among the featured amenities. Guests will appreciate free perks like free self parking and WiFi in public areas. A picnic area, laundry facilities, and barbecue grills are also on offer.

Pool

Kitchen

The Caribbean Resort Coconut Palm North

117 South Carroll Street, Islamorada, FL

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A marina and an outdoor pool are featured at this smoke-free vacation home. Free self parking and a convenience store are also offered on site.

Pool

Parking included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Florida Keys

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Florida Keys 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Florida Keys will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Florida Keys, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Florida Keys hotels essential information

Accommodation	8,273 hotels
Lowest Price	$201
Highest Price	$668
Popular hotels	Hawks Cay Resort, Baker's Cay Resort Key Largo, Curio Collection by Hilton, Islander Resort, Amara Cay Resort, Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton, Playa Largo Resort & Spa, Autograph Collection, La Siesta Resort & Villas, Tranquility Bay Beachfront Hotel and Resort, Villas At Hawks Cay Resort, The Islands of Islamorada, The Reef at Marathon, Florida Keys, The Caribbean Resort Coconut Palm North

Recent Florida Keys hotel reviews by fellow wanderers

Holiday Inn Key Largo by IHG

5 out of 5

Posted 20 hours ago

Travelocity Verified Review

"Traveled to the keys for the weekend to look at a venue for my son’s wedding. This hotel was quite pleasant and the service was nice and accommodating and there was a restaurant on site as well as off and many local. There pool with the bar was a nice feature as well! "

A verified traveler stayed at Holiday Inn Key Largo by IHG