Explore top 2026 4 Star Hotels in Florida Keys
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Top Florida Keys 4 Star hotels
Reefhouse Resort & Marina
103800 Overseas Hwy Key Largo FL
Fully refundableReserve now, pay when you stay
$299 nightly
The price is $331 total per night from May 21 to May 22
$331 total
May 21 - May 22
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Family-friendly ...
9.4/10 Exceptional! (1,440 reviews)
"Our room was clean and well appointed. Walking distance to some local bars with entertainment. Pool was beautiful. Our only complaint was the terrible bartender in the upstairs lounge."
Reviewed on May 19, 2026
Hawks Cay Resort
61 Hawks Cay Blvd Marathon FL
Fully refundableReserve now, pay when you stay
$334 nightly
The price is $375 total per night from Jun 14 to Jun 15
$375 total
Jun 14 - Jun 15
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...
8.2/10 Very Good! (1,011 reviews)
"All in all a good place to stay for the family. Grades: -Pools: Family and adult pools were available throughout the day, in good condition, and well serviced by the nearby tiki bar. (Grade A) -Service: Service in the overall resort depended on who you encountered. Some front desk members were quite ..."
Reviewed on May 19, 2026
Baker's Cay Resort Key Largo, Curio Collection by Hilton
97000 Overseas Hwy Key Largo FL
$327 nightly
The price is $368 total per night from Jun 16 to Jun 17
$368 total
Jun 16 - Jun 17
Total with taxes and fees
A private beach, 2 restaurants, and 2 outdoor pools are all featured at this resort. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
8.6/10 Excellent! (1,071 reviews)
"Always have a great time when I stay in Baker’s Cay! I love the private beach on the property and the food is delicious! You don’t need to leave the property to have a good time."
Reviewed on May 18, 2026
Amara Cay Resort
80001 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$254 nightly
The price is $286 total per night from May 28 to May 29
$286 total
May 28 - May 29
Total with taxes and fees
A private beach, 2 restaurants, and an outdoor pool are all featured at this resort. If you want to take your pet along, this pet-friendly property offers everything ...
8.8/10 Excellent! (1,278 reviews)
"Absolutely loved this resort! Amazing service and Happy Hour at the Pool! Excellent Transportation options and within walking distance to some really nice restaurants. Great stay after 3 nights in Key West for our Anniversary. Hotel staff communicated with us to plan our arrival and was able to accommodate ..."
Reviewed on May 20, 2026
Islander Resort
82100 Overseas Highway Islamorada FL
Fully refundableReserve now, pay when you stay
$290 nightly
The price is $326 total per night from Jun 16 to Jun 17
$326 total
Jun 16 - Jun 17
Total with taxes and fees
A private beach, 3 restaurants, and 2 outdoor pools are all featured at this hotel. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Families ...
9.2/10 Wonderful! (1,017 reviews)
"Was not worth the 1200 per night we spent!"
Reviewed on May 19, 2026
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
84001 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$319 nightly
The price is $359 total per night from Jun 1 to Jun 2
$359 total
Jun 1 - Jun 2
Total with taxes and fees
This Art Deco resort features a private beach, a marina, and 4 restaurants. Enjoy a day at the beach snorkeling, or relax with sun loungers. Families will appreciate ...
9/10 Wonderful! (198 reviews)
"My only suggestion is to clean the garbage littered in the beach-lounging area. There’s also litter in the ocean (under Little Limon deck) that we picked up and a strong smell of sewage that hits the nostrils as soon as we exit our room or walk towards the Tiki bar. The ice cream place also needs ..."
Reviewed on May 16, 2026
Playa Largo Resort & Spa, Autograph Collection
97450 Overseas Highway Key Largo FL
Fully refundableReserve now, pay when you stay
$392 nightly
The price is $441 total per night from Jun 2 to Jun 3
$441 total
Jun 2 - Jun 3
Total with taxes and fees
This luxury resort features a full-service spa, a marina, and 3 restaurants. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Enjoy the ...
8.8/10 Excellent! (1,001 reviews)
"The staff here is outstanding. They are professional and will go out of their way to accommodate the guest. The resort is amazing and provides a lot of events throughout the days. We will definitely be returning."
Reviewed on May 13, 2026
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
1996 Overseas Highway Marathon FL
Fully refundableReserve now, pay when you stay
$220 nightly
The price is $247 total per night from Jun 10 to Jun 11
$247 total
Jun 10 - Jun 11
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 4 restaurants. Traveling on business? Take advantage of the 3 conference rooms, along with ...
8.6/10 Excellent! (1,161 reviews)
"Rooms and property are lovely. Very clean. Love their little market and the"
Reviewed on May 18, 2026
La Siesta Resort & Villas
80241 Overseas Highway Islamorada FL
Fully refundableReserve now, pay when you stay
$230 nightly
The price is $259 total per night from May 27 to May 28
$259 total
May 27 - May 28
Total with taxes and fees
The private beach and marina are among the highlights at this resort. Enjoy the outdoor pool and perks like a free area shuttle. There's a poolside bar on site, ...
8.6/10 Excellent! (1,000 reviews)
"La Siesta has so much potential. Beautiful grounds, spacious rooms, pool and views. The front counter staff and bike staff were very nice. Unfortunately they don’t clean up the trash around the compound. To either side of our entrance was trash that had been there before us and Is probably still ..."
Reviewed on May 17, 2026
Tranquility Bay Beachfront Hotel and Resort
2600 Overseas Hwy Marathon FL
Fully refundableReserve now, pay when you stay
$329 nightly
The price is $370 total per night from Jun 14 to Jun 15
$370 total
Jun 14 - Jun 15
Total with taxes and fees
This smoke-free hotel features a private beach, 3 outdoor pools, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy ...
8.8/10 Excellent! (1,001 reviews)
"Me encanta ese hotel super tranquilo y especial"
Reviewed on May 18, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
4 Star Hotels Florida Keys
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Florida Keys 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Florida Keys will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Florida Keys, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Florida Keys hotel reviews by fellow wanderers
Waterside Suites & Marina
5 out of 5
Posted 7 hours ago
Travelocity Verified Review
"Clean apartment; bigger than expected "
A verified traveler stayed at Waterside Suites & Marina
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