Explore top 2026 5 Star Hotels in Samos

Name: Nirema Hotel & Spa Samos-Mgallery Collection
Price range: $404 total

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Top Samos 5 Star hotels

Casa Cook Samos

Potokaki, Pythagorion Samos

Fully refundableReserve now, pay when you stay

$380 nightly

$434 total

Aug 10 - Aug 11

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Enjoy beachfront dining and relax with free beach cabanas and sun loungers. ...

9.6/10 Exceptional! (107 reviews)

"Amazing property with beautiful amenities and excellent service. Maria in customer service was exceptional - helpful, informative and a pure delight to meet."

Reviewed on May 20, 2026

Doryssa Seaside Resort

Pythagoreiou-Choras Samos Samos Island

Fully refundableReserve now, pay when you stay

$285 nightly

$330 total

Aug 16 - Aug 17

Total with taxes and fees

A full-service spa, 2 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Enjoy beachfront dining and relax with sun loungers and beach ...

Proteas Blu Resort - Adults Only

Pythagorion Samos Samos Island

$148 nightly

$179 total

Aug 2 - Aug 3

Total with taxes and fees

This luxury hotel features a private beach, a full-service spa, and 3 restaurants. Relax with sun loungers and beach umbrellas, and cool off with a drink at ...

9.6/10 Exceptional! (101 reviews)

"It’s was very hilly but they had buggy’s to come and take you up and down the only downside was there was no tea and coffee making facilities in the room the food was first class had no problems getting sun beds in the morning both round the pool and at the beach"

Reviewed on Jun 28, 2026

Nirema Hotel & Spa Samos-Mgallery Collection

Malagari Samos

$354 nightly

$404 total

Aug 20 - Aug 21

Total with taxes and fees

A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Enjoy the gym and perks like free valet parking and a free beach ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Samos Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Samos to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Samos 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Samos before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Samos hotel reviews by fellow wanderers

Doryssa Theorem Hotel

5 out of 5

Posted 7 days ago

Travelocity Verified Review

"Nice and clean hotel in the heart of Pythagorio. Two minutes walk to beach, port, restaurants and famous cafe shops. No rental car needed is a big plus. Breakfast was looking good but we never had anything but a coffee. Bartender Iro was over and beyond with her service. If Samos is your destination and don’t want to move much, choose one of the doryssas from the chain (theorem or method if you would), you won’t regret it!"

A verified traveler stayed at Doryssa Theorem Hotel

Proteas Blu Resort - Adults Only

5 out of 5

Posted 3 weeks ago

Travelocity Verified Review

"It’s was very hilly but they had buggy’s to come and take you up and down the only downside was there was no tea and coffee making facilities in the room the food was first class had no problems getting sun beds in the morning both round the pool and at the beach"

A verified traveler stayed at Proteas Blu Resort - Adults Only

So Nice Hotel

5 out of 5

Posted 1 year ago

Travelocity Verified Review

"I'm a young lady travelling alone and was a bit nervous about finding the right place to stay in Samos, but So Nice Hotel exceeded my expectations! Here are some of the things I appreciated about my stay: -I had some questions and booking adjustments to make with them before I arrived, and their responses were quick and helpful. -They were kind enough a taxi to receive me at the airport which followed through even after a last-minute layover. -The room was clean and tidy with a small kitchen that made it possible to cook simple meals with ingredients from the market just a few minutes walk away. -The hotel is a small building operated by just a few people, all who were welcoming and kind. -The room had air conditioning! -Just down the road there are lots of shops and restaurants with beach access and sitting areas that are either complimentary or accessible for a small charge. (Tortuga was my favorite place right on the beach and Green Zone which is just across from the beach was my favorite place overall). -I felt totally safe and was confident that the So Nice staff would be willing to help me with any confusion or complications I may have. If I ever return to Samos, this place would be my first choice! "

A verified traveler stayed at So Nice Hotel