Explore top 2025 5 Star Hotels in Santorini

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Top Santorini 5 Star hotels

De Sol Spa Hotel

De Sol Spa Hotel

5 out of 5
Fira, Santorini, Santorini Island
Fully refundableReserve now, pay when you stay
$249 nightly
The price is $287 total per night from Nov 15 to Nov 16
$287 total
Nov 15 - Nov 16
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free ...
9.2/10 Wonderful! (523 reviews)
Clean rooms and great staff

Reviewed on Nov 5, 2025

Opens in a new windowDe Sol Spa Hotel
Canaves Oia Suites - Small Luxury Hotels of the World

Canaves Oia Suites - Small Luxury Hotels of the World

5 out of 5
Oia city, Santorini, Santorini Island
A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Enjoy the gym and free perks like full breakfast and free self parking. Enjoy ...
9.6/10 Exceptional! (134 reviews)
Canaves Oua Suites exceeded our expectations. Suite was fabulous with more than enough room and amenities. The view was… I can’t describe it. Facing the Caldera and we could see the sunset. Love!

Reviewed on Oct 27, 2025

Opens in a new windowCanaves Oia Suites - Small Luxury Hotels of the World
Santo Pure Oia Suites & Villas

Santo Pure Oia Suites & Villas

5 out of 5
Oia, Santorini
A full-service spa, 6 outdoor pools, and a hot tub are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public areas, ...
9.4/10 Exceptional! (503 reviews)
The entire staff made us feel welcomed and they made our trip very enjoyable. The room was very clean and private.

Reviewed on Nov 5, 2025

Opens in a new windowSanto Pure Oia Suites & Villas
The Majestic Hotel

The Majestic Hotel

5 out of 5
Fira, Santorini, Santorini Island
This smoke-free hotel features 2 restaurants, a bar/lounge, and a gym. There's fun for all ages with a children's pool and a playground, and families will appreciate ...
9/10 Wonderful! (549 reviews)
Friendliest staff ever, lovely and quiet in October, immaculately clean, great breakfast, complimentary bottle of fizz with our Expedia booking and less than 10 minutes walk to Fira. We booked a Caldera view … didn’t realise that also overlooked the road so if we stay again I’ll book a non-Caldera ...

Reviewed on Oct 31, 2025

Opens in a new windowThe Majestic Hotel
Grace Hotel, Auberge Collection

Grace Hotel, Auberge Collection

5 out of 5
Imerovigli, Santorini, Santorini Island
An attached winery, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the outdoor pool and free perks like full breakfast and ...
9.6/10 Exceptional! (133 reviews)
Property was stunning - be warned it’s a walk to the property on the walking route and you will get your stair workout - but it’s so worth it. Our junior suite was perfect, beautifully detailed and the view is incredible. Less crowded than Fira or Oia, quiet, lovely. Be sure to go to Avocado restaurant ...

Reviewed on Oct 5, 2025

Opens in a new windowGrace Hotel, Auberge Collection
Katikies Garden Santorini - The Leading Hotels Of The World

Katikies Garden Santorini - The Leading Hotels Of The World

5 out of 5
Fira Town, Santorini
This luxury hotel features a full-service spa and a restaurant. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and ...
9.2/10 Wonderful! (94 reviews)
Truly a unique experience Its a true 5 star / 5 diamond property Place to stay on Santorini

Reviewed on Oct 27, 2025

Opens in a new windowKatikies Garden Santorini - The Leading Hotels Of The World
Andronis Arcadia Hotel

Andronis Arcadia Hotel

5 out of 5
Oia, Santorini, Santorini Island
A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Relax with a drink at one of the 2 poolside bars and enjoy free perks like ...
9.6/10 Exceptional! (197 reviews)
Amazing staff, such great hospitality and very accommodating to all our needs. Property is absolutely beautiful, very clean and luxurious!

Reviewed on Oct 24, 2025

Opens in a new windowAndronis Arcadia Hotel
Canaves Epitome - Small Luxury Hotels of the World

Canaves Epitome - Small Luxury Hotels of the World

5 out of 5
Eparchiaki Odos Oia, Santorini, Santorini Island
A full-service spa, 2 restaurants, and 2 outdoor pools are all featured at this luxury hotel. Enjoy the gym and free perks like full breakfast and free self ...
9.8/10 Exceptional! (162 reviews)
Outstanding hotel, outstanding property, outstanding service, and staff

Reviewed on Oct 5, 2025

Opens in a new windowCanaves Epitome - Small Luxury Hotels of the World
Aqua Luxury Suites

Aqua Luxury Suites

5 out of 5
Imerovigli, Santorini, Santorini Island
$237 nightly
The price is $270 total per night from Nov 26 to Nov 27
$270 total
Nov 26 - Nov 27
Total with taxes and fees
A full-service spa, a hot tub, and a restaurant are all featured at this luxury aparthotel. Unwind with a drink at the bar/lounge and enjoy perks like free breakfast ...
9.2/10 Wonderful! (210 reviews)
Oskana and Elena were absolutely great. They offered good advice and made everything very simple. It was a delight staying here. Only regret was we didn't stay longer. The ocean view was unmatched and at the same time it allowed an amazing back drop of the city.

Reviewed on Sep 27, 2025

Opens in a new windowAqua Luxury Suites
Radisson Blu Zaffron Resort, Santorini

Radisson Blu Zaffron Resort, Santorini

5 out of 5
Apollonos & Makedonias str., Kamari, Santorini, Santorini
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and airport ...
9.6/10 Exceptional! (158 reviews)
The hotel is very convenient and walkable to the black sand beach and many stores and dining options, love the location. Staff friendly and helpful... transportation thru hotel is very costly but dependable.

Reviewed on Oct 26, 2025

Opens in a new windowRadisson Blu Zaffron Resort, Santorini
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Santorini Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Santorini to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Santorini 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Santorini before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

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