Hotels on the Lake in South Carolina Midlands from $64
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top South Carolina Midlands Hotels on the Lake

The Inn at the Crossroads
128 West Main Street Lake City SC
Free Cancellation
Reserve now, pay when you stay
$116 nightly
The price is $130 total per night
$130 total
Dec 6 - Dec 7
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

Hampton Inn Columbia I-26/Harbison Blvd.
101 Woodcross Dr Columbia SC
Free Cancellation
Reserve now, pay when you stay
$102 nightly
The price is $114 total per night
$114 total
Dec 6 - Dec 7
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...

Residence Inn by Marriott Columbia Northwest/Harbison
944 Lake Murray Blvd Irmo SC
Free Cancellation
Reserve now, pay when you stay
$101 nightly
The price is $113 total per night
$113 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling for business? Take advantage of the free WiFi in public areas, express check-out, and conference ...

Holiday Inn Express Columbia West - Lexington by IHG
108 Saluda Pointe Court Lexington SC
Free Cancellation
$105 nightly
The price is $117 total per night
$117 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...

Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr Columbia SC
Free Cancellation
Reserve now, pay when you stay
$85 nightly
The price is $96 total per night
$96 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

Quality Inn Fort Mill near Carowinds Blvd.
3560 Lakemont Blvd Fort Mill SC
Free Cancellation
$58 nightly
The price is $64 total per night
$64 total
Nov 25 - Nov 26
Total with taxes and fees
A seasonal outdoor pool, free parking, and free newspapers are featured at this hotel. There's no skimping on freebies - guests receive free buffet breakfast, ...

Country Inn & Suites by Radisson, Columbia at Harbison, SC
414 Piney Grove Road Columbia SC
Free Cancellation
$66 nightly
The price is $71 total per night
$71 total
Nov 25 - Nov 26
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate freebies like continental ...

Red Roof Inn Santee
9091 Old Hwy 6 Santee SC
Free Cancellation
Reserve now, pay when you stay
$63 nightly
The price is $70 total per night
$70 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...

Motel 6 West Columbia, SC - Airport
650 Cherokee Lane West Columbia SC
Free Cancellation
$65 nightly
The price is $70 total per night
$70 total
Nov 8 - Nov 9
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A picnic area, laundry facilities, and barbecue grills are also on ...

Best Western Plus Santee Inn
I 95 Exit 98 Santee SC
Free Cancellation
Reserve now, pay when you stay
$119 nightly
The price is $132 total per night
$132 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...

Hampton Inn Santee-I-95
9060 Old Number Six Hwy Santee SC
Free Cancellation
Reserve now, pay when you stay
$123 nightly
The price is $137 total per night
$137 total
Nov 25 - Nov 26
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Guests will appreciate free perks like free self parking and WiFi in public areas. A 24-hour business ...
Don't see what you're looking for?
See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
South Carolina Midlands hotels essential information
Accommodation | 3,402 hotels |
|---|---|
Lowest Price | $64 |
Highest Price | $137 |
Popular hotels | Hampton Inn Columbia I-26/Harbison Blvd., Red Roof Inn Santee, Motel 6 West Columbia, SC - Airport, The Inn at the Crossroads, Residence Inn by Marriott Columbia Northwest/Harbison, Country Inn & Suites by Radisson, Columbia at Harbison, SC, Best Western Plus Santee Inn, Holiday Inn Express Columbia West - Lexington by IHG, Hampton Inn Santee-I-95, Quality Inn Fort Mill near Carowinds Blvd., Hilton Garden Inn Columbia/Harbison |
More ways to wander South Carolina Midlands
Flights to South Carolina Midlands
The best fares to get you there
South Carolina Midlands Hotels
South Carolina Midlands Vacation Rentals
Great Deals on Alternative Accommodations
South Carolina Midlands Car Rentals
Affordable cars to get you around town
South Carolina Midlands Vacations
Save more by combining flights, hotels and cars
