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Comfort Inn & Suites Santee

2.5 star property
Santee guestrooms with comfy beds

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Photo gallery for Comfort Inn & Suites Santee

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes
Lobby
Free buffet breakfast
Lobby
Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall) | Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Reviews

8.0 out of 10
Very good

Popular amenities

  • Pool
  • Parking included
  • Free WiFi
  • Air conditioning
  • Gym

Explore the area

View in a map
221 Britain St, Santee, SC, 29142
  • Place, Santee Cooper Country Club
    ‪13 min walk‬
  • Place, Santee State Park
    ‪16 min walk‬
  • Place, Santee National Golf Club
    ‪2 min drive‬

Room options

View all photos for Standard Room, 1 King Bed

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Standard Room, 1 King Bed

9.2 out of 10
Wonderful
(24 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room, 2 Queen Beds

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Standard Room, 2 Queen Beds

7.8 out of 10
Good
(32 reviews)
  • Sleeps 4
  • 2 Queen Beds

View all photos for Suite, Non Smoking

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Suite, Non Smoking

8.0 out of 10
Very good
(24 reviews)
  • Sleeps 6
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Room, 1 King Bed, Accessible, Non Smoking

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Room, 1 King Bed, Accessible, Non Smoking

8.6 out of 10
Excellent
(8 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 2 Queen Beds, Accessible, Non Smoking

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Room, 2 Queen Beds, Accessible, Non Smoking

9.0 out of 10
Wonderful
(9 reviews)
  • Sleeps 4
  • 2 Queen Beds

View all photos for Suite, 1 King Bed, Accessible, Non Smoking

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Suite, 1 King Bed, Accessible, Non Smoking

10.0 out of 10
Exceptional
(1 review)
  • Sleeps 4
  • 1 King Bed

View all photos for Suite, Multiple Beds, Accessible, Non Smoking

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Suite, Multiple Beds, Accessible, Non Smoking

9.2 out of 10
Wonderful
(5 reviews)
  • Sleeps 6
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall)

Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall) | Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall)

  • Sleeps 4
  • 1 Queen Bed and 1 Double Sofa Bed

View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall)

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Suite, 1 King Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall)

  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking (1 Room Suite, No Smkng/Interior Hall)

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Suite, 1 King Bed with Sofa bed, Non Smoking (1 Room Suite, No Smkng/Interior Hall)

  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed

About the neighborhood

Santee

In entertainment district.You'll find Santee Cooper Country Club and Santee National Golf Club within 2 miles (3 km) of this hotel. Santee Town Hall and Santee State Park are also within 2 miles (3 km).

What's nearby

  • Santee Cooper Country Club - 13 min walk - 0.7 miles
  • Santee State Park - 16 min walk - 0.9 miles
  • Santee National Golf Club - 2 min drive - 1.3 miles
  • Lake Marion - 2 min drive - 2.3 miles
  • Santee Town Hall - 2 min drive - 1.3 miles

Getting around

  • Charleston Intl. Airport (CHS) - 58 min drive

Restaurants

  • ‪McDonald's - ‬4 min walk
  • ‪Starbucks - ‬9 min walk
  • ‪Elloree Truckstop & Diner - ‬11 min drive
  • ‪Enmarket - ‬4 min walk
  • ‪Cracker Barrel - ‬5 min walk

About this property

Comfort Inn & Suites Santee

Santee guestrooms with comfy beds
Comfort Inn & Suites Santee offers its guests a fitness center and a seasonal outdoor pool. A computer station is on site and WiFi is free in public spaces. There's an onsite business center. Free breakfast is served. A vending machine, multilingual staff, and coffee/tea in a common area are also featured at Comfort Inn & Suites Santee. Limited free parking is available on a first-come, first-served basis. A complete renovation of Comfort Inn & Suites Santee was completed in December 2023.

Smoking is allowed in designated areas at this Santee hotel.

  • 1 building
  • 61 guestrooms or units
  • 3 levels
  • Buffet breakfast (free)
  • Business facilities
  • Coffee in lobby
  • Self-service laundry
  • Front desk (24 hours)
  • Staff is multilingual
  • Front-desk safe
  • Newspapers in lobby (free)
  • Fireplace in lobby
  • Television in lobby
  • Elevator
  • Smoking in designated areas
  • Water dispenser
Comfort Inn & Suites Santee offers 61 accommodations with coffee/tea makers and hair dryers. Pillowtop beds feature Frette Italian sheets and premium bedding. Plasma televisions come with satellite channels. Bathrooms include shower/tub combinations.

Guests can surf the web using the complimentary wireless Internet access. Business-friendly amenities include phones along with free local calls (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is provided daily.

Similar properties

Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
4.0 out of 5, Very Good, 1,431 reviews
$80 nightly
The price is $89
Apr 2 - Apr 3
Total with taxes and fees
Baymont by Wyndham Santee

Property amenities

Family friendly

  • In-room crib
  • Laundry facilities
  • Seasonal outdoor pool

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Limited onsite self parking
  • Wheelchair-accessible parking available

Food and drink

  • Free buffet breakfast
  • Coffee and tea in common areas

Things to do

  • Gym
  • Seasonal outdoor pool
  • TV in common areas

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • 4 accessible parking spaces
  • Assistive listening devices
  • Braille/raised signage
  • Elevator
  • Front entrance ramp
  • Lever door handles
  • Pool hoist on site
  • Visual alarms in hallways
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom

Room amenities

Entertainment

  • Plasma TV with satellite channels

Bedroom

  • Blackout drapes
  • Free crib
  • Frette Italian sheets
  • Pillowtop mattress

Bathroom

  • Hair dryer
  • Private bathroom
  • Shower/bathtub combination
  • Towels provided

Food and drink

  • Coffee/tea maker

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Free local calls
  • Heating (climate-controlled)
  • Iron/ironing board
  • Phone

Policies

Check-in

Check-in time starts at 3:00 PM

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property
The credit card used to book the reservation must be presented by the cardholder at check-in along with matching photo identification, and other arrangements must be coordinated with the property prior to arrival
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • No pets allowed, but service animals are welcome

Children and extra beds

  • Children are welcome.
  • Kids stay free! Children 15 years old and younger stay free when using existing bedding.
  • Rollaway/extra beds are not available.
  • Free cribs (infant beds)!

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
This property reserves the right to pre-authorize the guest's credit card prior to arrival.
Only bookings from non-local guests are accepted; guests whose residence is within 45 mi (72 km) of the property will not be allowed to check in
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice)
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation. This property accepts Visa, Mastercard, American Express, and Discover. Cash is not accepted. This property reserves the right to pre-authorize the guest's credit card prior to arrival. Only bookings from non-local guests are accepted. Guests whose residence is within 45 mi (72 km) of the property will not be allowed to check in.
    This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice).

We should mention

  • The seasonal pool will open in March and close in October.
  • Pool access available from 10 AM to 10 PM.
  • Children 15 years old and younger stay free in the same room as the parent or guardian when using existing bedding.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.

Property is also known as

Comfort Inn Hotel Santee
Comfort Inn Santee
Comfort Inn Santee Hotel
Comfort Inn Suites Santee
Comfort & Suites Santee Santee
Comfort Inn & Suites Santee Hotel
Comfort Inn & Suites Santee Santee

Frequently asked questions

How close is Comfort Inn & Suites Santee to the airport?

Comfort Inn & Suites Santee is 60.2 mi (58-min drive) away from the Charleston Intl. Airport (CHS) airport, the closest popular airport to the property.

How much does it cost to stay at Comfort Inn & Suites Santee?

As of Apr 1, 2026, prices found for a 1-night stay for 2 adults at Comfort Inn & Suites Santee on Apr 26, 2026 start from $132, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does Comfort Inn & Suites Santee have an airport shuttle?

Airport shuttle services are not available at Comfort Inn & Suites Santee.

Does Comfort Inn & Suites Santee offer free breakfast?

Yes, Comfort Inn & Suites Santee offers free breakfast.

Is there a casino at Comfort Inn & Suites Santee?

No, there is no casino at this hotel.

What time is check-in at Comfort Inn & Suites Santee?

Check-in begins at 3:00 PM.

Is there free parking at Comfort Inn & Suites Santee?

This hotel offers free self parking.

Does Comfort Inn & Suites Santee have a pool?

Comfort Inn & Suites Santee features a seasonal outdoor pool. Guests can enjoy pool access from 10 AM to 10 PM.

Does Comfort Inn & Suites Santee have a spa?

There are no spa services available at this hotel.

How close is Comfort Inn & Suites Santee to downtown Santee?

Comfort Inn & Suites Santee is 0.2 mi away from Santee.

Comfort Inn & Suites Santee Reviews

Reviews

8.0

Very Good

Rating 10 - Excellent. 425 out of 1003 reviews
Rating 8 - Good. 299 out of 1003 reviews
Rating 6 - Okay. 145 out of 1003 reviews
Rating 4 - Poor. 81 out of 1003 reviews
Rating 2 - Terrible. 53 out of 1003 reviews

8.0/10

Cleanliness

8.6/10

Staff & service

7.6/10

Amenities

7.8/10

Property conditions & facilities

Reviews

2/10 Terrible

Christine

Traveled with family
Disliked: Cleanliness, amenities
The room was dingy, the furniture was stained, there were electrical chords and power strips hanging from the wall. There was no way to adjust the room temperature. There is a large parking lot light that could not be fully blocked.
Stayed 1 night in Dec 2025

6/10 Okay

Jean

Liked: Amenities
Everything was fine, as expected. Front staff was polite and helpful.
Stayed 1 night in Dec 2025

10/10 Excellent

Kenneth, Woodlawn

Stayed 2 nights in Jul 2025

8/10 Good

Rachel

Traveled with family
Liked: Staff & service
All good. Bed a little hard
Stayed 1 night in Dec 2025

8/10 Good

Shankar

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities
It was quite and comfortable stay
Stayed 1 night in Dec 2025

10/10 Excellent

Dev

Good
Stayed 1 night in Dec 2025

6/10 Okay

Shannon

Traveled with family and small children
Disliked: Cleanliness, property conditions & facilities
Staff was nice and room was clean. It's just an older hotel. It is not a town or hotel I will be back to that's for sure. Just a place to lay your head.
Stayed 1 night in Dec 2025

10/10 Excellent

Juan

Liked: Cleanliness, property conditions & facilities
Room and hotel was clean. Breakfast was great.
Stayed 1 night in Dec 2025

8/10 Good

Kathleen

Stayed 1 night in Dec 2025

10/10 Excellent

FREDERICK

Stayed 1 night in Dec 2025

10/10 Excellent

Patricia

Traveled with partner
Liked: Cleanliness, staff & service, property conditions & facilities
Room was spacious and nice size refrigerator Bathroom needed a remodel
Stayed 1 night in Dec 2025

10/10 Excellent

Judith, Miami

Traveled with family
Liked: Cleanliness, amenities, property conditions & facilities
The room was very clean I really liked
Stayed 1 night in Dec 2025

10/10 Excellent

Margarita

Liked: Cleanliness, staff & service, amenities
Overall nice room, friendly staff, and great breakfast. Very satisfied with my stay.
Stayed 1 night in Dec 2025

8/10 Good

Rich

Stayed 2 nights in Dec 2025

6/10 Okay

Jennifer

Disliked: Cleanliness, amenities, property conditions & facilities
Staff was courteous. Hotel is outdated but was a fine place for an overnight stop.
Stayed 2 nights in Dec 2025

10/10 Excellent

Mark, Ocean Pines

Liked: Cleanliness, amenities, property conditions & facilities
Staff was pleasant and helpful with restaurant information, room clean.
Stayed 1 night in Dec 2025

8/10 Good

Shawn

Traveled with family
Liked: Cleanliness, staff & service, amenities
Very kind staff and comfortable room
Stayed 1 night in Dec 2025

10/10 Excellent

Brandon

Stayed 1 night in Dec 2025

8/10 Good

Jon

Stayed 1 night in Nov 2025

8/10 Good

Kristina

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Breakfast had plenty of hot and cold options and was kept up. Room and lobby were clean and staff were friendly.
Stayed 1 night in Dec 2025

8/10 Good

Teresa S

Traveled with family
Liked: Cleanliness, staff & service, amenities
Room was very clean
Stayed 1 night in Dec 2025

6/10 Okay

James

Business traveler, Traveled with partner
Everything was just ok, I would have rated the hotel terrible on one reason No Hot Water! I ran it for 20 minutes and there was no Hot Water! Very disappointing would have complained but I was on a business trip and only slept in Hotel.
Stayed 2 nights in Dec 2025

8/10 Good

Patty

Liked: Cleanliness, property conditions & facilities
Clean room, nice accomodations overall. Very strict with breakfast buffet, my 13 and 10 year old grandkids couldn't eat until an adult came in, adult daughter couldn't wear slipper socks, had to go back to put on shoes. We were otw to a funeral and weren't in the mood for all the extra drama from kitchen staff.
Stayed 1 night in Nov 2025

8/10 Good

Steven, Pleasant Plain

Liked: Cleanliness, staff & service, property conditions & facilities
Everything was fine except the King size bed in our room. Mattress felt like it was wore out 10 years ago. Very lumpy, you could feel the springs. Told management when I checked out and they said would have maintenance check it out (??). My guess is, in the last 10 years, several guest have mentioned that and were probably given the same answer.
Stayed 1 night in Nov 2025

10/10 Excellent

Monica

Traveled with family
Liked: Cleanliness, amenities, property conditions & facilities
We like this location and have stayed here several times. We travel with our service dogs and this location has a nice outdoor area that is well lit at night for potty breaks. ***PLEASE NOTE…this hotel is NOT pet friendly. We will often seek out pet friendly facilities as a first option when we travel and this location comes up in the search. However upon arrival there’s a sign on the door that reads service animals only. I only mention it as a heads up. Our first stay we had prepaid for our room and if our dogs were not service animals we would have been in a bad situation as it was late when we arrived and would have had no place to go. Otherwise this is a great location and place to stay for us on our travels up and down I-95!
Stayed 1 night in Nov 2025