Cheap Flights to Lee County from $319 (2026/2027)

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How Much Does it Cost To Fly To Lee County?

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Wed, Mar 31 - Mon, Apr 5
LGA
LaGuardia
FLO
Florence Regional
$420 Roundtrip, found 18 hours ago
$420
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Wed, Mar 31 from LaGuardia to Florence Regional, returning Mon, Apr 5, priced at $420 found 18 hours ago
Wed, Mar 31 - Mon, Apr 5
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$420 Roundtrip, found 18 hours ago
$420
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Wed, Mar 31 from Newark Liberty Intl. Airport to Florence Regional, returning Mon, Apr 5, priced at $420 found 18 hours ago
Wed, Nov 18 - Tue, Nov 24
MCO
Orlando Intl.
FLO
Florence Regional
$457 Roundtrip, found 19 hours ago
$457
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Wed, Nov 18 from Orlando Intl. to Florence Regional, returning Tue, Nov 24, priced at $457 found 19 hours ago
Fri, May 7 - Mon, May 10
JFK
John F. Kennedy Intl.
FLO
Florence Regional
$477 Roundtrip, found 3 days ago
$477
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, May 7 from John F. Kennedy Intl. to Florence Regional, returning Mon, May 10, priced at $477 found 3 days ago
Wed, Mar 31 - Mon, Apr 5
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$500 Roundtrip, found 18 hours ago
$500
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Wed, Mar 31 from Newark Liberty Intl. Airport to Florence Regional, returning Mon, Apr 5, priced at $500 found 18 hours ago
Mon, Nov 16 - Mon, Nov 23
TPA
Tampa Intl.
FLO
Florence Regional
$525 Roundtrip, found 18 hours ago
$525
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Mon, Nov 16 from Tampa Intl. to Florence Regional, returning Mon, Nov 23, priced at $525 found 18 hours ago
Mon, Nov 16 - Mon, Nov 23
SRQ
Sarasota-Bradenton Intl.
FLO
Florence Regional
$525 Roundtrip, found 18 hours ago
$525
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Mon, Nov 16 from Sarasota-Bradenton Intl. to Florence Regional, returning Mon, Nov 23, priced at $525 found 18 hours ago
Wed, Nov 18 - Wed, Nov 25
MCO
Orlando Intl.
FLO
Florence Regional
$526 Roundtrip, found 19 hours ago
$526
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Wed, Nov 18 from Orlando Intl. to Florence Regional, returning Wed, Nov 25, priced at $526 found 19 hours ago
OriginDestinationTravel DatesFlights From*
DFWFlorenceOctober 21 to October 28$417
BOSFlorenceOctober 24 to October 31$490
LGAFlorenceSeptember 25 to September 27$630
LGAFlorenceSeptember 25 to September 27$630
PHLFlorenceSeptember 25 to September 27$651
BWIFlorenceSeptember 25 to September 27$688
*Prices include taxes and fees

Best Lee County Flight and Hotel Packages

Price found within the past 48 hours. Click for updated prices.
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5-star property

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Oct 15 - Oct 18

3 night stay

Minneapolis (MSP) to Florence (FLO)

Southwest Airlines • Non-stop roundtrip • Coach
Price was $977, price is now $971 per person
$971
per person
found 1 day ago
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Travelers ❤️ These Lee County 🏨

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Tilt Studio and Magnolia Mall are located nearby.
Opens in a new windowQuality Inn & Suites Florence Civic Center
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Dr. Eddie Floyd Tennis Center and CarolinaBank Field are located nearby.
Opens in a new windowPark Inn by Radisson Florence, SC
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Dr. Eddie Floyd Tennis Center and CarolinaBank Field are located nearby.
8.6/10 Excellent! (2,723 reviews)
"Comfortable bed. Noisy AC. Some bugs in the room. Not very nicely furnished. Coffee had no taste you get what you pay for. lol."

Reviewed on Sep 4, 2026

Opens in a new windowHoward Johnson by Wyndham Florence
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Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Florence Veterans Park and Magnolia Mall are located nearby.
Opens in a new windowComfort Inn & Suites Florence Center Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much is the cheapest flight to Lee County?
Within the last seven days, the cheapest roundtrip flight to Lee County cost $417 on our site. Browse our amazing deals, secure your tickets and start planning for your next trip. This price was available on Travelocity for flights to Lee County departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly to Lee County?
For the best chance at securing a great flight deal, time your break in March. According to Travelocity's direct flight demand from January to December last year, it's the most affordable time to fly to Lee County.
How can I check my flight status to Lee County?
"Trips" has you sorted when it comes to all things related to your flight to Lee County. Our handy portal lets you handle everything from one place, from looking up your flight status to seeing details about your hotel. Click on Trips at the top of the Travelocity homepage and then sign in. Or, download the Travelocity app and access your itinerary while you're out and about. Whether you've got the family flying with you or you're a solitary wanderer, all your bookings are at your fingertips.
How do I find the best deals on flights to Lee County?
Being flexible with your dates is one of the best ways to walk away with an awesome deal. Travelocity makes it super simple to find your ideal fare through the "Flexible dates" feature. Search for your flight to Lee County, then compare prices for surrounding dates by clicking the "Flexible dates" box at the top of the page. Booking ahead of schedule and flying outside of peak periods are other tips. In the last seven days, the lowest price for a roundtrip flight to Lee County was $417. This price was available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
Why should I book my flight to Lee County with Travelocity?
Look for cheap flights to Lee County with Travelocity and start organizing your next getaway. With round-the-clock customer service throughout every stage of the process and a Price Match Guarantee, we take the worry out of reserving cheap family flights, accommodations and more. Bag a superb deal today and prepare for a new adventure.
What are the most popular flight routes to Lee County?
Take a look at these top flight routes to Lee County and start organizing your dream escape:

  • Atlanta, GA (ATL-Hartsfield-Jackson Atlanta Intl.) to Charlotte-Douglas Intl. Airport (CLT) - 3,046 flights a month.
  • New York, NY (LGA-LaGuardia) to Charlotte-Douglas Intl. Airport (CLT) - 2,530 flights a month.
  • Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Charlotte-Douglas Intl. Airport (CLT) - 2,166 flights a month.

How much is a flight to Lee County on average?
Based on prices found over the last seven days, roundtrip flights to Lee County cost between $417 and $688. When you're ready to take off, Travelocity will help you find a fare that'll suit your budget. These prices were available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
How long is the average flight to Lee County?
Below are a handful of popular direct flights to Lee County along with their average flight duration:

  • Atlanta, GA (ATL-Hartsfield-Jackson Atlanta Intl.) to Charlotte-Douglas Intl. Airport (CLT) - 1 hour and 23 minutes
  • New York, NY (LGA-LaGuardia) to Charlotte-Douglas Intl. Airport (CLT) - 2 hours and 8 minutes
  • Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Charlotte-Douglas Intl. Airport (CLT) - 2 hours and 2 minutes

What can I expect on a flight to Lee County?
How long your flight takes and whether you fly with a full-service or budget carrier play a major role. If you're looking for long-haul flights to Lee County, drinks, food and entertainment will come standard. Wondering about cheap flights for family vacations? Check out the fares with low-cost carriers. Generally, these airlines don't offer as many inclusions, or you'll have to pay a fee for them.