Book Hotels in Mayo, SC

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Top Mayo hotels

Four Points by Sheraton Spartanburg

Four Points by Sheraton Spartanburg

3 out of 5
9027 Fairforest Rd Spartanburg SC
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $132 total per night from Mar 15 to Mar 16
$132 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Staff was courteous. Room was clean.

Reviewed on Feb 25, 2026

Opens in a new windowFour Points by Sheraton Spartanburg
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

2.5 out of 5
895 Spartan Blvd Spartanburg SC
Fully refundable
$107 nightly
The price is $119 total per night from Mar 22 to Mar 23
$119 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
The stay was just fine with the exception that our room was right by the elevators and the noise was heard all night. Other than that, the stay was good. We will stay there again but will request to be away from the elevators.

Reviewed on Mar 2, 2026

Opens in a new windowHoliday Inn Express I-26 & Us 29 At Westgate Mall by IHG
Extended Stay America Premier Suites - Greenville - Spartanburg - I-85

Extended Stay America Premier Suites - Greenville - Spartanburg - I-85

2.5 out of 5
165 DEACON TILLER CT Duncan SC
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $100 total per night from Apr 3 to Apr 4
$100 total
Apr 3 - Apr 4
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free on-the-go breakfast each morning. Staff at the 24-hour ...
Clean

Reviewed on Feb 27, 2026

Opens in a new windowExtended Stay America Premier Suites - Greenville - Spartanburg - I-85
Spartanburg Marriott

Spartanburg Marriott

3.5 out of 5
299 North Church Street Spartanburg SC
$118 nightly
The price is $131 total per night from Mar 15 to Mar 16
$131 total
Mar 15 - Mar 16
Total with taxes and fees
This smoke-free hotel features 3 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free ...
The Barkeeper

Reviewed on Feb 27, 2026

Opens in a new windowSpartanburg Marriott
Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall

2.5 out of 5
458 West Blackstock Road Spartanburg SC
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $100 total per night from Mar 8 to Mar 9
$100 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
The room was ok per the pictures. Bed clean, room ok clean. If you don’t like carpet, don’t go there. It reeks of old, mildewed carpet. The ceiling had water damage and looked like it was going to collapse on us at any time. They charged me $123 because they said items were missing. 1 towel, 1 trashcan ...

Reviewed on Mar 3, 2026

Opens in a new windowComfort Suites At WestGate Mall
ECHO Suites Extended Stay by Wyndham Spartanburg

ECHO Suites Extended Stay by Wyndham Spartanburg

2 out of 5
490 W Blackstock Road Spartanburg SC
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $103 total per night from Mar 8 to Mar 9
$103 total
Mar 8 - Mar 9
Total with taxes and fees
A 24-hour gym, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Staff at the 24-hour front desk can provide ...
Have to pay for everything even towels more than every 14 days, to use TV, etc very disappointing

Reviewed on Feb 28, 2026

Opens in a new windowECHO Suites Extended Stay by Wyndham Spartanburg
Days Inn by Wyndham Spartanburg Waccamaw

Days Inn by Wyndham Spartanburg Waccamaw

2 out of 5
101 Outlet Rd Spartanburg SC
$57 nightly
The price is $63 total per night from Mar 13 to Mar 14
$63 total
Mar 13 - Mar 14
Total with taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this motel. Guests will appreciate free perks like on-the-go breakfast and ...
Yes

Reviewed on Mar 2, 2026

Opens in a new windowDays Inn by Wyndham Spartanburg Waccamaw
Sleep Inn Spartanburg Southwest

Sleep Inn Spartanburg Southwest

2.5 out of 5
501 South Blackstock Rd Spartanburg SC
Fully refundable
$62 nightly
The price is $69 total per night from Apr 1 to Apr 2
$69 total
Apr 1 - Apr 2
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Carpet was sticky and disgusting. Bed sheets and pillow cases dirty. Shower was outdated and disgusting. Water was terrible. Door was uneven so there was huge gaps. We only stayed for a few hours and just left.

Reviewed on Mar 2, 2026

Opens in a new windowSleep Inn Spartanburg Southwest
HomeTowne Studios by Red Roof Spartanburg - Asheville Highway

HomeTowne Studios by Red Roof Spartanburg - Asheville Highway

2 out of 5
130 Mobile Drive Spartanburg SC
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $60 total per night from Apr 1 to Apr 2
$60 total
Apr 1 - Apr 2
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Laundry facilities are provided for your convenience.
Heating doesn't work but they provided me with a fire place heater that works excellent air conditioning works great

Reviewed on Mar 4, 2026

Opens in a new windowHomeTowne Studios by Red Roof Spartanburg - Asheville Highway
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Mayo?
Great private home in convenient location is a great option for families on their way to Mayo. With useful amenities like a fireplace, this kid-friendly retreat makes guests of all ages feel at home.
Where can I find cheap hotels in Mayo?
At Travelocity you'll find really nice hotels in Mayo at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Mayo rather than in Mayo. We may find you even better rates, too.
How do I find the best Mayo hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Mayo then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Mayo?
The cheapest hotel in Mayo is $60. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Mayo?
There are 462 hotels in Mayo on Travelocity.
What are the best hotels in Mayo?
Mayo has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Mayo for you!
When is the best time to visit Mayo?
If you want the joy of a fun-filled trip in peak season, visit Mayo during March, April and October. If you'd prefer the peace of off-season, book a stay during quieter months, such as December, January and February.
When is the cheapest time to stay in Mayo?
Based on historic data is usually the cheapest month to visit Mayo. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Mayo?
There are multiple hotels in Mayo that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Mayo. We have plenty of kid-friendly hotels in Mayo to choose from on Travelocity!
Why book a hotel in Mayo through Travelocity?
Because we have the top hotels in Mayo! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Mayo on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Mayo hotel reviews by fellow wanderers

Tru by Hilton Spartanburg

Tru by Hilton Spartanburg

5 out of 5
Posted 13 hours ago
Travelocity Verified Review
"A quick in and out pit stop stay for my family on a routine long road trip we’ve had for take a few times. This is the second time we’ve stayed here. And it will be our go to stop. Clean, the breakfast is great. Friendly staff. "
A verified traveler stayed at Tru by Hilton Spartanburg
Tru by Hilton Spartanburg