Book Hotels in Cherokee, AL
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Top Cherokee hotels

Driftwood Retreat on Tennessee River/Pickwick Lake
Cherokee AL
This vacation home features a garden, laundry facilities, and barbecue grills.
Great week at this lakeside cabin just above Koger Island. Easy walk down to the water, good driveway, boat ramps nearby. Nicely equipped and everything works. We would definitely stay there again.
Reviewed on Apr 21, 2026

RIVERTON LAKESIDE COTTAGE ON PICKWICK LAKE
Cherokee AL
This vacation home featured laundry facilities and barbecue grills.
I stayed there because I came for a fishing trip and I love the house coming back for more fishing and i plan to stay there every time I come there great place
Reviewed on Apr 21, 2026

Renaissance Shoals Resort & Spa
10 Hightower Place Florence AL
Fully refundableReserve now, pay when you stay
$269 nightly
The price is $309 total per night from May 3 to May 4
$309 total
May 3 - May 4
Total with taxes and fees
A full-service spa, 2 restaurants, and 2 hot tubs are all featured at this smoke-free resort. Traveling on business? Take advantage of the free WiFi in public ...
Very good staff, nice property, clean rooms. Roomkey devices were finicky, great bar and pool area. Honestly the only real issue is the 1ply paper —. You would think for the nightly price they could find 50c for better paper
Reviewed on Apr 19, 2026

The Stricklin Hotel
317 N Court St Florence AL
Fully refundableReserve now, pay when you stay
$197 nightly
The price is $218 total per night from Apr 26 to Apr 27
$218 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features 2 restaurants and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free ...
Breakfast next door was amazing!
Reviewed on Apr 21, 2026

Spark by Hilton Tuscumbia Muscle Shoals
712 Hwy 72 W Tuscumbia AL
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $103 total per night from Apr 30 to May 1
$103 total
Apr 30 - May 1
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Images on hotels.com were not what we got when we got there. As the hotel had just been bought out by Spark. Everything was new. On our second day., breakfast changed, we no longer had the option of protein for breakfast as that was removed. We could pay for it. Staff did not know how to operate ...
Reviewed on Apr 24, 2026

Rustic Cabin overlooking Pickwick Lake
Cherokee AL
This vacation home featured laundry facilities and barbecue grills.
This place is very convenient for us when visiting. Thanks Pam!
Reviewed on Mar 22, 2026

Days Inn by Wyndham Muscle Shoals Florence
2701 Woodward Ave Muscle Shoals AL
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $81 total per night from May 3 to May 4
$81 total
May 3 - May 4
Total with taxes and fees
A gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like full breakfast and WiFi in public areas. ...
Beds were comfortable and the breakfast was fine, but the room definitely smelled like cigarette smoke and the AC has trouble getting the room cool enough. Still, not a bad stay for the money.
Reviewed on Apr 23, 2026

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
1852 Highway 72 E Tuscumbia AL
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $84 total per night from May 2 to May 3
$84 total
May 2 - May 3
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
had a funky smell in the lobby but other than that it was worth the money if your on a tight budget.
Reviewed on Apr 23, 2026

Clarion Inn Sheffield Muscle Shoals
4900 Hatch Blvd Sheffield AL
Fully refundable
$86 nightly
The price is $96 total per night from Apr 30 to May 1
$96 total
Apr 30 - May 1
Total with taxes and fees
A nightclub and a restaurant are featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Yes
Reviewed on Apr 20, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Cherokee hotel reviews by fellow wanderers

Spark by Hilton Tuscumbia Muscle Shoals
4 out of 5
Posted 8 hours ago
Travelocity Verified Review
"Images on hotels.com were not what we got when we got there. As the hotel had just been bought out by Spark. Everything was new. On our second day., breakfast changed, we no longer had the option of protein for breakfast as that was removed. We could pay for it. Staff did not know how to operate the air-conditioning units in the room, it was new. We wanted the fan to blow for noise, that could not be done. There was no coffee maker in the room as it was removed from the rooms as Spark does not provide coffee makers in the rooms. We were staying there for the historic aspect and not prepared for the change. We would have stayed closer to the golf course if we would have known.
But, it was clean, new, great staff, easy location. I feel Spark should have called to prepare us for the construction and changes."
A verified traveler stayed at Spark by Hilton Tuscumbia Muscle Shoals
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