Explore top 2025 4 Star Hotels in Andrews

Name: Odessa Marriott Hotel & Conference Center
Price range: $206 total
Rating: 9

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Top Andrews 4 Star hotels

Wyndham Midland Downtown

117 West Wall Street, Midland, TX

Fully refundableReserve now, pay when you stay

$74 nightly

$85 total

Oct 17 - Oct 18

Total with taxes and fees

The hotel's outdoor pool, 24-hour gym, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the 24-hour business center, ...

7.6/10 Good! (310 reviews)

"I didn’t use either one"

Reviewed on Oct 9, 2025

Odessa Marriott Hotel & Conference Center

305 East 5th Street, Odessa, TX

Fully refundableReserve now, pay when you stay

$179 nightly

$206 total

Oct 24 - Oct 25

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

9/10 Wonderful! (446 reviews)

"Very good , thanks"

Reviewed on Sep 28, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Andrews

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Andrews 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Andrews will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Andrews, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.