Book Hotels in Mayo, SC

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Top Mayo hotels

Four Points by Sheraton Spartanburg

Four Points by Sheraton Spartanburg

3 out of 5
9027 Fairforest Rd Spartanburg SC
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $132 total per night from Jan 1 to Jan 2
$132 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
I enjoyed my stay at the hotel

Reviewed on Nov 29, 2025

Opens in a new windowFour Points by Sheraton Spartanburg
Tru by Hilton Spartanburg

Tru by Hilton Spartanburg

2.5 out of 5
103 Franklin Avenue Spartanburg SC
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $120 total per night from Jan 6 to Jan 7
$120 total
Jan 6 - Jan 7, 2026
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Bed was excellent!

Reviewed on Dec 19, 2025

Opens in a new windowTru by Hilton Spartanburg
Spartanburg Marriott

Spartanburg Marriott

3.5 out of 5
299 North Church Street Spartanburg SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $131 total per night from Dec 30 to Dec 31
$131 total
Dec 30 - Dec 31
Total with taxes and fees
This smoke-free hotel features 3 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free ...
Bed and pillows were amazing....

Reviewed on Dec 12, 2025

Opens in a new windowSpartanburg Marriott
Holiday Inn Express Gaffney by IHG

Holiday Inn Express Gaffney by IHG

2.5 out of 5
1031 HYATT STREET Gaffney SC
Fully refundable
$78 nightly
The price is $85 total per night from Dec 29 to Dec 30
$85 total
Dec 29 - Dec 30
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Staff was very professional and friendly

Reviewed on Dec 17, 2025

Opens in a new windowHoliday Inn Express Gaffney by IHG
Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall

2.5 out of 5
458 West Blackstock Road Spartanburg SC
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $99 total per night from Jan 4 to Jan 5
$99 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
The room was great.

Reviewed on Dec 18, 2025

Opens in a new windowComfort Suites At WestGate Mall
ECHO Suites Extended Stay by Wyndham Spartanburg

ECHO Suites Extended Stay by Wyndham Spartanburg

2 out of 5
490 W Blackstock Road Spartanburg SC
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $81 total per night from Dec 25 to Dec 26
$81 total
Dec 25 - Dec 26
Total with taxes and fees
A 24-hour gym, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Staff at the 24-hour front desk can provide ...
Yes

Reviewed on Dec 20, 2025

Opens in a new windowECHO Suites Extended Stay by Wyndham Spartanburg
Comfort Inn & Suites Spartanburg North

Comfort Inn & Suites Spartanburg North

2.5 out of 5
154 Candlenut Lane I-85 Exit 75 Spartanburg SC
$80 nightly
The price is $89 total per night from Dec 28 to Dec 29
$89 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Nice large room (king), wonderful bedding, clean room and bathroom, large TV. Had an enjoyable stay. Only negative was thin walls. But it didnt disturb our sleep.

Reviewed on Dec 18, 2025

Opens in a new windowComfort Inn & Suites Spartanburg North
Baymont by Wyndham Gaffney

Baymont by Wyndham Gaffney

2.5 out of 5
101 Stuard St Gaffney SC
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $66 total per night from Dec 24 to Dec 25
$66 total
Dec 24 - Dec 25
Total with taxes and fees
This motel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
The room was nice. The bed however was lumpy

Reviewed on Dec 14, 2025

Opens in a new windowBaymont by Wyndham Gaffney
Sleep Inn Spartanburg Southwest

Sleep Inn Spartanburg Southwest

2.5 out of 5
501 South Blackstock Rd Spartanburg SC
Fully refundable
$66 nightly
The price is $73 total per night from Dec 28 to Dec 29
$73 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
The.carpet in our room was wet by the bed. It took a long time for the water in the room to get hot, and the toilet seat was partially broken. The breakfast area was not maintained food wise and minimal selection. Thr area was not clean either.

Reviewed on Nov 29, 2025

Opens in a new windowSleep Inn Spartanburg Southwest
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Mayo?
Great private home in convenient location is a great option for families on their way to Mayo. With useful amenities like a fireplace, this kid-friendly retreat makes guests of all ages feel at home.
Where can I find cheap hotels in Mayo?
At Travelocity you'll find really nice hotels in Mayo at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Mayo rather than in Mayo. We may find you even better rates, too.
How do I find the best Mayo hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Mayo then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Mayo?
The cheapest hotel in Mayo is $66. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Mayo?
There are 440 hotels in Mayo on Travelocity.
What are the best hotels in Mayo?
Mayo has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Mayo for you!
When is the best time to visit Mayo?
If you want the joy of a fun-filled trip in peak season, visit Mayo during March, April and October. If you'd prefer the peace of off-season, book a stay during quieter months, such as December, January and February.
When is the cheapest time to stay in Mayo?
Based on historic data is usually the cheapest month to visit Mayo. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Mayo?
There are multiple hotels in Mayo that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Mayo. We have plenty of kid-friendly hotels in Mayo to choose from on Travelocity!
Why book a hotel in Mayo through Travelocity?
Because we have the top hotels in Mayo! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Mayo on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Mayo hotel reviews by fellow wanderers

AC Hotel by Marriott Spartanburg

AC Hotel by Marriott Spartanburg

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"The gentleman at the front desk when I checked in made me feel very comfortable. He was so chill. It was a great stay"
A verified traveler stayed at AC Hotel by Marriott Spartanburg
AC Hotel by Marriott Spartanburg