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Save up to $413 | Book Flight + Hotel at the same time^
Save up to $413 | Book Flight + Hotel at the same time^
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Save up to $413 | Book Flight + Hotel at the same time^

Santa Ana Vacations

Santa Ana Vacations

Get your travels off to the best possible start by knowing a thing or two about Santa Ana before you jet off.

From the center of Panama City, you'll need to make your way southwest for 2 miles (3 kilometers) to reach this neighborhood.

Santa Ana Vacation Packages

With Travelocity, you'll score an amazing bargain if you lock in a flight and accommodation package deal. You can also pick from more than 400 partner airlines and 665,000 lodging options.

From airfares and accommodations to activities and car rentals, you've got the security of 24/7 personal assistance via our Customer 1st Guarantee. Seen an even better bargain? We'll match the price and reimburse the difference^.

You can never predict if a circumstance will change. However, if you purchase a package, we guarantee that there'll be no cancellation fees from us. And as long as you get in quick, many accommodations don't charge extra fees either^.

Hotels in Santa Ana

Wander wisely in Santa Ana by staying somewhere close by. This lovely neighborhood has 24 properties to select from within walking distance.

Check out the Las Clementinas (Casco Antiguo, Calle 11 Y Ave B) and the American Trade Hotel (Plaza Herrera Casco Viejo). Our top Santa Ana picks, they offer a wonderful night's sleep in a handy location.

Where do you fly into for Santa Ana?

Landing at Tocumen International Airport (PTY)? Santa Ana is only 13 miles (21 kilometers) from here. Grab a coffee, hail down a cab and you'll be there in no time at all!

Can I rent a car in Santa Ana?

Thinking about taking a road trip during your stay in Santa Ana? A rental car will surely be helpful here. Look through some of the options on Travelocity, select your favorite and start organizing your road trip playlist!

Getting in by plane? Fox Rental Cars at Tocumen International Airport is the vendor to visit after collecting your baggage.

Budget is located in the middle of the city at Tocumen International Airport. This makes it an easy option for those staying central.

Places to visit in Santa Ana

Metropolitan Cathedral of Panama is one of this area's most notable attractions — and best of all, it's a very short drive from the center of town.

Boasting numerous fascinating exhibits, collections and programs, Museum of Natural Science inspires, educates and entertains the curious visitors who stream through its doors.

Seeking more nearby options?

You'll enjoy exploring Independence Square, a historic piazza that attracts locals and visitors alike.

But that's not all there is.

Make a point of stopping to see and learn the background of Palacio de las Garzas, a historic civic building.

Places to Visit Near Santa Ana

El Chorrillo and Casco Viejo are well worth a visit while you are here. El Chorrillo is approximately 0.6 miles (1 kilometer) away, while Casco Viejo is 0.6 miles (1 kilometer) away.

^Terms and conditions apply.

Top Santa Ana Hotels Deals

$28
Hotel Doral

Hotel Doral

2.5 out of 5.0 Calle Monteserin, adjacent to the National Institute, Panama City
2/5
(1 Reviews)
A coffee shop, free WiFi in public areas, and dry cleaning are available at this hotel. Luggage storage is provided and the front desk is staffed around-the-clock.
$49
Selina Casco Viejo

Selina Casco Viejo

3.5 out of 5.0 Av. B, Panama City, Panamá
The hotel's outdoor pool, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Enjoy a meal from the restaurant and perks like free WiFi. A business center, a grocery/convenience store, and a communal living room are also on offer.
$14
Hotel República

Hotel República

2.0 out of 5.0 Plaza 5 De Mayo Final Ave, Panama City, Panama
An area shuttle is featured at this hotel, along with a rooftop terrace and a 24-hour front desk. WiFi in public areas is free. Concierge services are provided for your convenience.
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Hotel Riazor

Hotel Riazor

2.5 out of 5.0 Calle 16 Oeste, Santa Ana, Panamá, Panama City, Panama (province)
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Self parking is offered and the front desk is staffed around-the-clock.

Things to do in Santa Ana

See all 229 things to do in Santa Ana

Top Flight Deals to Santa Ana

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

^Savings based on all package bookings made with Flight + Hotel on Travelocity.com from January 1, 2018 to December 31, 2018, as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.