Cheap Flights to Lee County from $342 (2026/2027)

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How Much Does it Cost To Fly To Lee County?

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Wed, Mar 31 - Mon, Apr 5
JFK
John F. Kennedy Intl.
FLO
Florence Regional
$440 Roundtrip, found 1 day ago
$440
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Mar 31 from John F. Kennedy Intl. to Florence Regional, returning Mon, Apr 5, priced at $440 found 1 day ago
Wed, Dec 30 - Thu, Dec 31
LGA
LaGuardia
FLO
Florence Regional
$440 Roundtrip, found 10 hours ago
$440
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Wed, Dec 30 from LaGuardia to Florence Regional, returning Thu, Dec 31, priced at $440 found 10 hours ago
Wed, Mar 31 - Mon, Apr 5
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$440 Roundtrip, found 1 day ago
$440
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Mar 31 from Newark Liberty Intl. Airport to Florence Regional, returning Mon, Apr 5, priced at $440 found 1 day ago
Sun, Nov 22 - Wed, Nov 25
SBY
Salisbury - Ocean City Wicomico Regional
FLO
Florence Regional
$546 Roundtrip, found 11 hours ago
$546
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Sun, Nov 22 from Salisbury - Ocean City Wicomico Regional to Florence Regional, returning Wed, Nov 25, priced at $546 found 11 hours ago
Sun, Nov 22 - Sat, Nov 28
MDT
Harrisburg Intl.
FLO
Florence Regional
$557 Roundtrip, just found
$557
Roundtrip
just found
Select American Airlines flight, departing Sun, Nov 22 from Harrisburg Intl. to Florence Regional, returning Sat, Nov 28, priced at $557 just found
Mon, Dec 21 - Tue, Dec 29
IND
Indianapolis Intl.
FLO
Florence Regional
$578 Roundtrip, found 6 hours ago
$578
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Mon, Dec 21 from Indianapolis Intl. to Florence Regional, returning Tue, Dec 29, priced at $578 found 6 hours ago
Sat, Oct 24 - Sat, Oct 31
DTW
Detroit Metropolitan Wayne County
FLO
Florence Regional
$584 Roundtrip, found 1 day ago
$584
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Oct 24 from Detroit Metropolitan Wayne County to Florence Regional, returning Sat, Oct 31, priced at $584 found 1 day ago
Wed, Nov 18 - Tue, Dec 1
BGR
Bangor Intl.
FLO
Florence Regional
$631 Roundtrip, found 1 day ago
$631
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Nov 18 from Bangor Intl. to Florence Regional, returning Tue, Dec 1, priced at $631 found 1 day ago
OriginDestinationTravel DatesFlights From*
DFWFlorenceDecember 29 to January 5$431
LGAFlorenceDecember 30 to December 31$440
LGAFlorenceDecember 30 to December 31$440
EWRFlorenceNovember 6 to November 8$506
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
LAXFlorenceOctober 16 to October 21$639
*Prices include taxes and fees

Best Lee County Flight and Hotel Packages

Price found within the past 48 hours. Click for updated prices.
La Quinta Inn & Suites by Wyndham Florence
3.0-star property

La Quinta Inn & Suites by Wyndham Florence

Dec 29 - Jan 2

4 night stay

Rochester (ROC) to Florence (FLO)

American Airlines • Roundtrip • Coach
Price was $1,038, price is now $991 per person
$991
per person
found 21 hours ago
TownePlace Suites by Marriott Florence
3.0-star property

TownePlace Suites by Marriott Florence

Dec 29 - Jan 2

4 night stay

Rochester (ROC) to Florence (FLO)

American Airlines • Roundtrip • Coach
Price was $1,101, price is now $1,054 per person
$1,054
per person
found 21 hours ago
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Travelers ❤️ These Lee County 🏨

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Dr. Eddie Floyd Tennis Center and CarolinaBank Field are located nearby.
9/10 Wonderful! (2,465 reviews)
"Clean room, the breakfast was great!"

Reviewed on Oct 12, 2026

Opens in a new windowPark Inn by Radisson Florence, SC
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Dr. Eddie Floyd Tennis Center and CarolinaBank Field are located nearby.
8.6/10 Excellent! (2,752 reviews)
"Excellent hotel! Will stay again."

Reviewed on Oct 11, 2026

Opens in a new windowHoward Johnson by Wyndham Florence
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Florence Veterans Park and Magnolia Mall are located nearby.
Opens in a new windowComfort Inn & Suites Florence Center Area
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Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Dr. Eddie Floyd Tennis Center and CarolinaBank Field are located nearby.
Opens in a new windowSpark by Hilton Florence North I-95, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much is the cheapest flight to Lee County?
Within the last seven days, the cheapest roundtrip flight to Lee County cost $431 on our site. Browse our amazing deals, secure your tickets and start planning for your next trip. This price was available on Travelocity for flights to Lee County departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly to Lee County?
For the best chance at securing a great flight deal, time your break in March. According to Travelocity's direct flight demand from January to December last year, it's the most affordable time to fly to Lee County.
How can I check my flight status to Lee County?
"Trips" has you sorted when it comes to all things related to your flight to Lee County. Our handy portal lets you handle everything from one place, from looking up your flight status to seeing details about your hotel. Click on Trips at the top of the Travelocity homepage and then sign in. Or, download the Travelocity app and access your itinerary while you're out and about. Whether you've got the family flying with you or you're a solitary wanderer, all your bookings are at your fingertips.
How do I find the best deals on flights to Lee County?
Being flexible with your dates is one of the best ways to walk away with an awesome deal. Travelocity makes it super simple to find your ideal fare through the "Flexible dates" feature. Search for your flight to Lee County, then compare prices for surrounding dates by clicking the "Flexible dates" box at the top of the page. Booking ahead of schedule and flying outside of peak periods are other tips. In the last seven days, the lowest price for a roundtrip flight to Lee County was $431. This price was available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
Why should I book my flight to Lee County with Travelocity?
Look for cheap flights to Lee County with Travelocity and start organizing your next getaway. With round-the-clock customer service throughout every stage of the process and a Price Match Guarantee, we take the worry out of reserving cheap family flights, accommodations and more. Bag a superb deal today and prepare for a new adventure.
What are the most popular flight routes to Lee County?
Take a look at these top flight routes to Lee County and start organizing your dream escape:

  • Atlanta, GA (ATL-Hartsfield-Jackson Atlanta Intl.) to Charlotte-Douglas Intl. Airport (CLT) - 3,046 flights a month.
  • New York, NY (LGA-LaGuardia) to Charlotte-Douglas Intl. Airport (CLT) - 2,530 flights a month.
  • Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Charlotte-Douglas Intl. Airport (CLT) - 2,166 flights a month.

How much is a flight to Lee County on average?
Based on prices found over the last seven days, roundtrip flights to Lee County cost between $431 and $639. When you're ready to take off, Travelocity will help you find a fare that'll suit your budget. These prices were available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
How long is the average flight to Lee County?
Below are a handful of popular direct flights to Lee County along with their average flight duration:

  • Atlanta, GA (ATL-Hartsfield-Jackson Atlanta Intl.) to Charlotte-Douglas Intl. Airport (CLT) - 1 hour and 23 minutes
  • New York, NY (LGA-LaGuardia) to Charlotte-Douglas Intl. Airport (CLT) - 2 hours and 8 minutes
  • Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Charlotte-Douglas Intl. Airport (CLT) - 2 hours and 2 minutes

What can I expect on a flight to Lee County?
How long your flight takes and whether you fly with a full-service or budget carrier play a major role. If you're looking for long-haul flights to Lee County, drinks, food and entertainment will come standard. Wondering about cheap flights for family vacations? Check out the fares with low-cost carriers. Generally, these airlines don't offer as many inclusions, or you'll have to pay a fee for them.