Explore 211 Luxury Hotels in Southwest Coast Florida

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Best Luxury Hotels in Southwest Coast Florida

Wyvern Hotel, an Ascend Collection Hotel

101 E Retta Esplanade Punta Gorda FL

Fully refundable

$112 nightly

$125 total

Sep 27 - Sep 28

Total with taxes and fees

This smoke-free hotel features 2 restaurants and 2 bars/lounges. Traveling on business? Take advantage of the free WiFi in public areas and free internet in ...

9/10 Wonderful! (1,000 reviews)

"Everything was great, except they reception didn't explai"

Reviewed on Sep 15, 2026

LaPlaya Beach & Golf Resort - A Noble House Resort

9891 Gulf Shore Dr Naples FL

Fully refundableReserve now, pay when you stay

$514 nightly

$570 total

Sep 21 - Sep 22

Total with taxes and fees

This luxury resort features a private beach, a full-service spa, and 2 restaurants. Relax with sun loungers and beach umbrellas, and cool off with a drink at ...

9/10 Wonderful! (1,001 reviews)

"LaPlaya Beach Resort is a beautiful hotel with a great beachfront location and an overall pleasant atmosphere. We enjoyed our stay, but in my opinion, the property is somewhat overrated for the price. With rooms averaging around $800 per night, I expected a more updated and luxurious experience throughout ..."

Reviewed on Sep 17, 2026

Naples Grande Beach Resort

475 Seagate Drive Naples FL

A full-service spa, 4 restaurants, and 3 outdoor pools are all featured at this luxury resort. Enjoy beachfront dining and relax with beach cabanas and sun loungers. ...

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The Ritz-Carlton, Sarasota

1111 Ritz Carlton Dr Sarasota FL

Fully refundableReserve now, pay when you stay

$592 nightly

$669 total

Oct 18 - Oct 19

Total with taxes and fees

This smoke-free hotel features a golf course, a full-service spa, and a marina. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Enjoy ...

The Ritz-Carlton, Naples

280 Vanderbilt Beach Rd Naples FL

Fully refundableReserve now, pay when you stay

$889 nightly

$987 total

Oct 5 - Oct 6

Total with taxes and fees

A full-service spa, 5 restaurants, and 2 outdoor pools are all featured at this smoke-free resort. Relax with beach cabanas, sun loungers, and beach umbrellas. ...

Hyatt Regency Coconut Point Resort & Spa

5001 Coconut Rd Bonita Springs FL

$366 nightly

$408 total

Sep 30 - Oct 1

Total with taxes and fees

This luxury resort features free water park access, a full-service spa, and a marina. There's fun for all ages with a lazy river and a children's club, and supervised ...

The Ritz-Carlton Naples, Tiburón

2600 Tiburon Dr Naples FL

Fully refundableReserve now, pay when you stay

$449 nightly

$498 total

Sep 20 - Sep 21

Total with taxes and fees

This luxury hotel features a golf course, 4 outdoor tennis courts, and a restaurant. Take the free beach shuttle and relax with free beach cabanas and beach ...

Knickerbocker Estate: Elegant 9-BR Getaway in Naples. Enjoy Private Pool, Outdoor Dining, and Expansive Grounds, Experience Tranquility with Easy Access to Naples' Best

2225 23rd Street SW Naples FL

An outdoor pool, free self parking, and barbecue grills are featured at this villa. WiFi in public areas is free. A garden is provided and the front desk is ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Southwest Coast Florida

Pink Shell Beach Resort and Marina

275 Estero Blvd Fort Myers Beach FL

$263 nightly

$293 total

Sep 28 - Sep 29

Total with taxes and fees

9.4/10 Exceptional! (1,439 reviews)

5 star hotels in Southwest Coast Florida

Sundial Beach Resort & Spa

1451 Middle Gulf Drive Sanibel FL

$398 nightly

$444 total

Sep 20 - Sep 21

Total with taxes and fees

8.6/10 Excellent! (2,699 reviews)

Southwest Coast Florida Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Southwest Coast Florida luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Southwest Coast Florida to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Southwest Coast Florida will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Southwest Coast Florida, and plan your next opulent escape.

Southwest Coast Florida hotels essential information

Accommodation	47,287 hotels
Lowest Price	$125
Highest Price	$987
Popular hotels	Wyvern Hotel, an Ascend Collection Hotel, Naples Grande Beach Resort, The Ritz-Carlton, Sarasota, The Ritz-Carlton, Naples, Hyatt Regency Coconut Point Resort & Spa, The Ritz-Carlton Naples, Tiburón, LaPlaya Beach & Golf Resort - A Noble House Resort, Knickerbocker Estate: Elegant 9-BR Getaway in Naples. Enjoy Private Pool, Outdoor Dining, and Expansive Grounds, Experience Tranquility with Easy Access to Naples' Best