Explore 13 Luxury Hotels in Southeast Illinois
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Best Luxury Hotels in Southeast Illinois

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
"Hotel was very clean and well maintained"
Reviewed on Nov 3, 2026

Rodeway Inn Effingham North

Days Inn by Wyndham Effingham

Holiday Inn Express & Suites Mattoon by IHG

Quality Inn Effingham North

Days Inn & Suites by Wyndham Casey

Days Inn by Wyndham Charleston

Ramada by Wyndham Effingham
Southeast Illinois Luxury Hotels
Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Southeast Illinois luxury hotels are the plush oasis you’ve been looking for.
Choose from the best luxury hotels in Southeast Illinois to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.
We want you to enjoy your next vacation in style and the top luxury resorts in Southeast Illinois will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Southeast Illinois, and plan your next opulent escape.
Southeast Illinois hotels essential information
Accommodation | 422 hotels |
|---|---|
Lowest Price | $69 |
Highest Price | $130 |
Popular hotels | Rodeway Inn Effingham North, Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination, Days Inn by Wyndham Effingham, Holiday Inn Express & Suites Mattoon by IHG, Quality Inn Effingham North, Days Inn & Suites by Wyndham Casey, Days Inn by Wyndham Charleston, Ramada by Wyndham Effingham |
Popular Luxury Stays in Southeast Illinois
Recent Southeast Illinois Hotel Reviews By Fellow Wanderers

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
"Hotel was very clean and well maintained"




