Book Hotels in Syracuse, MO

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Syracuse hotels

Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel

Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel

3 out of 5
103 E 4th St Sedalia MO
Fully refundable
$110 nightly
The price is $125 total per night from Sep 27 to Sep 28
$125 total
Sep 27 - Sep 28
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests ...
"Loved this stay!"

Reviewed on Aug 25, 2026

Opens in a new windowHotel Bothwell Sedalia Central District, an Ascend Collection Hotel
Best Western State Fair Inn

Best Western State Fair Inn

3 out of 5
3120 S Limit Sedalia MO
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $146 total per night from Aug 30 to Aug 31
$146 total
Aug 30 - Aug 31
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of the business ...
"Clean, smaller, comfortable room. Breakfast was good with real cage free organic scrambled eggs, sausage, biscuits and gravy."

Reviewed on Aug 25, 2026

Opens in a new windowBest Western State Fair Inn
Quality Inn & Suites Boonville - Columbia

Quality Inn & Suites Boonville - Columbia

2.5 out of 5
2427 Mid America Industrial Dr Boonville MO
Fully refundable
$97 nightly
The price is $110 total per night from Sep 27 to Sep 28
$110 total
Sep 27 - Sep 28
Total with taxes and fees
An indoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like buffet breakfast and WiFi in public ...
"Beds where nice and clean and comfortable. Towels felt soft and nice. The room was very humid when we checked in because ac was off. But overall it was a great stay."

Reviewed on Aug 16, 2026

Opens in a new windowQuality Inn & Suites Boonville - Columbia
Super 7 Motel Sedalia

Super 7 Motel Sedalia

2.5 out of 5
5650 S Limit Ave Sedalia MO
Fully refundableReserve now, pay when you stay
$56 nightly
The price is $62 total per night from Aug 30 to Aug 31
$62 total
Aug 30 - Aug 31
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, laundry facilities, and barbecue grills are also on offer.
"Our room did Not have toilet tissue, I had to send my husband to the office to get a roll while I sat there. The room had a strong air freshener smell. The beds were not comfortable, old mattress."

Reviewed on Aug 19, 2026

Opens in a new windowSuper 7 Motel Sedalia
Econo Lodge Truman Inn

Econo Lodge Truman Inn

2 out of 5
3501 W Broadway Blvd Sedalia MO
This hotel features an indoor pool and a hot tub. Business travelers can take advantage of the free WiFi in public areas. Enjoy the sauna and free perks like ...
"clean room, very friendly staff."

Reviewed on Aug 28, 2026

Get rates
Opens in a new windowEcono Lodge Truman Inn
Days Inn by Wyndham Boonville

Days Inn by Wyndham Boonville

2 out of 5
2401 Pioneer St Boonville MO
Fully refundableReserve now, pay when you stay
$50 nightly
The price is $57 total per night from Sep 1 to Sep 2
$57 total
Sep 1 - Sep 2
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the free WiFi in public areas and onsite conference space. Free self ...
"Roach bug infested. Air did not work."

Reviewed on Aug 28, 2026

Opens in a new windowDays Inn by Wyndham Boonville
Motel 6 Sedalia, MO

Motel 6 Sedalia, MO

2 out of 5
3402 W Broadway Blvd Sedalia MO
Fully refundableReserve now, pay when you stay
$53 nightly
The price is $61 total per night from Sep 12 to Sep 13
$61 total
Sep 12 - Sep 13
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A snack bar/deli, laundry facilities, and free newspapers are also on ...
"Laundry mostly broken staff not much help hallways stink"

Reviewed on Aug 25, 2026

Opens in a new windowMotel 6 Sedalia, MO
American Inn Sedalia

American Inn Sedalia

2.5 out of 5
1217 S Limit Ave Sedalia MO
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $63 total per night from Aug 30 to Aug 31
$63 total
Aug 30 - Aug 31
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the business center. The front ...
"The property is very rundown and not as expected for the money we paid"

Reviewed on Aug 28, 2026

Opens in a new windowAmerican Inn Sedalia
Comfort Inn Sedalia Station

Comfort Inn Sedalia Station

2.5 out of 5
3600 W Broadway Blvd Sedalia MO
Fully refundable
$115 nightly
The price is $131 total per night from Sep 4 to Sep 5
$131 total
Sep 4 - Sep 5
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...
Opens in a new windowComfort Inn Sedalia Station
Don't see what you're looking for?
See all available properties in Syracuse
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Syracuse?
Take some of the hassles out of traveling with kids by booking a family-friendly Syracuse hotel. From well-thought-out amenities to extra-helpful services, these stays offer perks that'll help make your getaway run like a dream: You'll be well taken care of at Unique Creekside Escape - Enjoy 300+ Goats!. It comes with a barbecue grill, internet access and a commitment to making families feel at home. Also look into Western Hills Motel. It comes with a swimming pool, a picnic area and plenty of opportunities to hang out together.
Where can I find cheap hotels in Syracuse?
At Travelocity you'll find really nice hotels in Syracuse at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Syracuse rather than in Syracuse. We may find you even better rates, too.
How do I find the best Syracuse hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Syracuse then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Syracuse?
The cheapest hotel in Syracuse is $57. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Syracuse?
There are 91 hotels in Syracuse on Travelocity.
What are the best hotels in Syracuse?
Syracuse has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Syracuse for you!
When is the best time to visit Syracuse?
If you want the joy of a fun-filled trip in peak season, visit Syracuse during March, April and July. If you'd prefer the peace of off-season, book a stay during quieter months, such as August, October and December.
When is the cheapest time to stay in Syracuse?
Based on historic data is usually the cheapest month to visit Syracuse. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Syracuse?
There are multiple hotels in Syracuse that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Syracuse. We have plenty of kid-friendly hotels in Syracuse to choose from on Travelocity!
Why book a hotel in Syracuse through Travelocity?
Because we have the top hotels in Syracuse! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Syracuse on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Syracuse hotel reviews by fellow wanderers

Econo Lodge Truman Inn

Econo Lodge Truman Inn

4 out of 5
Posted 13 hours ago
Travelocity Verified Review
"clean room, very friendly staff."
A verified traveler stayed at Econo Lodge Truman Inn
Econo Lodge Truman Inn

Explore More Ways to Travel with Travelocity