
Deals on vacations and trips to Santa Ana
Santa Ana flight + hotel vacation packages
Price found within the past 48 hours. Click for updated prices.

Hotel Panamonte
Save 100% on your flight
Price was $1,080, price is now $685 per person
$685
per person
Nov 28 - Dec 3
found 7 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
A restaurant and a bar/lounge are featured at this hotel. Guests will appreciate free perks like free self parking and WiFi in public areas. You'll appreciate the area shuttle, terrace, and garden.

Central Hotel Bocas del Toro
Save 100% on your flight
Price was $1,803, price is now $950 per person
$950
per person
Jan 3 - Jan 6
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
A marina and a restaurant are featured at this hotel. Enjoy the outdoor pool and free perks like continental breakfast and WiFi in public areas. A bar/lounge, a 24-hour front desk, and dry cleaning are also provided.


Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
Price was $2,076, price is now $1,277 per person
$1,277
per person
Dec 24 - Dec 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.

Casa Mallet by Wynwood House
Casco Viejo
Save 100% on your flight
Price was $2,272, price is now $1,511 per person
$1,511
per person
Dec 24 - Dec 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Free WiFi in public areas is available at this apartment. Take advantage of the self parking.
Top Santa Ana hotels deals

Casco View Apartments
C. 16 Oeste, Panama City, Provincia de Panamá
An outdoor pool is featured at this condo, along with a terrace and a garden. Staff at the 24-hour front desk can provide around-the-clock assistance.
Pool
Kitchen

Hotel Riu Plaza Panama
Calle 50, Urb. Marbella, Panama City, Panama
Free Cancellation
Reserve now, pay when you stay
$106 nightly
The price is $117 total per night
$117 total
Nov 19 - Nov 20
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Relax with a drink at the bar/lounge and enjoy the free buffet breakfast each morning.
Pool
Breakfast included

Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
Free Cancellation
$121 nightly
The price is $133 total per night
$133 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool, onsite laundry facilities, and babysitting. Enjoy the 24-hour gym and perks like free WiFi and a free airport shuttle.
Pool
Free airport shuttle

Dreams Playa Bonita Panama - All Inclusive
KM 7, Road to Veracruz, Veracruz, Panama
Free Cancellation
Reserve now, pay when you stay
$290 nightly
The price is $290 total per night
$290 total
Nov 18 - Nov 19
Total with taxes and fees
A full-service spa, a nightclub, and 4 outdoor pools are all featured at this all-inclusive property. Spend a day at the beach kayaking, or relax with free beach cabanas and sun loungers. There's fun for all ages with a free kid's club and mini golf, and in-room childcare is an added bonus.
Pool
Breakfast included

Megapolis Hotel Panamá
Avenida Balboa, Panama City
Free Cancellation
Reserve now, pay when you stay
$125 nightly
The price is $138 total per night
$138 total
Oct 24 - Oct 25
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and free self parking.
Pool
Hot Tub

Marriott Panama Hotel
Roosevelt Ave., Allbrook Mall, Panama City, Panama
Free Cancellation
Reserve now, pay when you stay
$134 nightly
The price is $148 total per night
$148 total
Nov 7 - Nov 8
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the a rooftop terrace and visit the 2 bars/lounges and poolside bar for drinks.
Pool
Pet friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit

Multiplaza Pacific Mall
4.5/5(634 reviews)
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Cinta Costera
4.5/5(456 reviews)
Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Avenida Balboa
4/5(554 reviews)
You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.
Frequently asked questions
Photos of local treasures
Browse Santa Ana vacation photos for more inspiration