Explore top 2025 5 Star Hotels in Medellin

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Top Medellin 5 Star hotels

NH Collection Medellín Royal

NH Collection Medellín Royal

5 out of 5
Carrera 42 No 5 Sur 130, El Poblado, Medellín, Antioquia
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $85 total per night from Nov 2 to Nov 3
$85 total
Nov 2 - Nov 3
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9/10 Wonderful! (1,018 reviews)
Lovely clean hotel with very helpful, friendly and responsive staff in a safe area of Medellin, within easy walking distance of the metro, as well as several restaurants if you don’t want to go too far afield.

Reviewed on Oct 20, 2025

Opens in a new windowNH Collection Medellín Royal
The Click Clack Hotel Medellin

The Click Clack Hotel Medellin

5 out of 5
Calle 10B # 37-29, Medellín, Antioquia
Fully refundableReserve now, pay when you stay
$167 nightly
The price is $167 total per night from Oct 27 to Oct 28
$167 total
Oct 27 - Oct 28
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and airport shuttle. ...
9.2/10 Wonderful! (1,036 reviews)
Home away from home.

Reviewed on Oct 20, 2025

Opens in a new windowThe Click Clack Hotel Medellin
Medellin Marriott Hotel

Medellin Marriott Hotel

5 out of 5
Calle 1a Sur #43a-83, Medellín
Fully refundableReserve now, pay when you stay
$289 nightly
The price is $289 total per night from Oct 24 to Oct 25
$289 total
Oct 24 - Oct 25
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
8.8/10 Excellent! (574 reviews)
Muy placentera y amable el personal del hotel

Reviewed on Aug 24, 2025

Opens in a new windowMedellin Marriott Hotel
Luxury Suites Prana By Cadissa

Luxury Suites Prana By Cadissa

5 out of 5
Calle 35 # 63B-36, Medellín, Antioquia
Fully refundableReserve now, pay when you stay
$245 nightly
The price is $245 total per night from Oct 28 to Oct 29
$245 total
Oct 28 - Oct 29
This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling on business? Take advantage of the laundry service and ...
9.2/10 Wonderful! (33 reviews)
Stayed here with my husband, 3 bedroom apartment was beautiful, front desk is helpful with check in, never could get the tv in my room to actually work and the WiFi connection isn’t strong at all, especially in the rooms…. My only major complaint is on July 19th my husband booked this property for ...

Reviewed on Sep 21, 2025

Opens in a new windowLuxury Suites Prana By Cadissa
Wake BioHotel

Wake BioHotel

5 out of 5
25115 Calle 2 Sur, Medellín, Antioquia
Fully refundableReserve now, pay when you stay
$250 nightly
The price is $250 total per night from Nov 3 to Nov 4
$250 total
Nov 3 - Nov 4
This aparthotel features 2 coffee shops/cafes and an outdoor pool. Enjoy the 24-hour gym and free perks like buffet breakfast and WiFi in public areas. You'll ...
8.4/10 Very Good! (11 reviews)
This place has been the absolute best! From the esthetics, staff and food! Any issues were immediately addressed and handled!! I would most def recommend. ⭐️⭐️⭐️⭐️⭐️

Reviewed on Sep 7, 2025

Opens in a new windowWake BioHotel
Morph by MOME Stays

Morph by MOME Stays

5 out of 5
Calle 1 #35 - 70, Medellín, Antioquia
$649 nightly
The price is $649 total per night from Oct 29 to Oct 30
$649 total
Oct 29 - Oct 30
This hotel features an outdoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Free self parking, a garden, and a communal ...
10/10 Exceptional! (1 review)
Aa

Reviewed on Aug 15, 2025

Opens in a new windowMorph by MOME Stays
30 Living Suites

30 Living Suites

5 out of 5
82C-40 Cl. 30, Medellín, Antioquia
This apartment doesn't skimp on freebies - guests receive free full breakfast and free WiFi. Traveling on business? Take advantage of the business center, conference ...
8.8/10 Excellent! (149 reviews)
Great

Reviewed on Jun 13, 2025

Opens in a new window30 Living Suites
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Medellin Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Medellin to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Medellin 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Medellin before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

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