Book Hotels in Syracuse, MO

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Syracuse hotels

Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel

Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel

3 out of 5
103 E 4th St Sedalia MO
Fully refundable
$110 nightly
The price is $126 total per night from Apr 20 to Apr 21
$126 total
Apr 20 - Apr 21
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests ...
Loved the nostalgia!!

Reviewed on Mar 17, 2026

Opens in a new windowHotel Bothwell Sedalia Central District, an Ascend Collection Hotel
Comfort Inn Sedalia Station

Comfort Inn Sedalia Station

2.5 out of 5
3600 W Broadway Blvd Sedalia MO
Fully refundable
$109 nightly
The price is $124 total per night from Apr 2 to Apr 3
$124 total
Apr 2 - Apr 3
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...
The breakfast is your typical continental breakfast so nothing to get too excited about. Other than that is near plenty of restaurants and centrally located in Sedalia.

Reviewed on Mar 4, 2026

Opens in a new windowComfort Inn Sedalia Station
Best Western State Fair Inn

Best Western State Fair Inn

3 out of 5
3120 S Limit Sedalia MO
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $140 total per night from Mar 27 to Mar 28
$140 total
Mar 27 - Mar 28
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of the business ...
This was a second stay for me at this Best Western in Sedalia, MO. It is an older facility, but they work hard to keep everything in good condition and working order. The folks are always nice, and it is one of the better breakfasts around.

Reviewed on Mar 17, 2026

Opens in a new windowBest Western State Fair Inn
Quality Inn & Suites Boonville - Columbia

Quality Inn & Suites Boonville - Columbia

2.5 out of 5
2427 Mid America Industrial Dr Boonville MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $105 total per night from Mar 23 to Mar 24
$105 total
Mar 23 - Mar 24
Total with taxes and fees
An indoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like buffet breakfast and WiFi in public ...
No pool even though advertised - under “construction”. Room condition was poor, hallways smelled, and the hotel is directly by a truck stop so there were loud semi truck engines all night. No kids programming available on the tv either. I would have left as soon as we checked in and saw no pool, ...

Reviewed on Mar 18, 2026

Opens in a new windowQuality Inn & Suites Boonville - Columbia
Super 8 by Wyndham Boonville

Super 8 by Wyndham Boonville

2.5 out of 5
420 Americana Boonville MO
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $63 total per night from Mar 26 to Mar 27
$63 total
Mar 26 - Mar 27
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Left just as tired as when I got there. Was on ground floor (rm 102) heard people walking around floor above. 430am woke up by them walking (sounding more like stomping or heavy footsteps) tried to get back to sleep and couldn't. Ended up leaving 6 hours after I stopped. Waste of time and money and ...

Reviewed on Mar 15, 2026

Opens in a new windowSuper 8 by Wyndham Boonville
Super 7 Motel Sedalia

Super 7 Motel Sedalia

2.5 out of 5
5650 S Limit Ave Sedalia MO
Fully refundable
$51 nightly
The price is $57 total per night from Mar 30 to Mar 31
$57 total
Mar 30 - Mar 31
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, laundry facilities, and barbecue grills are also on offer.
There was mold in there and it weighed heavy on my lungs

Reviewed on Feb 17, 2026

Opens in a new windowSuper 7 Motel Sedalia
Days Inn by Wyndham Boonville

Days Inn by Wyndham Boonville

2 out of 5
2401 Pioneer St Boonville MO
Fully refundableReserve now, pay when you stay
$42 nightly
The price is $47 total per night from Mar 23 to Mar 24
$47 total
Mar 23 - Mar 24
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the free WiFi in public areas and onsite conference space. Free self ...
Coffee place next door. Two gas stations within walking distance. Had a last minute reservation, but both the two lamps above the bed had broken wires and just wrapped around the fixture. Also had two tvs on the entertainment center which was different but not much of a problem. Room needs some work ...

Reviewed on Mar 18, 2026

Opens in a new windowDays Inn by Wyndham Boonville
Econo Lodge Truman Inn

Econo Lodge Truman Inn

2 out of 5
3501 W Broadway Blvd Sedalia MO
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $92 total per night from Mar 22 to Mar 23
$92 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Business travelers can take advantage of the free WiFi in public areas. Enjoy the sauna and free perks like ...
The room floor was dirty, the room and the entire hotel smelled bad, during the stay, no cleaning was provided, no one did our beds, nor pulled the trash. No paper towel restock.

Reviewed on Mar 17, 2026

Opens in a new windowEcono Lodge Truman Inn
Motel 6 Sedalia, MO

Motel 6 Sedalia, MO

2 out of 5
3402 W Broadway Blvd Sedalia MO
Fully refundableReserve now, pay when you stay
$49 nightly
The price is $56 total per night from Apr 14 to Apr 15
$56 total
Apr 14 - Apr 15
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A snack bar/deli, laundry facilities, and free newspapers are also on ...
Parking was good didn't use any other services . they appear to be updating

Reviewed on Mar 14, 2026

Opens in a new windowMotel 6 Sedalia, MO
Don't see what you're looking for?
See all available properties in Syracuse
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Syracuse?
Take some of the hassles out of traveling with kids by booking a family-friendly Syracuse hotel. From well-thought-out amenities to extra-helpful services, these stays offer perks that'll help make your getaway run like a dream: You'll be well taken care of at Unique Creekside Escape - Enjoy 300+ Goats!. It comes with a barbecue grill, internet access and a commitment to making families feel at home. Also look into Western Hills Motel. It comes with a swimming pool, a picnic area and plenty of opportunities to hang out together.
Where can I find cheap hotels in Syracuse?
At Travelocity you'll find really nice hotels in Syracuse at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Syracuse rather than in Syracuse. We may find you even better rates, too.
How do I find the best Syracuse hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Syracuse then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Syracuse?
The cheapest hotel in Syracuse is $47. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Syracuse?
There are 83 hotels in Syracuse on Travelocity.
What are the best hotels in Syracuse?
Syracuse has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Syracuse for you!
When is the best time to visit Syracuse?
If you want the joy of a fun-filled trip in peak season, visit Syracuse during March, April and July. If you'd prefer the peace of off-season, book a stay during quieter months, such as August, October and December.
When is the cheapest time to stay in Syracuse?
Based on historic data is usually the cheapest month to visit Syracuse. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Syracuse?
There are multiple hotels in Syracuse that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Syracuse. We have plenty of kid-friendly hotels in Syracuse to choose from on Travelocity!
Why book a hotel in Syracuse through Travelocity?
Because we have the top hotels in Syracuse! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Syracuse on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Syracuse hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity