Explore top 2026 4 Star Hotels in Florida Keys
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Top Florida Keys 4 Star hotels
Reefhouse Resort & Marina
103800 Overseas Hwy Key Largo FL
Fully refundableReserve now, pay when you stay
$339 nightly
The price is $376 total per night from Apr 23 to Apr 24
$376 total
Apr 23 - Apr 24
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Family-friendly ...
9.2/10 Wonderful! (1,409 reviews)
Beautiful hotel and pool. Saturday was packed with kids at pool and running through courtyard. Security calmly addressed jumping into pool full of people but parents were absent. Staff very nice and sunset anazing. Restaurant and Breezes lounge very nice
Reviewed on Apr 19, 2026
Baker's Cay Resort Key Largo, Curio Collection by Hilton
97000 Overseas Hwy Key Largo FL
$401 nightly
The price is $451 total per night from Apr 28 to Apr 29
$451 total
Apr 28 - Apr 29
Total with taxes and fees
A private beach, 2 restaurants, and 2 outdoor pools are all featured at this resort. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
8.6/10 Excellent! (1,047 reviews)
We had an ocean facing room in the Coconut Wing, and the view was absolutely STUNNING. The room was sparkling clean, nice bathroom with great water pressure in the shower. The resort definitely caters more towards families and the bar and restaurant close very early. So if you are a traveling as ...
Reviewed on Apr 21, 2026
Amara Cay Resort
80001 Overseas Hwy Islamorada FL
$338 nightly
The price is $380 total per night from Apr 30 to May 1
$380 total
Apr 30 - May 1
Total with taxes and fees
A private beach, 2 restaurants, and an outdoor pool are all featured at this resort. If you want to take your pet along, this pet-friendly property offers everything ...
8.8/10 Excellent! (1,269 reviews)
Poolside area was very comfortable. Restaurant was very friendly and helpful. The bed was very comfortable.
Reviewed on Apr 21, 2026
Hawks Cay Resort
61 Hawks Cay Blvd Marathon FL
Fully refundableReserve now, pay when you stay
$368 nightly
The price is $413 total per night from May 17 to May 18
$413 total
May 17 - May 18
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...
8/10 Very Good! (1,009 reviews)
We had a very good stay at the Hawks Cay villa we stayed in. The main pool, lagoon, Sunset Village pool, and fitness center were great. Our first night there, we stopped in Angler & Ale after a long day of travel. The service was SLOW and the food was likely bland Sysco basic options; nothing special. ...
Reviewed on Apr 20, 2026
Islander Resort
82100 Overseas Highway Islamorada FL
$270 nightly
The price is $304 total per night from May 17 to May 18
$304 total
May 17 - May 18
Total with taxes and fees
A private beach, 3 restaurants, and 2 outdoor pools are all featured at this hotel. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Families ...
9.2/10 Wonderful! (1,007 reviews)
The room was amazing. The view and back patio from the room is stunning - and you can walk right out to the beach! The room was clean and had high ceilings and was very well thought out. The bar closes at 10:45pm, so be prepared for that.
Reviewed on Apr 21, 2026
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
1996 Overseas Highway Marathon FL
Fully refundableReserve now, pay when you stay
$279 nightly
The price is $313 total per night from May 3 to May 4
$313 total
May 3 - May 4
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 4 restaurants. Traveling on business? Take advantage of the 3 conference rooms, along with ...
8.8/10 Excellent! (1,165 reviews)
Beds were not comfortable at all. Not enough pillows. Many of the staff didn't speak good English. Spa was closed cause they dont have anyone to work there. Restaurant was good with great service.
Reviewed on Apr 21, 2026
Playa Largo Resort & Spa, Autograph Collection
97450 Overseas Highway Key Largo FL
Fully refundableReserve now, pay when you stay
$408 nightly
The price is $459 total per night from May 5 to May 6
$459 total
May 5 - May 6
Total with taxes and fees
This luxury resort features a full-service spa, a marina, and 3 restaurants. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Enjoy the ...
8.8/10 Excellent! (1,001 reviews)
The restaurants were great and room was clean. The staff was very attentive and nice. Our room was on the first floor and our room was really cold so that was the only downfall. We really enjoyed our stay! Beautiful water!!
Reviewed on Apr 16, 2026
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
84001 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$313 nightly
The price is $352 total per night from May 4 to May 5
$352 total
May 4 - May 5
Total with taxes and fees
This Art Deco resort features a private beach, a marina, and 4 restaurants. Enjoy a day at the beach snorkeling, or relax with sun loungers. Families will appreciate ...
9/10 Wonderful! (187 reviews)
They hit you with a $65 per day resort fee…. Not the end of the world but not a good surprise after you leave.
Reviewed on Apr 21, 2026
La Siesta Resort & Villas
80241 Overseas Highway Islamorada FL
$268 nightly
The price is $302 total per night from Apr 30 to May 1
$302 total
Apr 30 - May 1
Total with taxes and fees
The private beach and marina are among the highlights at this resort. Enjoy the outdoor pool and perks like a free area shuttle. There's a poolside bar on site, ...
8.6/10 Excellent! (1,000 reviews)
It was simply stunning. Beautiful location, great facilities, spacious apartment and for a family of 5 the door key card being on the wristband is genius. Thank you for a wonderful stay
Reviewed on Apr 21, 2026
Tranquility Bay Beachfront Hotel and Resort
2600 Overseas Hwy Marathon FL
Fully refundableReserve now, pay when you stay
$377 nightly
The price is $425 total per night from May 13 to May 14
$425 total
May 13 - May 14
Total with taxes and fees
This smoke-free hotel features a private beach, 3 outdoor pools, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy ...
8.8/10 Excellent! (1,000 reviews)
Prepare for expensive meals and drinks.
Reviewed on Apr 3, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
4 Star Hotels Florida Keys
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Florida Keys 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Florida Keys will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Florida Keys, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Florida Keys hotel reviews by fellow wanderers
Chesapeake Beach Resort
5 out of 5
Posted 8 hours ago
Travelocity Verified Review
"Beautiful facility.
Great breakfast"
A verified traveler stayed at Chesapeake Beach Resort
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