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Comfort Inn & Suites Santee

2.5 star property
Santee guestrooms with comfy beds

Choose dates to view prices

Photo gallery for Comfort Inn & Suites Santee

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes
A modern living room with teal and orange chairs, a grey sofa, a fireplace, and a staircase.
A modern living room with a sofa, a red ottoman, a TV mounted on the wall, and a wooden entertainment unit.
A spacious lobby with a modern staircase, seating area with orange and teal chairs, and a fireplace.
A room with a black console table displaying coffee and tea options, a large window, and a sliding glass door leading to a dining area with red chairs.

Reviews

8.0 out of 10
Very good

Popular amenities

  • Pool
  • Parking included
  • Free WiFi
  • Air conditioning
  • Gym

Explore the area

View in a map
221 Britain St, Santee, SC, 29142
  • Place, Santee Cooper Country Club
    ‪13 min walk‬
  • Place, Santee State Park
    ‪16 min walk‬
  • Place, Santee National Golf Club
    ‪1 min drive‬

Room options

View all photos for Standard Room, 1 King Bed

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Standard Room, 1 King Bed

9.2 out of 10
Wonderful
(25 reviews)
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Standard Room, 2 Queen Beds

A hotel room with two beds, a TV, a desk with a lamp, and a mirror.

Standard Room, 2 Queen Beds

7.8 out of 10
Good
(35 reviews)
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Suite, Non Smoking

A hotel room with two single beds, a desk with a chair, a round mirror, and a flat-screen TV mounted on the wall.

Suite, Non Smoking

7.6 out of 10
Good
(27 reviews)
  • Sleeps 6
  • 2 Queen Beds and 1 Double Sofa Bed
  • Free WiFi

View all photos for Room, 1 King Bed, Accessible, Non Smoking

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Room, 1 King Bed, Accessible, Non Smoking

8.6 out of 10
Excellent
(8 reviews)
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Room, 2 Queen Beds, Accessible, Non Smoking

A hotel room with two beds, a TV, a desk with a lamp, and a mirror.

Room, 2 Queen Beds, Accessible, Non Smoking

9.0 out of 10
Wonderful
(9 reviews)
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Suite, 1 King Bed, Accessible, Non Smoking

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Suite, 1 King Bed, Accessible, Non Smoking

10.0 out of 10
Exceptional
(1 review)
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Suite, Multiple Beds, Accessible, Non Smoking

A hotel room with two single beds, a desk with a chair, a round mirror, and a flat-screen TV mounted on the wall.

Suite, Multiple Beds, Accessible, Non Smoking

7.6 out of 10
Good
(9 reviews)
  • Sleeps 6
  • 2 Queen Beds and 1 Double Sofa Bed
  • Free WiFi

View all photos for Standard Room, 1 King Bed

A bathroom with a sink, mirror, toilet, and framed pictures on the wall.

Standard Room, 1 King Bed

  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Standard Room, 2 Queen Beds

A hotel room with two beds, a desk with a TV, a chair, a desk lamp, and a window with curtains.

Standard Room, 2 Queen Beds

  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Room, 1 King Bed, Accessible, Non Smoking

A hotel room with a large bed, two bedside tables, a chair, a desk, and a window with curtains.

Room, 1 King Bed, Accessible, Non Smoking

  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall)

A modern living room with a sofa, a red ottoman, a TV mounted on the wall, and a wooden entertainment unit.

Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall)

  • Sleeps 4
  • 1 Queen Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall)

A hotel room with a large bed, a nightstand, a wall-mounted lamp, and a framed picture on the wall.

Suite, 1 King Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall)

  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking (1 Room Suite, No Smkng/Interior Hall)

A hotel room with a large bed, a nightstand, a wall-mounted lamp, and a framed picture on the wall.

Suite, 1 King Bed with Sofa bed, Non Smoking (1 Room Suite, No Smkng/Interior Hall)

  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

About the neighborhood

Santee

In entertainment district.You'll find Lake Marion and Santee Cooper Country Club within a 15-minute walk of this Santee hotel. Santee National Golf Club and Santee Town Hall are also within 2 miles (3 km).

What's nearby

  • Santee Cooper Country Club - 13 min walk - 0.7 miles
  • Santee State Park - 16 min walk - 0.9 miles
  • Santee National Golf Club - 1 min drive - 1.3 miles
  • Santee Town Hall - 2 min drive - 1.3 miles
  • South Carolina State University - 27 min drive - 29.0 miles

Getting around

  • Charleston Intl. Airport (CHS) - 58 min drive

Restaurants

  • ‪McDonald's - ‬4 min walk
  • ‪Starbucks - ‬9 min walk
  • ‪Cork And Barrel - ‬6 min walk
  • ‪Armando’s Mexican Restaurant - ‬18 min walk
  • ‪Cracker Barrel - ‬5 min walk

About this property

Comfort Inn & Suites Santee

Santee guestrooms with comfy beds
Comfort Inn & Suites Santee offers its guests a fitness center and a seasonal outdoor pool. A computer station is on site and WiFi is free in public spaces. There's an onsite business center. Free breakfast is served. A vending machine, multilingual staff, and coffee/tea in a common area are also featured at Comfort Inn & Suites Santee. Limited free parking is available on a first-come, first-served basis. A complete renovation of Comfort Inn & Suites Santee was completed in December 2023.

Smoking is allowed in designated areas at this Santee hotel.

  • 1 building
  • 61 guestrooms or units
  • 3 levels
  • Buffet breakfast (free)
  • Business facilities
  • Coffee in lobby
  • Self-service laundry
  • Front desk (24 hours)
  • Staff is multilingual
  • Front-desk safe
  • Newspapers in lobby (free)
  • Fireplace in lobby
  • Television in lobby
  • Elevator
  • Smoking in designated areas
  • Water dispenser
Comfort Inn & Suites Santee offers 61 accommodations with coffee/tea makers and hair dryers. Pillowtop beds feature Frette Italian sheets and premium bedding. Plasma televisions come with satellite channels. Bathrooms include shower/tub combinations.

Guests can surf the web using the complimentary wireless Internet access. Business-friendly amenities include phones along with free local calls (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is provided daily.

Similar properties

Exterior
Best Western Plus Santee Inn
Santee
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
4.4 out of 5, Excellent, 1,010 reviews
$117 nightly
The price is $130
Jul 28 - Jul 29
Total with taxes and fees
Best Western Plus Santee Inn

Property amenities

Family friendly

  • In-room crib
  • In-room microwave
  • Laundry facilities
  • Seasonal outdoor pool

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Limited onsite self parking
  • Wheelchair-accessible parking available

Food and drink

  • Free buffet breakfast
  • Coffee and tea in common areas

Things to do

  • Gym
  • Seasonal outdoor pool
  • TV in common areas

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • 4 accessible parking spaces
  • Assistive listening devices
  • Braille/raised signage
  • Elevator
  • Front entrance ramp
  • Lever door handles
  • Pool hoist on site
  • Visual alarms in hallways
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom

Room amenities

Entertainment

  • Plasma TV with satellite channels

Bedroom

  • Blackout drapes
  • Free crib
  • Frette Italian sheets
  • Pillowtop mattress

Bathroom

  • Hair dryer
  • Private bathroom
  • Shower/bathtub combination
  • Towels provided

Food and drink

  • Coffee/tea maker
  • Microwave

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Free local calls
  • Heating (climate-controlled)
  • Iron/ironing board
  • Phone

Policies

Check-in

Check-in time starts at 3:00 PM

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property
The credit card used to book the reservation must be presented by the cardholder at check-in along with matching photo identification, and other arrangements must be coordinated with the property prior to arrival
Information provided by the property may be translated using automated translation tools

Renovations and closures

The following facilities or services will be unavailable from June 23 2026 to July 18 2026 (dates subject to change):
  • Fitness facilities

Access methods

Staffed front desk

Pets

  • No pets allowed, but service animals are welcome

Children and extra beds

  • Children are welcome.
  • Kids stay free! Children 15 years old and younger stay free when using existing bedding.
  • Rollaway/extra beds are not available.
  • Free cribs (infant beds)!

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
This property reserves the right to pre-authorize the guest's credit card prior to arrival.
Only bookings from non-local guests are accepted; guests whose residence is within 45 mi (72 km) of the property will not be allowed to check in
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice)
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation. This property accepts Visa, Mastercard, American Express, and Discover. Cash is not accepted. This property reserves the right to pre-authorize the guest's credit card prior to arrival. Only bookings from non-local guests are accepted. Guests whose residence is within 45 mi (72 km) of the property will not be allowed to check in.
    This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice).

We should mention

  • The seasonal pool will open in March and close in October.
  • Pool access available from 10 AM to 10 PM.
  • Children 15 years old and younger stay free in the same room as the parent or guardian when using existing bedding.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.

Property is also known as

Comfort Inn Hotel Santee
Comfort Inn Santee
Comfort Inn Santee Hotel
Comfort Inn Suites Santee
Comfort & Suites Santee Santee
Comfort Inn & Suites Santee Hotel
Comfort Inn & Suites Santee Santee

Frequently asked questions

How close is Comfort Inn & Suites Santee to the airport?

Comfort Inn & Suites Santee is 60.2 mi (58-min drive) away from the Charleston Intl. Airport (CHS) airport, the closest popular airport to the property.

How much does it cost to stay at Comfort Inn & Suites Santee?

As of Jul 21, 2026, prices found for a 1-night stay for 2 adults at Comfort Inn & Suites Santee on Aug 16, 2026 start from $108, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does Comfort Inn & Suites Santee have an airport shuttle?

Airport shuttle services are not available at Comfort Inn & Suites Santee.

Does Comfort Inn & Suites Santee offer free breakfast?

Yes, Comfort Inn & Suites Santee offers free breakfast.

Is there a casino at Comfort Inn & Suites Santee?

No, there is no casino at this hotel.

What time is check-in at Comfort Inn & Suites Santee?

Check-in begins at 3:00 PM.

Is there free parking at Comfort Inn & Suites Santee?

This hotel offers free self parking.

Does Comfort Inn & Suites Santee have a pool?

Comfort Inn & Suites Santee features a seasonal outdoor pool. Guests can enjoy pool access from 10 AM to 10 PM.

Does Comfort Inn & Suites Santee have a spa?

There are no spa services available at this hotel.

How close is Comfort Inn & Suites Santee to downtown Santee?

Comfort Inn & Suites Santee is 0.2 mi away from Santee.

Comfort Inn & Suites Santee Reviews

Reviews

8.0

Very Good

Rating 10 - Excellent. 437 out of 1005 reviews
Rating 8 - Good. 301 out of 1005 reviews
Rating 6 - Okay. 141 out of 1005 reviews
Rating 4 - Poor. 74 out of 1005 reviews
Rating 2 - Terrible. 52 out of 1005 reviews

8.2/10

Cleanliness

8.8/10

Staff & service

7.6/10

Amenities

7.8/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

Susan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Really nice breakfast.
Stayed 1 night in Apr 2026
Verified

10/10 Excellent

Fanny

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great staff.
Stayed 1 night in Apr 2026
Verified

10/10 Excellent

Kathleen

Liked: Cleanliness, staff & service
Room was spacious ans breakfast was good.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Ellis

Liked: Cleanliness, staff & service, amenities
Place was nice and will stay there again.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Joseph

Liked: Cleanliness, amenities, property conditions & facilities
Staff was friendly, room was clean, pleasant stay.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Dorothy

Liked: Cleanliness, staff & service
Great experience
Stayed 1 night in Mar 2026
Verified

8/10 Good

Mary

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean and basic, staff friendly, breakfast was a full buffet. Only downside was the noise from above and road noise from the nearby interstate.
Stayed 1 night in Apr 2026
Verified

10/10 Excellent

Deborah

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel was a little dated but clean.
Stayed 1 night in Feb 2026
Verified

8/10 Good

Dale

Liked: Cleanliness, amenities, property conditions & facilities
Clean rooms, nice staff, decent breakfast
Stayed 1 night in Jan 2026
Verified

8/10 Good

Salvador

Liked: Cleanliness, amenities, property conditions & facilities
Everything was perfect for a one night stay
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Kristi

Liked: Cleanliness, staff & service, amenities
Staff was very friendly and the room was large and very clean.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Margarita

Liked: Cleanliness, staff & service, amenities
Overall nice room, friendly staff, and great breakfast. Very satisfied with my stay.
Stayed 1 night in Dec 2025
Verified

8/10 Good

Shankar

Liked: Cleanliness, staff & service, property conditions & facilities
It was quite and comfortable stay
Stayed 1 night in Dec 2025
Verified

8/10 Good

Juan

Liked: Cleanliness, staff & service, amenities
Room was clean and bed was comfortable
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Tammi

Liked: Cleanliness, amenities, property conditions & facilities
The staff was excellent and the room was very clean. I would go there again.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Marilyn

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Yes, the gym was well equiped.
Stayed 1 night in Apr 2026
Verified

8/10 Good

Shawn

Liked: Cleanliness, staff & service, amenities
Very kind staff and comfortable room
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

gail

Liked: Cleanliness, staff & service, property conditions & facilities
Clean comfortable room
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Mark

Liked: Cleanliness, amenities, property conditions & facilities
Staff was pleasant and helpful with restaurant information, room clean.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Debra

Liked: Cleanliness, staff & service, amenities
The room was clean and comfortable. Night time check in clerk friendly and fast.
Stayed 1 night in Feb 2026
Verified

8/10 Good

Benoit

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room
Stayed 1 night in Apr 2026
Verified

10/10 Excellent

Michelle

Great place to stay.
Stayed 1 night in Jun 2025
Verified

6/10 Okay

moreen

Liked: Cleanliness, amenities, property conditions & facilities
Didn’t have breakfast. Parking was good. Well lit.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Laraine D

Liked: Cleanliness, amenities, property conditions & facilities
Check-in staff courteous and efficient. Clean, basic, comfortable room for a one night travel stay at good price. Good breakfast.
Stayed 1 night in Jan 2026
Verified

8/10 Good

Dorothy

Liked: Cleanliness, staff & service, amenities
Clean and comfortable. Staff very courteous!
Stayed 1 night in Jan 2026