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Top Isla Santay hotels

Holiday Inn Guayaquil Airport by IHG
Av. de Las Américas,junto al Aeropuerto Guayaquil Guayas
Fully refundable
$85 nightly
The price is $96 total per night from May 3 to May 4
$96 total
May 3 - May 4
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Clean room,nice staff
Reviewed on Apr 3, 2026

Oro Verde Guayaquil
9 De Octubre Y Garcia Moreno Guayaquil Guayas
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $96 total per night from Apr 5 to Apr 6
$96 total
Apr 5 - Apr 6
A full-service spa, 5 restaurants, and an outdoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free ...
It’s always a pleasure at the Oro Verde!
Reviewed on Mar 30, 2026

Wyndham Guayaquil Puerto Santa Ana
Calle Numa Pompilio Llona S N Guayaquil Guayas
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Apr 5 to Apr 6
$112 total
Apr 5 - Apr 6
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
The complimentary airport shuttle service was excellent and very helpful, especially for very late arrival flights. The shuttle driver would hold a sign with your name waiting for you. The breakfast was very good.
Reviewed on Apr 2, 2026

Unipark by Oro Verde Hotels
Clemente Ballén 406 Guayaquil Guayas
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $74 total per night from Apr 5 to Apr 6
$74 total
Apr 5 - Apr 6
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
Clean, very comfortable bed .Centrally located, near touristy places . I will stay again
Reviewed on Apr 1, 2026

Wyndham Garden Guayaquil
Juan Tanca Marengo Ave Guayaquil Guayas
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $84 total per night from Apr 5 to Apr 6
$84 total
Apr 5 - Apr 6
This Beaux Arts hotel includes 2 restaurants, a hot tub, and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Excellent choice of hotel. Easy access from airport, friendly staff and excellent breakfast.
Reviewed on Mar 20, 2026

Grand Hotel Guayaquil, an Ascend Collection Hotel
Boyaca 1615 Guayaquil Guayas
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $81 total per night from Apr 8 to Apr 9
$81 total
Apr 8 - Apr 9
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Bring the family and enjoy the children's pool, arcade/game room, and kid-friendly dining. ...
The breakfast was a fresh menu and selection
Reviewed on Mar 27, 2026

Sheraton Guayaquil Hotel
Av. Constitucion, Plaza del Sol Guayaquil Guayas
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Apr 5 to Apr 6
$102 total
Apr 5 - Apr 6
This hotel features 2 restaurants, 2 hot tubs, and an outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
My stay at the Sheraton Hotel was exceptional from start to finish. The moment I arrived, the staff made me feel genuinely welcomed with their friendly attitude and attentive service. The lobby and common areas were spotless, modern, and inviting—exactly the kind of atmosphere that sets the tone ...
Reviewed on Mar 15, 2026

TRYP by Wyndham Guayaquil Airport
Av. Joaquín Orrantia y L. Benitez Guayaquil Guayas
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $96 total per night from Apr 5 to Apr 6
$96 total
Apr 5 - Apr 6
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...
no cuartos limpios
Reviewed on Mar 30, 2026

Hilton Colon Guayaquil
Av Francisco de Orellana Mz 111 Guayaquil
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Apr 12 to Apr 13
$106 total
Apr 12 - Apr 13
A full-service spa, 5 restaurants, and an outdoor pool are all featured at this luxury hotel. Families will appreciate the playground, barbecue grills, and babysitting. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Isla Santay hotel reviews by fellow wanderers

Holiday Inn Guayaquil Airport by IHG
3 out of 5
Posted 1 day ago
Travelocity Verified Review
"Clean room,nice staff"
A verified traveler stayed at Holiday Inn Guayaquil Airport by IHG
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- Flights from Jose Joaquin de Olmedo Intl.
- Air Canada Toronto (YYZ) to Guayaquil (GYE) flights
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