Explore top 2026 4 Star Hotels in Odessa

Name: DoubleTree by Hilton Midland West Loop I-250
Price range: $180 total

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Top Odessa 4 Star hotels

Wyndham Midland Downtown

117 West Wall Street Midland TX

Fully refundableReserve now, pay when you stay

$74 nightly

$85 total

Sep 17 - Sep 18

Total with taxes and fees

The hotel's outdoor pool, 24-hour gym, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the 24-hour business center, ...

8/10 Very Good! (999 reviews)

"This hotel was old and ghetto. It looks nice in the pictures but it is not!!! The bathroom was still dirty, especially the tub. Leftover bars of soap build up on the soap shelf, the door didnt open all the way it got stuck on thr toilet. The towels were disgusting! Our sliding glass door was taped ..."

Reviewed on Sep 13, 2026

Odessa Marriott Hotel & Conference Center

305 East 5th Street Odessa TX

Fully refundableReserve now, pay when you stay

$182 nightly

$209 total

Sep 18 - Sep 19

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

DoubleTree by Hilton Midland West Loop I-250

1403 North Loop 250 West Midland TX

Fully refundableReserve now, pay when you stay

$158 nightly

$180 total

Sep 20 - Sep 21

Total with taxes and fees

This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Odessa

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Odessa 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Odessa will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Odessa, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.