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Top La Mesa hotels

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4 out of 5
Via Israel y Calle 71, San Francisco Panama City Panama
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $110 total per night from May 19 to May 20
$110 total
May 19 - May 20
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Excellent stay, close to urgent care offices

Reviewed on Apr 29, 2026

Opens in a new windowRamada Plaza by Wyndham Panama Punta Pacifica
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5 out of 5
Santa Maria Boulevard Panama City
Fully refundableReserve now, pay when you stay
$262 nightly
The price is $288 total per night from May 15 to May 16
$288 total
May 15 - May 16
Total with taxes and fees
This luxury hotel features a golf course, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Me gusta la.area el.hotell

Reviewed on Apr 29, 2026

Opens in a new windowThe Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Arcadia Condo Suites

Arcadia Condo Suites

2.5 out of 5
Calle rio mar Panama City Panamá Province
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $132 total per night from Apr 30 to May 1
$132 total
Apr 30 - May 1
Total with taxes and fees
This aparthotel features an outdoor pool and a rooftop terrace. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee shop ...
Absolutely wonderful

Reviewed on Apr 28, 2026

Opens in a new windowArcadia Condo Suites
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

4 out of 5
Avenida Domingo Diaz via Tocumen San Miguelito Panama
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $102 total per night from May 23 to May 24
$102 total
May 23 - May 24
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Only complaint is about we got the room facing busy streets it was really noisy all night long

Reviewed on Apr 25, 2026

Opens in a new windowCourtyard by Marriott Panama Metromall
Aloft Panama

Aloft Panama

3.5 out of 5
Via Israel & Calle 76 Panama City Panama
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $131 total per night from May 9 to May 10
$131 total
May 9 - May 10
Total with taxes and fees
A nightclub, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free ...
Exelente servicio y ubicación muy cómodo !!

Reviewed on Apr 26, 2026

Opens in a new windowAloft Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
$128 nightly
The price is $141 total per night from May 30 to May 31
$141 total
May 30 - May 31
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool, onsite laundry facilities, and babysitting. ...
El aire en el cuarto muy ruidosl de resto excelente

Reviewed on Apr 29, 2026

Opens in a new windowCrowne Plaza Panama Airport by IHG
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $148 total per night from May 8 to May 9
$148 total
May 8 - May 9
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor tennis courts are all featured at this smoke-free resort. Families will appreciate the playground, kid-friendly ...
Yes

Reviewed on Apr 24, 2026

Opens in a new windowSheraton Grand Panama
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Vía Tocumen Tocumen Panama
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $120 total per night from May 11 to May 12
$120 total
May 11 - May 12
Total with taxes and fees
This smoke-free resort features a casino, 2 indoor tennis courts, and a restaurant. Bring the family and enjoy the children's pool, playground, and kid-friendly ...
I went to the restaurant, looks clean and nice.. but the chicken l ordered wasn't cooked right... inside war raw. I was worried getting sick.. I didn't finish eating.. and they give me a discount. So I payed for a meal that I didn't enjoyed.

Reviewed on Apr 29, 2026

Opens in a new windowRiande Aeropuerto Hotel & Casino
Express Inn Panama International Airport Hostel

Express Inn Panama International Airport Hostel

1.5 out of 5
Calle Enrique Malek Tocumen
$50 nightly
The price is $54 total per night from Apr 30 to May 1
$54 total
Apr 30 - May 1
Total with taxes and fees
This hostel features a restaurant, an outdoor pool, and a bar/lounge. Guests will appreciate free perks like free self parking and WiFi in public areas. A terrace, ...
The property is literally falling apart. There is no electrical outlets, the chair by the small desk is ripped and the tv dangles in the wall. There is no channels. The windows have never been cleaned by looking at the amount of dirt on the inside. The bathroom is a mess, the toilet is loose both ...

Reviewed on Apr 26, 2026

Opens in a new windowExpress Inn Panama International Airport Hostel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in La Mesa?
Take some of the worries out of traveling with little ones by opting for a family-friendly hotel in La Mesa. From well-thought-out amenities to innovative services, these stays offer perks that'll help make your trip run smoothly: You're well catered for at The Jungle Lodge at Kalu Yala - Glamping. It comes with a swimming pool, childcare services and a flair for making families feel welcome. The Camp at Kalu Yala is another great choice. After an exciting day of exploring La Mesa, return to your cozy room and amenities like a swimming pool and a children's club.
Where can I find cheap hotels in La Mesa?
At Travelocity you'll find really nice hotels in La Mesa at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near La Mesa rather than in La Mesa. We may find you even better rates, too.
How do I find the best La Mesa hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in La Mesa then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in La Mesa?
The cheapest hotel in La Mesa is $54. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in La Mesa?
There are 393 hotels in La Mesa on Travelocity.
What are the best hotels in La Mesa?
La Mesa has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in La Mesa for you!
When is the best time to visit La Mesa?
If you want the joy of a fun-filled trip in peak season, visit La Mesa during February, March and May. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, July and December.
When is the cheapest time to stay in La Mesa?
Based on historic data is usually the cheapest month to visit La Mesa. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in La Mesa?
There are multiple hotels in La Mesa that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to La Mesa. We have plenty of kid-friendly hotels in La Mesa to choose from on Travelocity!
Why book a hotel in La Mesa through Travelocity?
Because we have the top hotels in La Mesa! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in La Mesa on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent La Mesa hotel reviews by fellow wanderers

ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport

4 out of 5
Posted 1 hour ago
Travelocity Verified Review
"It is a nice place. The staff was very helpful The picked me up at the airport and took me back, it's great"
A verified traveler stayed at ORHO HOTEL BOUTIQUE PANAMA Airport
ORHO HOTEL BOUTIQUE PANAMA Airport

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