Deals on vacations and trips to Cairo

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Cairo flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
Comfort Suites Hopkinsville near Fort Campbell

Comfort Suites Hopkinsville near Fort Campbell

2.5 out of 5
Price was $523, price is now $487 per person
$487
per person
Oct 11 - Oct 13
found 22 hours ago
Roundtrip non-stop flight included
New York (JFK) to Paducah (PAH)
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
The Respite Bed and Breakfast

The Respite Bed and Breakfast

4.5 out of 5
Price was $957, price is now $878 per person
$878
per person
Nov 14 - Nov 17
found 11 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Paducah (PAH)
This bed & breakfast doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling on business? Take advantage of the express check-in, conference center, and conference space. A garden, express check-out, and laundry facilities are also on offer.
Holiday Inn Paducah Riverfront by IHG

Holiday Inn Paducah Riverfront by IHG

3 out of 5
Price was $970, price is now $901 per person
$901
per person
Nov 14 - Nov 17
found 11 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Paducah (PAH)
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Relax with a drink at the bar/lounge and enjoy perks like free self parking.
La Quinta Inn & Suites by Wyndham Paducah

La Quinta Inn & Suites by Wyndham Paducah

3 out of 5
Price was $896, price is now $833 per person
$833
per person
Nov 14 - Nov 17
found 11 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Paducah (PAH)
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free perks like buffet breakfast and free self parking.
The Lakehouse Inn at Sledd Creek

The Lakehouse Inn at Sledd Creek

2 out of 5
Price was $954, price is now $889 per person
$889
per person
Nov 14 - Nov 17
found 11 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Paducah (PAH)
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Families will appreciate the children's pool and onsite laundry facilities. Enjoy the seasonal outdoor pool and conveniences like a coffee shop and barbecue grills.

Top Cairo hotels deals

Quality Inn Cairo I-57

Quality Inn Cairo I-57

2.5 out of 5
13201 Kessler Road, Cairo, IL
Free Cancellation
Reserve now, pay when you stay
$68 nightly
The price is $76 total per night
$76 total
Oct 6 - Oct 7
Total with taxes and fees
This hotel features free WiFi in public areas, free newspapers, and free self parking. Enjoy the free full breakfast each morning. A picnic area is provided and the front desk is staffed around-the-clock.
Breakfast included
Pet friendly
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2 out of 5
310 S Story St, Charleston, MO
Free Cancellation
Reserve now, pay when you stay
$57 nightly
The price is $63 total per night
$63 total
Oct 2 - Oct 3
Total with taxes and fees
This motel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free on-the-go breakfast each morning. There's a computer station and multilingual staff can provide around-the-clock assistance.
Breakfast included
Pet friendly
Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake

$185 nightly
The price is $196 total per night
$196 total
Sep 7 - Sep 8
Total with taxes and fees
This cabin features barbecue grills.
Kitchen
Pet friendly
Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston

2.5 out of 5
102 Drake St, I-57 Exit 10, Charleston, MO
Free Cancellation
Reserve now, pay when you stay
$66 nightly
The price is $73 total per night
$73 total
Oct 6 - Oct 7
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business center and free internet in public areas. A safe deposit box is provided and the front desk is staffed around-the-clock.
Breakfast included
Pet friendly
Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake

$124 nightly
The price is $131 total per night
$131 total
Sep 6 - Sep 7
Total with taxes and fees
Stay at this cabin in Alexander County. Enjoy patios, an in-room coffeemaker, and air conditioning.
Air conditioning
Lake view
Welcome campers, hikers, fishermen, girls' weekend wine getaways!!

Welcome campers, hikers, fishermen, girls' weekend wine getaways!!

2 out of 5
Get rates
This vacation home features a garden, laundry facilities, and barbecue grills.
Kitchen
Washer
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See all available properties in Cairo
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Fort Defiance State Park

You can take time to visit Fort Defiance State Park during your travels to Cairo. Stroll along the riverfront or visit the churches while you're in the area.

Fort Defiance State Park

Frequently asked questions

How much are vacation packages to Cairo?
You'll be pleasantly surprised — you can find yourself in Cairo for just $487. Allow Travelocity to save you time and money with our awesome vacation package deals. With hotels, flights and tours all in one place, what are you waiting for?
Where can I get the best vacation package deals for Cairo?
With around 400 partner airlines and 1,000,000 hotels across the world, you can't beat Travelocity. Scroll through our impressive range and create the perfect package deal to Cairo. Doesn't it feel amazing when organizing a trip is that easy?
Why should I book my Cairo vacation package via Travelocity?
Nothing tops the satisfaction of knowing you've bagged the best price around — that's our Price Match Guarantee. Add to that our fantastic range of destinations and 24/7 team of customer service professionals and you've got the formula for a stress-free vacation.
Can I save on my Cairo car rental if I book it with hotels and flights?
With a Cairo vacation package, you can bundle your car, flight and hotel bookings and save some serious money. When you're ready to explore the best of this awesome city, why not make a beeline for Anheuser-Busch Brewery? This popular attraction is 120 mi from Cairo. With your own rental car, you'll be there in the blink of an eye.
Which airport is best for Cairo?
Williamson County Regional Airport (MWA) is 50 mi from downtown and is the beginning point for many memorable experiences. Alternatively, Cape Girardeau Municipal Airport (CGI) is 25 mi away from central Cairo and Barkley Regional Airport (PAH) is 25 mi away from central Cairo.
What is there to do in Cairo?
Click away at the excellent photo opportunities at Fort Defiance State Park, one of the most popular attractions in Cairo. There's a lot more to discover around this exciting city, so make sure you have enough time to visit some of its off-the-beaten-path gems.
Where should I stay when visiting Cairo?
The Quality Inn Cairo I-57 is popular with many visitors. Book soon to avoid missing out.

Photos of local treasures

Browse Cairo vacation photos for more inspiration