Hotels on the Lake in South Carolina Midlands from $65 total
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Top South Carolina Midlands Hotels on the Lake

The Inn at the Crossroads
128 West Main Street, Lake City, SC
Free Cancellation
Reserve now, pay when you stay
$166 nightly
The price is $186 total per night
$186 total
May 25 - May 26
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

Hampton Inn Santee-I-95
9060 Old Number Six Hwy, Santee, SC
Free Cancellation
Reserve now, pay when you stay
$136 nightly
The price is $151 total per night
$151 total
May 26 - May 27
Total includes taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Guests will appreciate free perks like free self parking and WiFi in public areas. A 24-hour business ...

Residence Inn by Marriott Columbia Northwest/Harbison
944 Lake Murray Blvd, Irmo, SC
Free Cancellation
Reserve now, pay when you stay
$98 nightly
The price is $108 total per night
$108 total
Jun 8 - Jun 9
Total includes taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...

Hampton Inn Columbia I-26/Harbison Blvd.
101 Woodcross Dr, Columbia, SC
Free Cancellation
Reserve now, pay when you stay
$101 nightly
The price is $113 total per night
$113 total
May 25 - May 26
Total includes taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...

Wingate by Wyndham Columbia / Lexington
108 Saluda Pointe Ct, Lexington, SC
Free Cancellation
Reserve now, pay when you stay
$117 nightly
The price is $130 total per night
$130 total
May 30 - May 31
Total includes taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...

Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr, Columbia, SC
Free Cancellation
Reserve now, pay when you stay
$84 nightly
The price is $94 total per night
$94 total
May 25 - May 26
Total includes taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

Best Western Plus Santee Inn
I 95 Exit 98, Santee, SC
Free Cancellation
Reserve now, pay when you stay
$111 nightly
The price is $123 total per night
$123 total
Jun 15 - Jun 16
Total includes taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...

Motel 6 West Columbia, SC - Airport
650 Cherokee Lane, West Columbia, SC
Free Cancellation
Reserve now, pay when you stay
$93 nightly
The price is $100 total per night
$100 total
May 17 - May 18
Total includes taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A picnic area, laundry facilities, and barbecue grills are also on ...

Quality Inn at the Park
3560 Lakemont Blvd, Fort Mill, SC
Free Cancellation
Reserve now, pay when you stay
$59 nightly
The price is $65 total per night
$65 total
Jun 8 - Jun 9
Total includes taxes and fees
A seasonal outdoor pool, free parking, and free newspapers are featured at this hotel. There's no skimping on freebies - guests receive free buffet breakfast, ...

Red Roof Inn Santee
9091 Old Hwy 6, Santee, SC
Free Cancellation
Reserve now, pay when you stay
$67 nightly
The price is $74 total per night
$74 total
Jun 1 - Jun 2
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...

Country Inn & Suites by Radisson, Columbia at Harbison, SC
414 Piney Grove Road, Columbia, SC
Free Cancellation
$76 nightly
The price is $82 total per night
$82 total
May 19 - May 20
Total includes taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. A lobby fireplace, ...

Days Inn by Wyndham Columbia
1144 Bush River Rd, Columbia, SC
Free Cancellation
Reserve now, pay when you stay
$64 nightly
The price is $72 total per night
$72 total
May 18 - May 19
Total includes taxes and fees
This motel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
South Carolina Midlands hotels essential information
Accommodation | 2,878 hotels |
---|---|
Lowest Price | $65 total |
Highest Price | $186 total |
Popular hotels | Hampton Inn Columbia I-26/Harbison Blvd., Days Inn by Wyndham Columbia, Red Roof Inn Santee, Motel 6 West Columbia, SC - Airport, The Inn at the Crossroads, Residence Inn by Marriott Columbia Northwest/Harbison, Country Inn & Suites by Radisson, Columbia at Harbison, SC, Best Western Plus Santee Inn, Wingate by Wyndham Columbia / Lexington, Hampton Inn Santee-I-95, Quality Inn at the Park, Hilton Garden Inn Columbia/Harbison |
Recent South Carolina Midlands hotel reviews by fellow wanderers

Hilton Garden Inn Columbia/Harbison
5 out of 5
Posted 19 hours ago
Travelocity Verified Review
"Great staff and excellent restaurant "
A verified traveler from Blythewood stayed at Hilton Garden Inn Columbia/Harbison

Sleep Inn Columbia
5 out of 5
Posted 4 days ago
Travelocity Verified Review
"We have stayed here several times for USC events. It is clean, beds are comfy, staff are kind and attentive. It is a bit outdated, but don’t let that turn you off. It’s CLEAN. That’s my one thing I will not cave for. I don’t want bugs, and after 5 stays, we’ve never experienced any. We’ve stayed at higher end hotels and have had horrible experiences. There’s a small breakfast in the am that’s free.
There are have been instances of excessive noise, but we go in expecting it’s a hotel and not a private apartment, and also easily addressed.
If you’re a parent or friend visiting USC, it’s a 15 min drive to campus or about 15-20 dollar Uber.
Their prices are reasonable ( even for grad weekend) and are genuinely very kind people that own and run the hotel. We had 13 people stay there this past weekend with no complaints. "
A verified traveler stayed at Sleep Inn Columbia
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