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Best Western San Isidro Inn

2.5 star property
Hotel near Laredo Regional Medical Center in Laredo

Choose dates to view prices

Photo gallery for Best Western San Isidro Inn

Lobby
Exterior
Premium bedding, in-room safe, iron/ironing board
Designer toiletries, hair dryer, towels
Meeting facility

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Pool
  • Parking included
  • Free WiFi
  • Air conditioning
  • Gym

Explore the area

View in a map
1410 Hospitality Drive, Laredo, TX, 78045
  • Place, Independence Plaza
    ‪12 min walk‬
  • Place, Duko's Dog Park
    ‪3 min drive‬
  • Place, Mall Del Norte
    ‪4 min drive‬
  • Airport, Laredo, TX (LRD-Laredo Intl.)
    ‪8 min drive‬

Room options

View all photos for Presidential Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave

Presidential Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave | Premium bedding, in-room safe, iron/ironing board

Presidential Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave

  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave

Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave | Premium bedding, in-room safe, iron/ironing board

Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave

  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave

Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave | Premium bedding, in-room safe, iron/ironing board

Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave

  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Standard Room, 1 King Bed, Accessible, Bathtub

Premium bedding, in-room safe, iron/ironing board

Standard Room, 1 King Bed, Accessible, Bathtub

9.0 out of 10
Wonderful
(4 reviews)
  • 320 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Standard Room, 1 King Bed, Accessible, Non Smoking

Premium bedding, in-room safe, iron/ironing board

Standard Room, 1 King Bed, Accessible, Non Smoking

7.0 out of 10
Good
(2 reviews)
  • 320 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Standard Room, 2 Queen Beds, Accessible, Bathtub

Premium bedding, in-room safe, iron/ironing board

Standard Room, 2 Queen Beds, Accessible, Bathtub

10.0 out of 10
Exceptional
(1 review)
  • 320 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Suite, 2 Queen Beds, Accessible, Bathtub

Premium bedding, in-room safe, iron/ironing board

Suite, 2 Queen Beds, Accessible, Bathtub

  • 320 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Standard Room, 2 Queen Beds, Accessible, Non Smoking

Premium bedding, in-room safe, iron/ironing board

Standard Room, 2 Queen Beds, Accessible, Non Smoking

10.0 out of 10
Exceptional
(1 review)
  • 320 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave

Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave | Premium bedding, in-room safe, iron/ironing board

Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave

9.0 out of 10
Wonderful
(11 reviews)
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave

Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave | Premium bedding, in-room safe, iron/ironing board

Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave

9.4 out of 10
Exceptional
(16 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 2 Queen Beds, Non Smoking, Refrigerator & Microwave

Premium bedding, in-room safe, iron/ironing board

Suite, 2 Queen Beds, Non Smoking, Refrigerator & Microwave

  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

1 King Bed, Non-Smoking, Executive Room, Microwave and Refrigerator, Desk, Recliner, Deluxe Bedding

  • Sleeps 2
  • Free WiFi

2 Queen Beds, Non-Smoking, Executive Room, Microwave and Refrigerator, Desk, Recliner, Deluxe Bedding

  • Sleeps 4
  • Free WiFi

1 King Bed, Non-Smoking, High Speed Internet Access, Microwave and Refrigerator, Deluxe Bedding, Recliner

  • Sleeps 2
  • Free WiFi

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About the neighborhood

Laredo

In Laredo .You'll find Laredo Regional Medical Center and Independence Plaza within 2 miles (3 km) of this hotel. Mall Del Norte and Texas A&M International University are also within 6 miles (10 km).

What's nearby

  • Independence Plaza - 12 min walk - 0.7 miles
  • Duko's Dog Park - 3 min drive - 1.2 miles
  • Mall Del Norte - 4 min drive - 4.7 miles
  • Texas A&M International University - 5 min drive - 5.7 miles
  • Sames Auto Arena - 7 min drive - 7.3 miles

Getting around

  • Laredo, TX (LRD-Laredo Intl.) - 12 min drive

Restaurants

  • ‪Chick-fil-A - ‬19 min walk
  • ‪Circle K - ‬14 min walk
  • McDonald's
  • ‪Cheddar's Scratch Kitchen - ‬3 min drive
  • Whataburger

About this property

Best Western San Isidro Inn

Hotel near Laredo Regional Medical Center in Laredo
Best Western San Isidro Inn offers its guests an outdoor pool and a 24-hour fitness center. WiFi is free in public spaces. A business center and a meeting room are available. Free breakfast is served. A vending machine, multilingual staff, and complimentary newspapers in the lobby are also featured at Best Western San Isidro Inn. Limited free parking is available on a first-come, first-served basis.

This Laredo hotel is smoke free.

  • 80 guestrooms or units
  • Full breakfast (free)
  • Poolside lounge chairs
  • Umbrellas for the pool
  • Business facilities
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Staff is multilingual
  • Front-desk safe
  • Convenience store
  • Newspapers in lobby (free)
  • ATM
  • Elevator
  • No smoking on site
  • 1 conference room
Best Western San Isidro Inn offers 80 air-conditioned accommodations with safes and coffee/tea makers. Beds feature premium bedding. 32-inch LED televisions come with premium cable channels. Guests can make use of the in-room refrigerators and microwaves. Bathrooms include designer toiletries, complimentary toiletries, and hair dryers.

This Laredo hotel provides complimentary wireless Internet access. Business-friendly amenities include phones along with free local calls (restrictions may apply). Housekeeping is provided daily.

Similar properties

Lobby
La Quinta Inn & Suites by Wyndham Laredo Airport
Laredo
  • Pool
  • Hot tub
  • Breakfast included
  • Free airport shuttle
4.6 out of 5, Wonderful, 1,004 reviews
$124 nightly
The price is $141
Jun 21 - Jun 22
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Laredo Airport

Property amenities

Family friendly

  • Fenced pool
  • Grocery/convenience store
  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • Laundry facilities
  • Outdoor pool
  • Rollaway/extra bed (surcharge)

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Free RV/bus/truck parking on site
  • Limited onsite self parking (max 10 spaces per unit)
  • Wheelchair-accessible parking available

Food and drink

  • Free full breakfast

Things to do

  • 24-hour gym
  • Outdoor pool

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Elevator
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool

Room amenities

Entertainment

  • 32-inch LED TV with premium cable channels
  • iPod dock

Bedroom

  • Free crib
  • Premium bedding
  • Rollaway/extra bed (surcharge)

Bathroom

  • Designer toiletries
  • Hair dryer
  • Private bathroom
  • Towels provided

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning
  • Connecting rooms available
  • Free local calls
  • Iron/ironing board
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: 3:00 AM
Late check-in subject to availability
Minimum check-in age: 18

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • No pets allowed, but service animals are welcome

Children and extra beds

  • Children are welcome.
  • Kids stay free! Up to 2 children 12 years old and younger stay free when using existing bedding.
  • Rollaway/extra beds are available for USD 10.0 per night.
  • Free cribs (infant beds)!

Property payment types

Important information

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Rollaway bed fee: USD 10.0 per night

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a carbon monoxide detector, a fire extinguisher, a smoke detector, a security system, and a first aid kit
This property has outdoor spaces, such as balconies, patios, terraces which may not be suitable for children; if you have concerns, we recommend contacting the property prior to your arrival to confirm they can accommodate you in a suitable room
This property affirms that it follows the cleaning and disinfection practices of We Care Clean (Best Western)
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. This property has outdoor spaces, such as balconies, patios, terraces which may not be suitable for children. If you have concerns, we recommend contacting the property prior to your arrival to confirm they can accommodate you in a suitable room. This property accepts Visa, Mastercard, American Express, and Discover. Cash is not accepted. For guests' safety, the property includes a carbon monoxide detector, a fire extinguisher, a smoke detector, a security system, and a first aid kit in each accommodation. Cashless payment methods are available for all transactions. This property affirms that it follows the cleaning and disinfection practices of We Care Clean (Best Western).

We should mention

  • Pool access available from 10:00 AM to 10:00 PM.
  • Up to 2 children 12 years old and younger stay free in the same room as the parent or guardian when using existing bedding.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Best Western San Isidro
Best Western San Isidro Inn
Best Western San Isidro Inn Laredo
Best Western San Isidro Laredo
San Isidro Inn
Best Western Laredo
Laredo Best Western
Best Western San Isidro Laredo
Best Western San Isidro Inn Hotel
Best Western San Isidro Inn Laredo
Best Western San Isidro Inn Hotel Laredo

Frequently asked questions

How close is Best Western San Isidro Inn to the airport?

Best Western San Isidro Inn is 7.2 mi (12-min drive) away from the Laredo, TX (LRD-Laredo Intl.) airport, the closest popular airport to the property.

How much does it cost to stay at Best Western San Isidro Inn?

As of Jun 6, 2026, prices found for a 1-night stay for 2 adults at Best Western San Isidro Inn on Jun 12, 2026 start from $154, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does Best Western San Isidro Inn have an airport shuttle?

Airport shuttle services are not available at Best Western San Isidro Inn.

Does Best Western San Isidro Inn offer free breakfast?

Yes, Best Western San Isidro Inn offers free breakfast.

Is there a casino at Best Western San Isidro Inn?

No, there is no casino at this hotel.

What time is check-in at Best Western San Isidro Inn?

Check-in start time: 3:00 PM; Check-in end time: 3:00 AM.

Is there free parking at Best Western San Isidro Inn?

This hotel offers free self parking.

Does Best Western San Isidro Inn have a pool?

Best Western San Isidro Inn features an outdoor pool. Guests can enjoy pool access from 10:00 AM to 10:00 PM.

Does Best Western San Isidro Inn have a spa?

There are no spa services available at this hotel.

How close is Best Western San Isidro Inn to downtown Laredo?

Best Western San Isidro Inn is 5.2 mi away from Laredo.

Best Western San Isidro Inn Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 250 out of 368 reviews
Rating 8 - Good. 72 out of 368 reviews
Rating 6 - Okay. 22 out of 368 reviews
Rating 4 - Poor. 13 out of 368 reviews
Rating 2 - Terrible. 11 out of 368 reviews

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.0/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

Javier

Great stay like always.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Cody Joe

Liked: Cleanliness, staff & service, property conditions & facilities
Very clean rooms, enjoyable pool, and great breakfast!
Stayed 3 nights in Sep 2025
Verified

10/10 Excellent

Carlos

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Easy access to major roadways; easy and convenient dining options
Stayed 2 nights in May 2025
Verified

10/10 Excellent

Julio

Liked: Property conditions & facilities
Todo excelente
Stayed 3 nights in Nov 2025
Verified

10/10 Excellent

Sergio

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice and clean hotel! Breakfast included and delicious…. The staff very nice
Stayed 2 nights in Aug 2025
Verified

10/10 Excellent

Roxann

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
My daughter and I truly enjoyed our stay here. Everything went very smooth, from checking in to checking out. I appreciated the courtesy call from front desk to remind of our checkout time. And, Juan was very friendly and assuring if we needed anything to reach out to him.☺️
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Melvin

Everything was like home. Excellent breakfast.
Stayed 1 night in Aug 2025
Verified

10/10 Excellent

Marcia

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The best stay in Laredo with most friendly staff. We love staying there and their breakfast is the best in town.
Stayed 2 nights in Oct 2023
Verified

10/10 Excellent

JIM

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great hotel in Laredo!

Our favorite place to stay in Laredo. Very convenient.
Stayed 1 night in Mar 2023
Verified

8/10 Good

Jose

Liked: Cleanliness, staff & service, property conditions & facilities
great location
Stayed 1 night in Jun 2023
Verified

10/10 Excellent

Ingrid

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent!! The staff really kind and nice!!
Stayed 3 nights in Aug 2025
Verified

8/10 Good

Johnny

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great stay. Good Motel.

Good stay
Stayed 3 nights in Aug 2022
Verified

10/10 Excellent

Andrew

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

A problem free stay with great breakfast.

The breakfast service was amazing and the front desk service was also.
Stayed 1 night in Dec 2022
Verified

10/10 Excellent

Adam

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This is my 3rd stay here & the service & cleanliness of the facility have been superior!
Stayed 1 night in May 2024
Verified

10/10 Excellent

Sandra

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Family visit

Our stay was great and it was clean. We had a good night quiet stay.
Stayed 1 night in Aug 2024
Verified

10/10 Excellent

Adrian

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Pleasant stay

I had no trouble checking in service was great room was clean and location was great.
Stayed 1 night in Oct 2024
Verified

10/10 Excellent

Johanna

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Would stay here again

The staff was very nice. Rooms have very nice, spacious, remodeled bathrooms. Very great value for a great room.
Stayed 1 night in Dec 2022
Verified

10/10 Excellent

Enrique

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Second time staying will always come again
Stayed 1 night in May 2025
Verified

10/10 Excellent

Marcia

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice staff and well maintained property. Very clean, too!
Stayed 2 nights in Feb 2023
Verified

8/10 Good

David

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Close to the areas we needed to be. Everything was clean and staff was nice.
Stayed 1 night in Jul 2023
Verified

10/10 Excellent

Alba

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Property is in a great area and very close to shops. Staff was amazing, courteous, and very helpful. Yummy homemade breakfast is a plus!!
Stayed 2 nights in Sep 2024
Verified

10/10 Excellent

Olivia

Liked: Cleanliness, staff & service, property conditions & facilities
The staff was helpful and very friendly. The breakfast was delicious! There are many places to dine and shop at.
Stayed 1 night in Jun 2023
Verified

10/10 Excellent

Gustavo

Liked: Staff & service, amenities, property conditions & facilities
Staff were very friendly and helpful. Property is quiet and felt very safe. Within 2-5 minute drive to many places to eat. I will definitely stay here again!
Stayed 2 nights in Oct 2022
Verified

8/10 Good

Rogelio

Liked: Cleanliness, staff & service
The hotel is dated/old but clean. need be i would stay here again.
Stayed 1 night in Apr 2023
Verified

8/10 Good

Monica

Liked: Cleanliness, staff & service
The staff were amazing. The room was decent but outdated, not much
Stayed 1 night in Apr 2025