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Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

3.0 star property
3-star hotel near Denny Sanford Premier Center

Choose dates to view prices

Photo gallery for Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

Terrace/patio
Indoor pool
Fridge, microwave, dishwasher, coffee/tea maker
Studio Suite, 1 King Bed, Non Smoking | Living area | LCD TV
Suite, 1 Bedroom, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Pool
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning

Explore the area

View in a map
1120 S Grange Ave, Sioux Falls, SD, 57105
  • Place, University of Sioux Falls
    ‪5 min walk‬
  • Place, Augustana College
    ‪11 min walk‬
  • Place, Washington Pavilion of Arts and Science
    ‪3 min drive‬
  • Airport, Sioux Falls, SD (FSD-Sioux Falls Regional)
    ‪10 min drive‬

Room options

View all photos for Studio Suite, 1 King Bed, Non Smoking

Studio Suite, 1 King Bed, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi

Studio Suite, 1 King Bed, Non Smoking

9.4 out of 10
Exceptional
(27 reviews)
  • 435 sq ft
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Studio, 2 Queen Beds, Non Smoking

Studio, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi

Studio, 2 Queen Beds, Non Smoking

9.4 out of 10
Exceptional
(12 reviews)
  • 435 sq ft
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

View all photos for Suite, 1 Bedroom, Non Smoking

Suite, 1 Bedroom, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi

Suite, 1 Bedroom, Non Smoking

10.0 out of 10
Exceptional
(2 reviews)
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Studio, 1 King Bed, Accessible, Non Smoking

Desk, blackout drapes, iron/ironing board, free WiFi

Studio, 1 King Bed, Accessible, Non Smoking

7.4 out of 10
Good
(3 reviews)
  • 435 sq ft
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Studio, 1 King Bed, Accessible, Bathtub

Desk, blackout drapes, iron/ironing board, free WiFi

Studio, 1 King Bed, Accessible, Bathtub

9.6 out of 10
Exceptional
(4 reviews)
  • 430 sq ft
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Studio, 2 Queen Beds, Accessible, Non Smoking

Desk, blackout drapes, iron/ironing board, free WiFi

Studio, 2 Queen Beds, Accessible, Non Smoking

9.0 out of 10
Wonderful
(4 reviews)
  • 435 sq ft
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

View all photos for Studio, 2 Queen Beds, Accessible, Bathtub

Desk, blackout drapes, iron/ironing board, free WiFi

Studio, 2 Queen Beds, Accessible, Bathtub

9.0 out of 10
Wonderful
(2 reviews)
  • 435 sq ft
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

View all photos for Studio, 2 Queen Beds, Accessible, Non Smoking

Desk, blackout drapes, iron/ironing board, free WiFi

Studio, 2 Queen Beds, Accessible, Non Smoking

9.2 out of 10
Wonderful
(5 reviews)
  • 435 sq ft
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

View all photos for Suite, 1 King Bed, Accessible, Bathtub

Desk, blackout drapes, iron/ironing board, free WiFi

Suite, 1 King Bed, Accessible, Bathtub

10.0 out of 10
Exceptional
(1 review)
  • 527 sq ft
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 King Bed, Accessible, Non Smoking

Desk, blackout drapes, iron/ironing board, free WiFi

Suite, 1 King Bed, Accessible, Non Smoking

  • 530 sq ft
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 King Bed, Accessible, Non Smoking

Desk, blackout drapes, iron/ironing board, free WiFi

Suite, 1 King Bed, Accessible, Non Smoking

  • 530 sq ft
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

King Studio Suite-Non-Smoking

  • Sleeps 4
  • Free WiFi

King Suite-Accessible Roll In Shower-Non-Smoking

  • Sleeps 4
  • Free WiFi

One-Bedroom King Suite-Non-Smoking

  • Sleeps 4
  • Free WiFi

View all photos for Studio With 2 Queen Beds-Non-Smoking

Towels

Studio With 2 Queen Beds-Non-Smoking

  • Sleeps 6
  • Free WiFi

Mobility Hearing Access King Suite with tub

  • Sleeps 4
  • Free WiFi

View all photos for hearing Access King Studio Suite

Towels

hearing Access King Studio Suite

  • Sleeps 4
  • Free WiFi

Hearing Access Two Queen Studio Suite

  • Sleeps 6
  • Free WiFi

Access Two Queen Studio with Roll in Shower

  • Sleeps 6
  • Free WiFi

Access Two Queen Studio with Tub

  • Sleeps 6
  • Free WiFi

King Studio Suite With Accessible Tub-Non-Smoking

  • Sleeps 4
  • Free WiFi

King Suite-Hearing Accessible-Non-Smoking

  • Sleeps 4
  • Free WiFi

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Hilton Garden Inn Sioux Falls South

South Sioux Falls
  • Pool
  • Hot tub
  • Pet friendly
  • Parking included
4.4 out of 5, Excellent, 729 reviews
$97 nightly
The price is $108
May 10 - May 11
Total with taxes and fees
Hilton Garden Inn Sioux Falls South

About the neighborhood

Sioux Falls

University Heights stay.A stay at this University Heights hotel places you steps from Sanford USD Medical Center and within a 5-minute walk of Sioux Empire Medical Museum. University of Sioux Falls and Augustana College are also within half a mile (1 km).

What's nearby

  • University of Sioux Falls - 5 min walk - 0.3 miles
  • Augustana College - 11 min walk - 0.6 miles
  • Washington Pavilion of Arts and Science - 3 min drive - 1.1 miles
  • Great Plains Zoo - 3 min drive - 1.4 miles
  • Falls Park - 4 min drive - 1.5 miles

Getting around

  • Sioux Falls Regional Airport (FSD) - 8 min drive

Restaurants

  • ‪Casey's - ‬12 min walk
  • ‪Fryn' Pan - ‬2 min drive
  • ‪Taco Bell - ‬13 min walk
  • ‪Taco John's - ‬3 min drive
  • ‪Perch - ‬18 min walk

About this property

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

3-star hotel near Denny Sanford Premier Center
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center offers its guests an indoor pool and a 24-hour fitness center. WiFi is free in public spaces. You'll find a business center on site. Free breakfast is served daily. Event space at this hotel measures 950 square feet (86 square meters) and includes conference space. The business-friendly Home2 Suites By Hilton Sioux Falls/Sanford Medical Center also features barbecue grills, laundry facilities, and express check-out. Free self parking is available.

Smoking is allowed in designated areas at this 3-star Sioux Falls hotel.

  • 1 building
  • 80 guestrooms or units
  • 4 levels
  • 950 sq ft of conference space
  • 86 sq m of conference space
  • Built in 2014
  • To-go breakfast (free)
  • Business facilities
  • Conference space
  • Self-service laundry
  • Front desk (24 hours)
  • Express check-out
  • Storage area for luggage
  • Front-desk safe
  • BBQ grill(s)
  • Elevator
  • Smoking in designated areas
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center offers 80 accommodations with coffee/tea makers and irons/ironing boards. Accommodations are furnished with double sofa beds. LCD televisions are featured in guestrooms. Accommodations at this 3-star hotel have kitchens with refrigerators, microwaves, cookware/dishes/utensils, and dishwashers.

This Sioux Falls hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and phones. Housekeeping is provided weekly.

Similar properties

Terrace/patio
Hyatt Place Sioux Falls South
Mall District
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
4.7 out of 5, Exceptional, 1,001 reviews
$117 nightly
The price is $130
May 10 - May 11
Total with taxes and fees
Hyatt Place Sioux Falls South

Property amenities

Family friendly

  • In-room kitchen
  • In-room microwave
  • In-room refrigerator
  • In-room sofa bed
  • Indoor pool
  • Laundry facilities
  • Living room

Internet

  • Available in all rooms: Free WiFi
  • Free in-room WiFi has a 3-device limit
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free on-the-go breakfast available daily 6:00 AM to 9:00 AM

Things to do

  • 24-hour gym
  • Indoor pool

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Braille/raised signage
  • Elevator
  • Phone accessibility kit
  • Stair-free path to entrance
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible van parking

Room amenities

Entertainment

  • 42-inch LCD TV

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Double sofa bed

Bathroom

  • Private bathroom
  • Toothbrush and toothpaste (on request)
  • Towels provided

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dishwasher
  • Kitchen
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Iron/ironing board
  • Living room
  • Phone

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: 11:00 PM
Early check-in subject to availability
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before noon
Contactless check-out available
Late check-out subject to availability
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
This property doesn't offer after-hours check-in
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Pets: USD 50 per accommodation, per stay
  • Only dogs and cats are allowed
  • Maximum 2 (weight limit: 50 lbs per pet)
  • Service animals are exempt from fees

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cribs (infant beds) are not available.

Property payment types

Important information

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Pet fee: USD 50 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards, debit cards, and cash
Noise-free guestrooms cannot be guaranteed
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. This property accepts Visa, Mastercard, American Express, Discover, Diners Club, JCB International, debit cards, and cash. Noise-free guestrooms cannot be guaranteed.

We should mention

  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • Free in-room WiFi has a 3-device limit.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Home2 Suites Hilton Sioux Falls/Sanford Hotel
Home2 Suites Hilton Falls/Sanford Hotel
Home2 Suites Hilton Sioux Falls/Sanford
Home2 Suites Hilton Sioux Falls/Sanford Hotel
Home2 Suites Hilton Falls/Sanford Hotel
Home2 Suites Hilton Sioux Falls/Sanford
Home2 Suites Hilton Falls/Sanford
Hotel Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center Hotel

Frequently asked questions

How close is Home2 Suites By Hilton Sioux Falls/Sanford Medical Center to the airport?

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center is 4 mi (8-min drive) away from the Sioux Falls Regional Airport (FSD) airport, the closest popular airport to the property.

How much does it cost to stay at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

As of Apr 30, 2026, prices found for a 1-night stay for 2 adults at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center on May 24, 2026 start from $128, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does Home2 Suites By Hilton Sioux Falls/Sanford Medical Center have an airport shuttle?

Airport shuttle services are not available at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center.

How close is Home2 Suites By Hilton Sioux Falls/Sanford Medical Center to the beach?

This hotel is 13.1 mi (27-min drive) from Lake Alvin Beach.

Does Home2 Suites By Hilton Sioux Falls/Sanford Medical Center offer free breakfast?

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center offers free on-the-go breakfast every day from 6 AM to 9 AM.

Is there a casino at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

No, there is no casino at this hotel, but Grand Falls Casino Resort (21-min drive) is nearby.

What time is check-in at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

Check-in start time: 3:00 PM; Check-in end time: 11:00 PM.

Is there free parking at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

This hotel offers free self parking.

Does Home2 Suites By Hilton Sioux Falls/Sanford Medical Center have a pool?

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center features an indoor pool.

Does Home2 Suites By Hilton Sioux Falls/Sanford Medical Center have a spa?

There are no spa services available at this hotel.

How close is Home2 Suites By Hilton Sioux Falls/Sanford Medical Center to downtown Sioux Falls?

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center is 0.8 mi away from Sioux Falls.

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 480 out of 633 reviews
Rating 8 - Good. 109 out of 633 reviews
Rating 6 - Okay. 26 out of 633 reviews
Rating 4 - Poor. 9 out of 633 reviews
Rating 2 - Terrible. 9 out of 633 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.2/10

Amenities

9.6/10

Property conditions & facilities

Reviews

10/10 Excellent

Lucas

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Spotless, spacious, well stocked room that smelled good.
Stayed 1 night in Jan 2026

10/10 Excellent

Kathleen

Business traveler
Liked: Cleanliness, amenities, property conditions & facilities
The room was spotless and the staff was very efficient and personable
Stayed 1 night in Jan 2026

10/10 Excellent

Andrew

Liked: Cleanliness, staff & service, property conditions & facilities
Convenient skybridge to hospital
Stayed 4 nights in Jan 2026

10/10 Excellent

Kathleen

Stayed 1 night in Jan 2026

10/10 Excellent

Lance

Liked: Cleanliness, amenities, property conditions & facilities
Quiet, clean room
Stayed 1 night in Jan 2026

10/10 Excellent

Shyanne

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Staff was very friendly, rooms were clean. The stay was amazing
Stayed 1 night in Jan 2026

10/10 Excellent

Mindy

Stayed 1 night in Jan 2026

10/10 Excellent

Natalie

Liked: Cleanliness, staff & service, property conditions & facilities
Clean room | Breakfast Great | Wonderful and Helpful Staff
Stayed 4 nights in Dec 2025

10/10 Excellent

Melanie

Stayed 1 night in Dec 2025

10/10 Excellent

Kim

Traveled with partner
Liked: Cleanliness, property conditions & facilities
The staff was so wonderful! Destynee was so kind, her smile just lifted my spirits. The room was comfortable and spotless. Would definitely stay here again!
Stayed 1 night in Dec 2025

10/10 Excellent

Robert

Stayed 2 nights in Dec 2025

10/10 Excellent

tricia

Stayed 1 night in Dec 2025

10/10 Excellent

Monty

Stayed 1 night in Dec 2025

10/10 Excellent

Tom

Stayed 1 night in Dec 2025

10/10 Excellent

Halee

Stayed 1 night in Dec 2025

8/10 Good

Hans

Business traveler
Liked: Cleanliness, staff & service, amenities
good
Stayed 2 nights in Dec 2025

6/10 Okay

Katie

Stayed 2 nights in Dec 2025

2/10 Terrible

Austin

Stayed 1 night in Dec 2025

8/10 Good

rhonda, huron

Business traveler, Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Extremely convenient and well maintained property.
Stayed 1 night in Dec 2025

8/10 Good

SEAN

Liked: Cleanliness, amenities, property conditions & facilities
YES EVERYTHING WAS OKAY EXCEPT PARKING CHARGE YOU MUST GIVE US CREDIT FOR $70.00 FOR PARKING REGLAR GUEST THE BOOK DIRECT FROM HOTEL THEY HAD PARKING FREE ALSO LEES HOTEL COST
Stayed 7 nights in Nov 2025

10/10 Excellent

Tracey

Liked: Cleanliness, staff & service, property conditions & facilities
This is a great hotel - centrally located and very clean and quiet. Will definitely be staying there again.
Stayed 2 nights in Nov 2025

8/10 Good

Mary

Stayed 1 night in Dec 2025

10/10 Excellent

Drew

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Great stay, love the skybridge to the hospital!
Stayed 5 nights in Nov 2025

10/10 Excellent

Cynthia

Liked: Property conditions & facilities
Great!
Stayed 2 nights in Nov 2025

10/10 Excellent

Diane

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Staff was very friendly, room was clean
Stayed 1 night in Nov 2025