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Book a hotel near Mark Twain Boyhood Home and Museum, Hannibal
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Top hotels close to Mark Twain Boyhood Home and Museum
Best Western On The River
401 North 3rd Street Hannibal MO
Free Cancellation
Reserve now, pay when you stay
0.06 mi from Mark Twain Boyhood Home and Museum
$102 nightly
The price is $117 total per night
$117 total
Dec 30 - Dec 31
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the seasonal outdoor pool and free perks like self-serve breakfast and free self parking.
Pool
Hot Tub
Guest House with a River View, located downtown Hannibal, MO—- No Cleaning Fee
Hannibal MO
0.09 mi from Mark Twain Boyhood Home and Museum
This cottage features a water park and laundry facilities.
Kitchen
Washer
Riverside Inn Hannibal
111 Bird St Hannibal MO
Free Cancellation
Reserve now, pay when you stay
0.11 mi from Mark Twain Boyhood Home and Museum
$212 nightly
The price is $244 total per night
$244 total
Dec 30 - Dec 31
Total with taxes and fees
This guesthouse doesn't skimp on freebies - guests receive free WiFi and free self parking. A restaurant and express check-out are also provided.
Pool
Parking included
Garden House Bed and Breakfast
301 N 5th St Hannibal MO
Free Cancellation
Reserve now, pay when you stay
0.2 mi from Mark Twain Boyhood Home and Museum
$107 nightly
The price is $123 total per night
$123 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
Free WiFi in public areas is available at this bed & breakfast. Take advantage of the free self parking.
Parking included
Free WiFi
Happy Stay Inn
500 Mark Twain Ave Hannibal MO
0.28 mi from Mark Twain Boyhood Home and Museum
Free self parking is available and the hotel's front desk is staffed around-the-clock. Laundry facilities are provided for your convenience.
Pet friendly
Parking included
Gorgeous Victorian with Seasonal Pool , sleeps 8, pet friendly close to downtown
Hannibal MO
0.31 mi from Mark Twain Boyhood Home and Museum
$343 nightly
The price is $388 total per night
$388 total
Dec 30 - Dec 31
Total with taxes and fees
A water park and an outdoor pool are featured at this smoke-free vacation home. A garden, laundry facilities, and barbecue grills are also on offer.
Pool
Kitchen
The Indigo House- Located in the heart of Historic Hannibal, Missouri
Hannibal MO
0.35 mi from Mark Twain Boyhood Home and Museum
This vacation home featured laundry facilities and barbecue grills.
Kitchen
Washer
Lighthouse Inn & Suites
612 Mark Twain Ave Hannibal MO
Free Cancellation
Reserve now, pay when you stay
0.35 mi from Mark Twain Boyhood Home and Museum
$188 nightly
The price is $215 total per night
$215 total
Dec 30 - Dec 31
Total with taxes and fees
This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Dry cleaning is also provided.
Parking included
Free WiFi
Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
Hannibal MO
0.36 mi from Mark Twain Boyhood Home and Museum
$164 nightly
The price is $164 total per night
$164 total
Dec 30 - Dec 31
Total with taxes and fees
This vacation home includes a garden and laundry facilities.
Kitchen
Washer
The John Sydney House - Family and Pet Friendly Historic Home Downtown
Hannibal MO
0.49 mi from Mark Twain Boyhood Home and Museum
$207 nightly
The price is $227 total per night
$227 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
This vacation home features laundry facilities.
Kitchen
Washer
Motel 6 Hannibal, MO
123 Huckleberry Heights Dr Hannibal MO
Free Cancellation
Reserve now, pay when you stay
1.78 mi from Mark Twain Boyhood Home and Museum
$58 nightly
The price is $67 total per night
$67 total
Jan 14 - Jan 15, 2026
Total with taxes and fees
A restaurant, free self parking, and a 24-hour front desk are among this motel's amenities. WiFi in public areas is free. A snack bar/deli and a fireplace in the lobby are also provided.
Pet friendly
Parking included
Quality Inn & Suites Hannibal West
120 Lindsey Drive Hannibal MO
Free Cancellation
Reserve now, pay when you stay
3.97 mi from Mark Twain Boyhood Home and Museum
$70 nightly
The price is $81 total per night
$81 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free perks like buffet breakfast and free self parking.
Pool
Hot Tub
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See all available properties in Mark Twain Boyhood Home and Museum
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Mark Twain Boyhood Home and Museum hotels essential information
Accommodation | 182 hotels |
|---|---|
Lowest Price | $67 |
Highest Price | $388 |
Popular hotels | Lighthouse Inn & Suites, Best Western On The River, Quality Inn & Suites Hannibal West, Guest House with a River View, located downtown Hannibal, MO—- No Cleaning Fee, Riverside Inn Hannibal, Motel 6 Hannibal, MO, Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi, Happy Stay Inn, The John Sydney House - Family and Pet Friendly Historic Home Downtown, The Indigo House- Located in the heart of Historic Hannibal, Missouri , Garden House Bed and Breakfast, Gorgeous Victorian with Seasonal Pool , sleeps 8, pet friendly close to downtown |
Recent Mark Twain Boyhood Home and Museum hotel reviews by fellow wanderers
Quality Inn & Suites Hannibal West
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Great hotel !!!!"
A verified traveler stayed at Quality Inn & Suites Hannibal West
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