Book Hotels in Isla Santay
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top Isla Santay hotels
Oro Verde Guayaquil
9 De Octubre Y Garcia Moreno Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is $96 total per night from Feb 16 to Feb 17
$96 total
per night
Feb 16 - Feb 17
A full-service spa, 5 restaurants, and an outdoor pool are all featured at this hotel. Traveling on business? Take advantage of the business center, free WiFi ...
Staff and clean rooms
Reviewed on Feb 9, 2026
Holiday Inn Guayaquil Airport by IHG
Av. de Las Américas,junto al Aeropuerto Guayaquil Guayas
Fully refundable
The price is $105 total per night from Feb 27 to Feb 28
$105 total
per night
Feb 27 - Feb 28
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
We arrived at 3am to our transfer waiting for us, the staff were all friendly and attentive. The room was spacious and clean, and the bed was very comfortable.
Reviewed on Feb 9, 2026
Wyndham Guayaquil Puerto Santa Ana
Calle Numa Pompilio Llona S N Guayaquil Guayas
The price is $107 total per night from Feb 17 to Feb 18
$107 total
per night
Feb 17 - Feb 18
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
Staff was very friendly, food spectacular, and the infrastructure was amazing! Spa was a plus...
Reviewed on Feb 5, 2026
Wyndham Garden Guayaquil
Juan Tanca Marengo Ave Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is $90 total per night from Feb 16 to Feb 17
$90 total
per night
Feb 16 - Feb 17
This Beaux Arts hotel includes 2 restaurants, a hot tub, and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Cold AC. Great customer service. You will find anything that you need within walking distance. Super clean room
Reviewed on Feb 7, 2026
Unipark by Oro Verde Hotels
Clemente Ballén 406 Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is $74 total per night from Feb 16 to Feb 17
$74 total
per night
Feb 16 - Feb 17
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
Every stay here is an amazing experience this is my third one, the hotel gave us an upgrade in our room, the view to the Cathedral and the Iguanas park was spectacular, the breakfast was great with a lot of variety of fruits, omelets, ceviches, bread and pastries my favorite was their oatmeal made ...
Reviewed on Feb 7, 2026
TRYP by Wyndham Guayaquil Airport
Av. Joaquín Orrantia y L. Benitez Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is $91 total per night from Feb 17 to Feb 18
$91 total
per night
Feb 17 - Feb 18
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...
What truly stood out was the overall experience. The breakfast was exceptional — varied every day, with a perfect balance between local Ecuadorian dishes and international options. The staff’s attention was outstanding, always warm and professional, and the room was spotless, comfortable, and very ...
Reviewed on Feb 3, 2026
Sheraton Guayaquil Hotel
Av. Constitucion, Plaza del Sol Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is $113 total per night from Feb 16 to Feb 17
$113 total
per night
Feb 16 - Feb 17
This hotel features 2 restaurants, 2 hot tubs, and an outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Room spotless and staff very friendly
Reviewed on Feb 5, 2026
Hilton Colon Guayaquil
Av Francisco de Orellana Mz 111 Guayaquil
Fully refundableReserve now, pay when you stay
The price is $106 total per night from Mar 1 to Mar 2
$106 total
per night
Mar 1 - Mar 2
A full-service spa, 5 restaurants, and an outdoor pool are all featured at this luxury hotel. Families will appreciate the playground, barbecue grills, and babysitting. ...
Did meet my expectation
Reviewed on Feb 7, 2026
Hotel Puerto Pacifico Guayaquil Airport
Av 33. Ciudadela La Garzota Guayaquil Guayas
Fully refundableReserve now, pay when you stay
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport ...
Clean, friendly staff, central..
Reviewed on Feb 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Isla Santay hotel reviews by fellow wanderers
Holiday Inn Guayaquil Airport by IHG
5 out of 5
Posted 6 days ago
Travelocity Verified Review
"We arrived at 3am to our transfer waiting for us, the staff were all friendly and attentive. The room was spacious and clean, and the bed was very comfortable. "
A verified traveler stayed at Holiday Inn Guayaquil Airport by IHG
Explore More Ways to Travel with Travelocity
- Tarifa Hotels
- Samborondon Hotels
- Hotels near Plaza del Monociclo
- Hotels near George Capwell Stadium
- Hotels with Airport Transfers in Simón Bolívar
- Simón Bolívar Hotels
- Chongón Hotels
- Tarqui Hotels
- Juan Montalvo Hotels
- Beach Resorts & in Urdesa
- Pascuales Hotels
- Guayacanes Hotels
- Guayaquil Hotels
- Sauce Hotels
- Barranco Hotels
- Delia Hotels
- La Aurora Hotels
- Hotels near Guayaquil Historic Park
- Hotels with Suites in Downtown Guayaquil
- Hotels with Room Service in Downtown Guayaquil
- Downtown Guayaquil Hotels
- Hotels near U.S. Consulate General
- Miraflores Hotels
- Daular Hotels
- Guayas Hotels
- Beach Resorts & in Ecuador
- Kid Friendly Hotels in Ecuador
- Hotels with Suites in Ecuador
- Hotels with Pools in Ecuador
- Luxury Hotels in Ecuador
- Spa Resorts & in Ecuador
- Ecuador Hotels
- Rosa Elvira Hotels
- San Jerónimo Hotels
- Guayaquil Hotels
- Boutique Hotels in Kennedy
- Convention Center Hotels in Kennedy
- Kennedy Hotels
- La Clementina Hotels
- Hotels near Jose Joaquin de Olmedo Intl.
- Luxury Hotels in Las Peñas
- Apartments in Duran
- Duran Hotels
- Inns in Duran
- Vacation Homes in Duran
- Casiguana Hotels
- Flights from Jose Joaquin de Olmedo Intl.
- Air Canada Toronto (YYZ) to Guayaquil (GYE) flights
- American Airlines Charlotte (CLT) to Guayaquil (GYE) flights
- American Airlines Dallas (DFW) to Guayaquil (GYE) flights
- American Airlines Boston (BOS) to Guayaquil (GYE) flights
- American Airlines Miami (MIA) to Guayaquil (GYE) flights
- American Airlines Nashville (BNA) to Guayaquil (GYE) flights
- American Airlines Chicago (ORD) to Guayaquil (GYE) flights
- American Airlines Philadelphia (PHL) to Guayaquil (GYE) flights
- American Airlines Seattle (SEA) to Guayaquil (GYE) flights
- Avianca Bogotá (BOG) to Guayaquil (GYE) flights
- Avianca New York (JFK) to Guayaquil (GYE) flights
- Avianca Los Angeles (LAX) to Guayaquil (GYE) flights
- Avianca Quito (UIO) to Guayaquil (GYE) flights
- Copa Mexico City (MEX) to Guayaquil (GYE) flights
- Copa Newark Liberty Intl. Airport (EWR) to Guayaquil (GYE) flights
- Copa Chicago (ORD) to Guayaquil (GYE) flights
- Copa Orlando (MCO) to Guayaquil (GYE) flights
- Copa Tampa (TPA) to Guayaquil (GYE) flights
- Copa Panama City (PTY) to Guayaquil (GYE) flights
- Copa Washington (IAD) to Guayaquil (GYE) flights
- Delta Atlanta (ATL) to Guayaquil (GYE) flights
- Delta New York (JFK) to Guayaquil (GYE) flights
- Delta Minneapolis (MSP) to Guayaquil (GYE) flights
- Delta Raleigh (RDU) to Guayaquil (GYE) flights
- Eastern Airlines New York (JFK) to Guayaquil (GYE) flights
- Jetblue Airways Fort Lauderdale (FLL) to Guayaquil (GYE) flights
- Jetblue Airways New York (JFK) to Guayaquil (GYE) flights
- Jetblue Airways Miami (MIA) to Guayaquil (GYE) flights
- Jetblue Airways Newark Liberty Intl. Airport (EWR) to Guayaquil (GYE) flights
- Latam Airlines Group New York (JFK) to Guayaquil (GYE) flights
- Latam Airlines Group Miami (MIA) to Guayaquil (GYE) flights
- Spirit Airlines Fort Lauderdale (FLL) to Guayaquil (GYE) flights
- Flights from Baltimore (BWI) to Guayaquil (GYE)
- Flights from Charlotte (CLT) to Guayaquil (GYE)
- Flights from Cuenca (CUE) to Guayaquil (GYE)
- Flights from Washington (IAD) to Guayaquil (GYE)
- Flights from New York (JFK) to Guayaquil (GYE)
- Flights from New York (LGA) to Guayaquil (GYE)
- Flights from Orlando (MCO) to Guayaquil (GYE)
- Flights from Miami (MIA) to Guayaquil (GYE)
- Flights from Chicago (ORD) to Guayaquil (GYE)
- Flights from Raleigh (RDU) to Guayaquil (GYE)
- Flights from San Francisco (SFO) to Guayaquil (GYE)
- Flights from Salt Lake City (SLC) to Guayaquil (GYE)
- Flights from Quito (UIO) to Guayaquil (GYE)
- Flights to Duran
