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Top Santorini 5 Star hotels

Cresanto Luxury Suites

Cresanto Luxury Suites

5 out of 5
Imerovigli Santorini
$190 nightly
The price is $233 total per night from Apr 17 to Apr 18
$233 total
Apr 17 - Apr 18
Total with taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Enjoy the seasonal outdoor pool and perks like free self parking and free ...
9.6/10 Exceptional! (302 reviews)
Front desk staff was unfriendly and not willing to help when we had an issue

Reviewed on Jan 26, 2026

Opens in a new windowCresanto Luxury Suites
Katikies Santorini – Pelagos House - The Leading Hotels of the World

Katikies Santorini – Pelagos House - The Leading Hotels of the World

5 out of 5
Oia Santorini Santorini Island
Fully refundableReserve now, pay when you stay
$473 nightly
The price is $554 total per night from Apr 4 to Apr 5
$554 total
Apr 4 - Apr 5
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor pools are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public ...
Opens in a new windowKatikies Santorini – Pelagos House - The Leading Hotels of the World
Andronis Arcadia Hotel

Andronis Arcadia Hotel

5 out of 5
Oia Santorini Santorini Island
$847 nightly
The price is $979 total per night from May 4 to May 5
$979 total
May 4 - May 5
Total with taxes and fees
A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Relax with a drink at one of the 2 poolside bars and enjoy free perks like ...
9.6/10 Exceptional! (198 reviews)
Amazing staff, such great hospitality and very accommodating to all our needs. Property is absolutely beautiful, very clean and luxurious!

Reviewed on Oct 24, 2025

Opens in a new windowAndronis Arcadia Hotel
Sea Breeze Santorini Beach Resort, Curio Collection Hilton

Sea Breeze Santorini Beach Resort, Curio Collection Hilton

5 out of 5
Exomitis Perivolos Santorini Santorini Island
$160 nightly
The price is $196 total per night from May 1 to May 2
$196 total
May 1 - May 2
Total with taxes and fees
This luxury resort features a full-service spa, 4 outdoor pools, and a restaurant. Relax with free beach cabanas and sun loungers, and cool off with a drink ...
9.8/10 Exceptional! (62 reviews)
Our stay here was amazing. The resort and location is beautiful. We saw amazing sunsets, had delicious food and great service. I would highly recommend this resort.

Reviewed on Oct 27, 2025

Opens in a new windowSea Breeze Santorini Beach Resort, Curio Collection Hilton
Andronis Luxury Suites

Andronis Luxury Suites

5 out of 5
Oia Santorini Santorini Island
$828 nightly
The price is $958 total per night from Apr 26 to Apr 27
$958 total
Apr 26 - Apr 27
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy the hot tub and free perks like full breakfast and WiFi ...
9.8/10 Exceptional! (238 reviews)
Amazing Luxurious Santorini Hotel !
We had an amazing hotel stay at the Andronis Luxury Suites. The room was large, comfortable bed , large bathrooms and large area for a closet . The views are simply SPECTACULAR! We had a private pool and after a long day exploring Oia it was the perfect way to unwind and cool off. The staff was also ...

Reviewed on Sep 24, 2025

Opens in a new windowAndronis Luxury Suites
Lilium Hotel

Lilium Hotel

5 out of 5
Fira Town Santorini Santorini Island
$132 nightly
The price is $168 total per night from Apr 9 to Apr 10
$168 total
Apr 9 - Apr 10
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...
9.6/10 Exceptional! (818 reviews)
We were extremely disappointed with our selection of hotel. First, the rates we paid booking 5 weeks in advance were double what rooms cost once we got there. We were the few customers staying before closing for the season and everything was removed from the premises, from cushions, to the ability ...

Reviewed on Oct 23, 2025

Opens in a new windowLilium Hotel
NOŪS Santorini

NOŪS Santorini

5 out of 5
Mesaria Santorini Santorini Island
$284 nightly
The price is $339 total per night from Apr 27 to Apr 28
$339 total
Apr 27 - Apr 28
Total with taxes and fees
A full-service spa, 2 restaurants, and a gym are all featured at this luxury resort. Enjoy the steam room and free perks like full breakfast and free self parking. ...
Opens in a new windowNOŪS Santorini
Art Maisons Aspaki Exclusive Suites

Art Maisons Aspaki Exclusive Suites

5 out of 5
Oia Santorini Santorini Island
$485 nightly
The price is $568 total per night from Apr 27 to Apr 28
$568 total
Apr 27 - Apr 28
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Enjoy the sauna and free perks like cooked-to-order breakfast and ...
9.8/10 Exceptional! (125 reviews)
Great stay

Reviewed on Mar 28, 2026

Opens in a new windowArt Maisons Aspaki Exclusive Suites
Santo Pure Oia Suites & Villas

Santo Pure Oia Suites & Villas

5 out of 5
Oia Santorini
$282 nightly
The price is $337 total per night from Apr 27 to Apr 28
$337 total
Apr 27 - Apr 28
Total with taxes and fees
A full-service spa, 6 outdoor pools, and a hot tub are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free ...
9.6/10 Exceptional! (508 reviews)
The entire staff made us feel welcomed and they made our trip very enjoyable. The room was very clean and private.

Reviewed on Nov 5, 2025

Opens in a new windowSanto Pure Oia Suites & Villas
Suites of the Gods Cave Spa

Suites of the Gods Cave Spa

5 out of 5
Caldera Santorini Santorini Island
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $136 total per night from Apr 18 to Apr 19
$136 total
Apr 18 - Apr 19
Total with taxes and fees
A full-service spa and a restaurant are featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and free perks like buffet breakfast and free self ...
8.6/10 Excellent! (300 reviews)
The female who checked us in tried to offer us a basic room and only after much objection did we get something similar to what we paid for and booked so we were not happy but accepted as we didnt want to spoil our holiday. This female continued to be a problem so we blocked her, everyone else in ...

Reviewed on Mar 30, 2026

Opens in a new windowSuites of the Gods Cave Spa
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santorini Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Santorini to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Santorini 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Santorini before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

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