Explore top 2025 5 Star Hotels in Santorini

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Top Santorini 5 Star hotels

De Sol Spa Hotel

Fira Santorini Santorini Island

Fully refundableReserve now, pay when you stay

$206 nightly

$238 total

Nov 28 - Nov 29

Total with taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free ...

9.2/10 Wonderful! (524 reviews)

Very good staff.

Reviewed on Nov 14, 2025

Suites of the Gods Cave Spa

Caldera Santorini Santorini Island

Fully refundableReserve now, pay when you stay

$133 nightly

$156 total

Dec 2 - Dec 3

Total with taxes and fees

A full-service spa and a restaurant are featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and free perks like buffet breakfast and free self ...

8.6/10 Excellent! (292 reviews)

Other than a little misunderstanding due to communication issues the staff was very professional and we got to meet other guests we had a driver George not sure if that’s how he spells his name but he was amazingly professional thumbs up! I would definitely stay there again

Reviewed on Oct 26, 2025

Aqua Luxury Suites

Imerovigli Santorini Santorini Island

$164 nightly

$187 total

Dec 9 - Dec 10

Total with taxes and fees

A full-service spa, a hot tub, and a restaurant are all featured at this luxury aparthotel. Unwind with a drink at the bar/lounge and enjoy perks like free breakfast ...

9.2/10 Wonderful! (211 reviews)

Oskana and Elena were absolutely great. They offered good advice and made everything very simple. It was a delight staying here. Only regret was we didn't stay longer. The ocean view was unmatched and at the same time it allowed an amazing back drop of the city.

Reviewed on Sep 27, 2025

Canaves Oia Suites - Small Luxury Hotels of the World

Oia city Santorini Santorini Island

A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Enjoy the gym and free perks like full breakfast and free self parking. Enjoy ...

9.6/10 Exceptional! (134 reviews)

Canaves Oua Suites exceeded our expectations. Suite was fabulous with more than enough room and amenities. The view was… I can’t describe it. Facing the Caldera and we could see the sunset. Love!

Reviewed on Oct 27, 2025

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Astro Palace Hotel & Spa

Eikostis Pemptis Martiou Santorini Santorini Island

A full-service spa, 2 restaurants, and an indoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public ...

9.2/10 Wonderful! (735 reviews)

My husband and I stayed at this hotel with our 3-month-old baby for 2 nights — and immediately wished we had booked a longer stay. From the moment we arrived, the staff went above and beyond to make us feel welcome. We've travelled a lot around the world, but the reception team here truly stood out ...

Reviewed on Oct 19, 2025

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Canaves Epitome - Small Luxury Hotels of the World

Eparchiaki Odos Oia Santorini Santorini Island

A full-service spa, 2 restaurants, and 2 outdoor pools are all featured at this luxury hotel. Enjoy the gym and free perks like full breakfast and free self ...

9.8/10 Exceptional! (163 reviews)

Outstanding hotel, outstanding property, outstanding service, and staff

Reviewed on Oct 5, 2025

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Grace Hotel, Auberge Collection

Imerovigli Santorini Santorini Island

An attached winery, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the outdoor pool and free perks like full breakfast and ...

9.6/10 Exceptional! (133 reviews)

Property was stunning - be warned it’s a walk to the property on the walking route and you will get your stair workout - but it’s so worth it. Our junior suite was perfect, beautifully detailed and the view is incredible. Less crowded than Fira or Oia, quiet, lovely. Be sure to go to Avocado restaurant ...

Reviewed on Oct 5, 2025

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Santorini Princess Spa Hotel

Imerovigli Santorini Santorini Island

A full-service spa, a hot tub, and a restaurant are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and free perks like buffet breakfast ...

9.8/10 Exceptional! (999 reviews)

Most incredible place we have stayed. The location is ideal and the views from our room were stunning. Staff are very attentive. Would recommend!!

Reviewed on Nov 15, 2025

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Katikies Santorini - The Leading Hotels Of The World

Oia Santorini Santorini Island

A full-service spa, 3 restaurants, and 3 outdoor pools are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public ...

9.6/10 Exceptional! (373 reviews)

Phenomenal all the way around. Beautiful, exquisite, excellent 👌

Reviewed on Oct 23, 2025

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Sandblu

Kamari Santorini Santorini Island

A full-service spa, 2 restaurants, and 2 outdoor pools are all featured at this luxury hotel. Relax with a drink at one of the 2 poolside bars and enjoy free ...

10/10 Exceptional! (62 reviews)

Amazing hotel and staff. 5 stars all around.

Reviewed on Nov 9, 2025

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Santorini Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Santorini to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Santorini 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Santorini before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Santorini hotel reviews by fellow wanderers

Hotel Santorini

5 out of 5

Posted 3 days ago

Travelocity Verified Review

"Excellent, friendly & helpful service staff always ready to render any help. Unbeatable location next to the bus station and near to the Caldera & main square where many eateries are at. Very reliable house keeping daily. They do their best! Note: Do bring along a pair of rubber slippers for use in the washroom. This hotel would be my choice again. "

A verified traveler stayed at Hotel Santorini