Book Hotels in Pythagorio
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top Pythagorio hotels

Doryssa Lithos Hotel
Pythagorion Samos
$137 nightly
The price is $153 total per night from May 15 to May 16
$153 total
May 15 - May 16
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and a seasonal outdoor pool. Guests will appreciate free perks like cooked-to-order breakfast and WiFi in public ...
This property was ideally located above the port of pythagorion. Service was super friendly, staff charming with wonderful breakfasts by the pool included. They work hard to keep the property spotless and we'll maintained. Highly recommend.
Reviewed on Oct 13, 2025

Casa Cook Samos
Potokaki, Pythagorion Samos
Fully refundableReserve now, pay when you stay
$221 nightly
The price is $259 total per night from May 10 to May 11
$259 total
May 10 - May 11
Total with taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Enjoy beachfront dining and relax with free beach cabanas and sun loungers. ...
Clean and modernly decorated rooms with all the facilities
Reviewed on Oct 31, 2025

Proteas Blu Resort - Adults Only
Pythagorion Samos Samos Island
$285 nightly
The price is $330 total per night from May 4 to May 5
$330 total
May 4 - May 5
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and 3 restaurants. Relax with sun loungers and beach umbrellas, and cool off with a drink at ...
Perfect
Reviewed on Sep 23, 2025

Mykali
Pythagorion Samos North Aegean Islands
This hotel features a restaurant, an outdoor pool, and a poolside bar. Guests will appreciate free perks like free self parking and WiFi in public areas. A terrace, ...
The staff made our stay a remembrance. Thank you.
Reviewed on Jun 26, 2025

Doryssa Method Hotel
Pythagoreio, 83103 Samos Samos
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $132 total per night from May 10 to May 11
$132 total
May 10 - May 11
Total with taxes and fees
This hotel features free WiFi in public areas, luggage storage, and concierge services. Enjoy the free continental breakfast each morning. Staff at the 24-hour ...
Great hotel
Reviewed on Aug 18, 2025

Doryssa Boutique Hotel
Pythagoreio Samos Samos Island
$172 nightly
The price is $194 total per night from May 13 to May 14
$194 total
May 13 - May 14
Total with taxes and fees
This hotel features a restaurant, a gym, and a poolside bar. Enjoy the seasonal outdoor pool and free perks like buffet breakfast and free self parking. Free ...
-
Reviewed on Oct 3, 2025

Doryssa Seaside Resort
Pythagoreiou-Choras Samos Samos Island
Fully refundableReserve now, pay when you stay
$174 nightly
The price is $208 total per night from May 2 to May 3
$208 total
May 2 - May 3
Total with taxes and fees
A full-service spa, 2 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Enjoy beachfront dining and relax with sun loungers and beach ...
Clean and comfortable
Only really used the hotel for getting ready and to sleep, so can’t really comment too much. Hotel was comfortable and clean. Breakfast was good and it has a nice pool area with big comfy sunbeds. We were only there for 3 days, so spent most of our time sightseeing.
Reviewed on Jun 28, 2025

Sunrise Hotel
Ireon Samos Samos Island
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. There's no skimping on freebies - guests receive free breakfast (local cuisine), free ...
They didn't have a room so they "upgraded " us to an apartment 50 metres away, which was nice, but we didn't have all the hotel amenities directly although they were available for us (breakfast, pool etc) All in all it was good.
Reviewed on Sep 2, 2023

Hydrele Beach Hotel
Potokaki beach, Pythagorion Samos Samos island
$142 nightly
The price is $167 total per night from May 1 to May 2
$167 total
May 1 - May 2
Total with taxes and fees
A private beach and a restaurant are featured at this smoke-free hotel. Relax with sun loungers and beach umbrellas, and cool off with a drink at the beachside ...
Nice facilities. Very helpful and pleasant staff.
Reviewed on Sep 11, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Pythagorio hotels

Doryssa Seaside Resort
Pythagoreiou-Choras Samos Samos Island
$174 nightly
The price is $208 total per night from May 2 to May 3
$208 total
May 2 - May 3
Total with taxes and fees
8.6/10 Excellent! (153 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Pythagorio hotel reviews by fellow wanderers

Casa Cook Samos
5 out of 5
Posted 6 months ago
Travelocity Verified Review
"Clean and modernly decorated rooms with all the facilities"
A verified traveler stayed at Casa Cook Samos
Explore More Ways to Travel with Travelocity
- Hotels near Samos Pythagorion Archaeological Museum
- Mitilinii Hotels
- Ireon Hotels
- Vathi Hotels
- Limnionas Hotels
- 5 Star Hotels in Samos
- Farmstay in Samos
- B&B in Samos
- Extended Stay Hotels in Samos
- All Inclusive Resorts & in Samos
- Beach Resorts & in Samos
- Gay Friendly Hotels in Samos
- Golf Resorts & in Samos
- Pet Friendly Hotels in Samos
- Spa Resorts & in Samos
- Hotel Wedding Venues Hotels in Samos
- Winery Hotels in Samos
- Samos Hotels
- Houseboats in Samos
- Hotels near Profitis Ilias
- Drakei Hotels
- Hotels near Tsamadou Beach
- Paleokastro Hotels
- Marathokampos Hotels
- Hotels near Tsabou Beach
- Avlakia Hotels
- Flights from Samos Intl.
- Aegean Tel Aviv (TLV) to Samos (SMI) flights
- Aegean Düsseldorf (DUS) to Samos (SMI) flights
- Aegean Athens (ATH) to Samos (SMI) flights
- Aegean Rome (FCO) to Samos (SMI) flights
- Aegean London (LHR) to Samos (SMI) flights
- Aegean Larnaca (LCA) to Samos (SMI) flights
- Aegean Mytilene (MJT) to Samos (SMI) flights
- Aegean Belgrade (BEG) to Samos (SMI) flights
- Aegean Paris (CDG) to Samos (SMI) flights
- Aegean Zagreb (ZAG) to Samos (SMI) flights
- Aegean Zürich (ZRH) to Samos (SMI) flights
- Condor Frankfurt (FRA) to Samos (SMI) flights
- Condor Munich (MUC) to Samos (SMI) flights
- Hahn Air Athens (ATH) to Samos (SMI) flights
- Hahn Air Systems London (LHR) to Samos (SMI) flights
- Involatus Amsterdam (AMS) to Samos (SMI) flights
- Ita Airways Palermo (PMO) to Samos (SMI) flights
- Ita Airways Phoenix (PHX) to Samos (SMI) flights
- Lot-Polish Airlines Kraków (KRK) to Samos (SMI) flights
- Lufthansa Billund (BLL) to Samos (SMI) flights
- Lufthansa Bristol (BRS) to Samos (SMI) flights
- Lufthansa Düsseldorf (DUS) to Samos (SMI) flights
- Lufthansa Edinburgh (EDI) to Samos (SMI) flights
- Olympic Athens (ATH) to Samos (SMI) flights
- Sky express Rhodes (RHO) to Samos (SMI) flights
- Sky express Athens (ATH) to Samos (SMI) flights
- Sky express London (LHR) to Samos (SMI) flights
- Sky express Thessaloniki (SKG) to Samos (SMI) flights
- Sky express Mytilene (MJT) to Samos (SMI) flights
- Sky express Heraklion (HER) to Samos (SMI) flights
- Sky express Thira (JTR) to Samos (SMI) flights
- Swiss International Air Lines Cleveland (CLE) to Samos (SMI) flights
- Swiss International Air Lines London (LCY) to Samos (SMI) flights
- United Newark Liberty Intl. Airport (EWR) to Samos (SMI) flights
- United Tampa (TPA) to Samos (SMI) flights
- Flights from Atlanta (ATL) to Samos (SMI)
- Flights from Austin (AUS) to Samos (SMI)
- Flights from Bangor (BGR) to Samos (SMI)
- Flights from Birmingham (BHX) to Samos (SMI)
- Flights from Boston (BOS) to Samos (SMI)
- Flights from Detroit (DTW) to Samos (SMI)
- Flights from Indianapolis (IND) to Samos (SMI)
- Flights from New York (JFK) to Samos (SMI)
- Flights from Los Angeles (LAX) to Samos (SMI)
- Flights from London (LHR) to Samos (SMI)
- Flights from Madison (MSN) to Samos (SMI)
- Flights from Minneapolis (MSP) to Samos (SMI)
- Flights from Maastricht (MST) to Samos (SMI)
- Flights from Chicago (ORD) to Samos (SMI)
- Flights from Palermo (PMO) to Samos (SMI)
- Flights from Portland (PWM) to Samos (SMI)
- Flights from Raleigh (RDU) to Samos (SMI)
- Flights from Richmond (RIC) to Samos (SMI)
- Flights from Sofia (SOF) to Samos (SMI)
- Flights from Tel Aviv (TLV) to Samos (SMI)
- Flights from Tampa (TPA) to Samos (SMI)
- Flights from Sandefjord (TRF) to Samos (SMI)
- Flights from Moscow (VKO) to Samos (SMI)
- Flights to Samos






