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Top Santa Isabel hotels

Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Over the Water Cabin on San Blas Island
Reviewed on Feb 16, 2022

San Blas Paradise Private Cabins on Shipwreck Island - meals included

Cabins in Asserya Island - San Blas paradise - meals included

Paradise Over the Water Cabins in San Blas
Reviewed on Sep 4, 2022

BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES
Reviewed on Jan 31, 2025

Caribbean Paradise - Beachfront Getaway
Reviewed on Jun 23, 2025

- SV La Francesca - san blas paradise on bord of private sailboat

Cabins on paradise San Blas island
Santa Isabel Hotel & Travel Guide\n
You'll know there's just 1 accommodation option within a convenient driving distance of Santa Isabel's center, so you should consider booking somewhere to sleep as soon as you can.
The Coral Lodge is the nearest Travelocity accommodation option to the heart of Santa Isabel and it is located a simple and brief drive away.
When you reach downtown Santa Isabel, it is about 17 miles (27 kilometers) to the Coco Blanco.
Panama City is 45 miles (69 kilometers) to the southwest of Santa Isabel and is home to Bridge of the Americas and Miraflores Locks. A few Travelocity-recommended Panama City places to base yourself include the InterContinental Miramar Panama and Trump Ocean Club International Hotel and Tower Panama. 55 miles (87 kilometers) west of Santa Isabel, you'll reach Colon, which is home to the Radisson Colon 2,000 Hotel & Casino and Four Points By Sheraton Colon. While in Colon, set aside a little time to check out the Gatun Locks and Colon Free Zone.
When sport is never far from your mind, make the trip to Estadio Rommel Fernandez, located 40 miles (65 kilometers) to the southwest of Santa Isabel. Book a Travelocity-listed hotel right by the sporting action at the The Westin Panama or the Courtyard Panama at Metromall Mall.
Tocumen International Airport can be found 35 miles (57 kilometers) from Santa Isabel's downtown area. Enlightened travelers who hope to find a close base can book a night at the Riande Aeropuerto Hotel & Casino or the Express Inn Panama International Airport Hostel.
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Recent Santa Isabel hotel reviews by fellow wanderers

Caribbean Paradise - Beachfront Getaway
