Explore 41 Luxury Hotels in Southwest Illinois

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Best Luxury Hotels in Southwest Illinois

Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area

910 Edwardsville Rd Troy IL
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $75 total per night from Nov 10 to Nov 11
$75 total
Nov 10 - Nov 11
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
8.2/10 Very Good! (1,001 reviews)
"Great value for the price"

Reviewed on Nov 4, 2026

Opens in a new windowSuper 8 by Wyndham Troy IL/St. Louis Area
Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL

401 S 44th St Mount Vernon IL
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $83 total per night from Nov 8 to Nov 9
$83 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel features free WiFi in public areas, free newspapers, and free self parking. Enjoy the free continental breakfast each morning. Staff at the 24-hour ...
7.8/10 Good! (1,001 reviews)
"There are multiple stores and restaurants nearby"

Reviewed on Nov 2, 2026

Opens in a new windowSuper 8 by Wyndham Mt. Vernon IL
Americas Best Value Inn West Frankfort

Americas Best Value Inn West Frankfort

1001 Factory Outlet Blvd West Frankfort IL
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $82 total per night from Nov 30 to Dec 1
$82 total
Nov 30 - Dec 1
Total with taxes and fees
This motel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. Staff at the 24-hour ...
7.6/10 Good! (541 reviews)
"Infested with rodents."

Reviewed on Oct 28, 2026

Opens in a new windowAmericas Best Value Inn West Frankfort
Super 8 by Wyndham Carbondale

Super 8 by Wyndham Carbondale

1180 E Main St Carbondale IL
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $71 total per night from Dec 2 to Dec 3
$71 total
Dec 2 - Dec 3
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Multilingual staff at the 24-hour front desk ...
Opens in a new windowSuper 8 by Wyndham Carbondale
Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL
$52 nightly
The price is $60 total per night from Nov 11 to Nov 12
$60 total
Nov 11 - Nov 12
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Opens in a new windowSuper 8 by Wyndham O'Fallon
Super 8 by Wyndham Fairview Heights-St. Louis

Super 8 by Wyndham Fairview Heights-St. Louis

45 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $69 total per night from Nov 8 to Nov 9
$69 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Opens in a new windowSuper 8 by Wyndham Fairview Heights-St. Louis
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

6 Gateway Dr Collinsville IL
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $101 total per night from Nov 22 to Nov 23
$101 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Opens in a new windowLa Quinta Inn & Suites by Wyndham Collinsville - St. Louis
Super 8 by Wyndham Salem

Super 8 by Wyndham Salem

118 Woods Lane Salem IL
Fully refundableReserve now, pay when you stay
$53 nightly
The price is $58 total per night from Nov 10 to Nov 11
$58 total
Nov 10 - Nov 11
Total with taxes and fees
This motel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free on-the-go breakfast each morning. A convenience store ...
Opens in a new windowSuper 8 by Wyndham Salem
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Southwest Illinois Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Southwest Illinois luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Southwest Illinois to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Southwest Illinois will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Southwest Illinois, and plan your next opulent escape.


Southwest Illinois hotels essential information

Accommodation
796 hotels
Lowest Price
$58
Highest Price
$101
Popular hotels
Super 8 by Wyndham Troy IL/St. Louis Area, Super 8 by Wyndham Mt. Vernon IL, Super 8 by Wyndham Carbondale, Super 8 by Wyndham O'Fallon, Super 8 by Wyndham Fairview Heights-St. Louis, La Quinta Inn & Suites by Wyndham Collinsville - St. Louis, Super 8 by Wyndham Salem, Americas Best Value Inn West Frankfort

Popular Luxury Stays in Southwest Illinois

Recent Southwest Illinois Hotel Reviews By Fellow Wanderers