Explore top 2026 4 Star Hotels in Florida Keys

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Top Florida Keys 4 Star hotels

Hawks Cay Resort

Hawks Cay Resort

4 out of 5
61 Hawks Cay Blvd Marathon FL
Fully refundableReserve now, pay when you stay
$538 nightly
The price is $604 total per night from Mar 1 to Mar 2
$604 total
Mar 1 - Mar 2
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...
8/10 Very Good! (1,007 reviews)
Great

Reviewed on Feb 15, 2026

Opens in a new windowHawks Cay Resort
Amara Cay Resort

Amara Cay Resort

4 out of 5
80001 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$423 nightly
The price is $476 total per night from Feb 25 to Feb 26
$476 total
Feb 25 - Feb 26
Total with taxes and fees
A private beach, 2 restaurants, and an outdoor pool are all featured at this resort. If you want to take your pet along, this pet-friendly property offers everything ...
8.8/10 Excellent! (1,254 reviews)
Room was clean. Daily care was timely and immaculate. Staff was incredible. The atmosphere was delightful. We had such an amazing time.

Reviewed on Feb 15, 2026

Opens in a new windowAmara Cay Resort
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

4 out of 5
97000 Overseas Hwy Key Largo FL
Fully refundableReserve now, pay when you stay
$582 nightly
The price is $655 total per night from Mar 5 to Mar 6
$655 total
Mar 5 - Mar 6
Total with taxes and fees
A private beach, 2 restaurants, and 2 outdoor pools are all featured at this resort. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
8.4/10 Very Good! (1,000 reviews)
Beautiful property. Staff was accommodating. Quiet in the room. Dry Rocks was great. Not impressed by Calusa.

Reviewed on Feb 10, 2026

Opens in a new windowBaker's Cay Resort Key Largo, Curio Collection by Hilton
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

4.5 out of 5
97450 Overseas Highway Key Largo FL
Fully refundableReserve now, pay when you stay
$548 nightly
The price is $617 total per night from Feb 17 to Feb 18
$617 total
Feb 17 - Feb 18
Total with taxes and fees
This luxury resort features a full-service spa, a marina, and 3 restaurants. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Enjoy the ...
8.8/10 Excellent! (1,003 reviews)
Great stay. Professional and insightful staff. Will be visiting again in the future!

Reviewed on Feb 12, 2026

Opens in a new windowPlaya Largo Resort & Spa, Autograph Collection
Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

4 out of 5
1996 Overseas Highway Marathon FL
Fully refundableReserve now, pay when you stay
$344 nightly
The price is $387 total per night from Mar 1 to Mar 2
$387 total
Mar 1 - Mar 2
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 4 restaurants. Enjoy a day at the beach kayaking, or relax with sun loungers. Enjoy the 4 outdoor ...
8.6/10 Excellent! (1,227 reviews)
YES & YES— clean room, amenities & well kept property. Staff, especially Otis. More should be done to redirect, reorient unfamiliar guests from the front desk at number 1996 near the public street to the back of the property where check in and registration occurs.

Reviewed on Feb 8, 2026

Opens in a new windowFaro Blanco Resort & Yacht Club Marathon, Curio by Hilton
Islander Resort

Islander Resort

4 out of 5
82100 Overseas Highway Islamorada FL
Fully refundableReserve now, pay when you stay
$434 nightly
The price is $488 total per night from Mar 2 to Mar 3
$488 total
Mar 2 - Mar 3
Total with taxes and fees
A private beach, 3 restaurants, and 2 outdoor pools are all featured at this hotel. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Families ...
9.2/10 Wonderful! (1,000 reviews)
Nice size room, beautiful grounds

Reviewed on Feb 10, 2026

Opens in a new windowIslander Resort
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

4 out of 5
2600 Overseas Hwy Marathon FL
Fully refundableReserve now, pay when you stay
$559 nightly
The price is $629 total per night from Feb 23 to Feb 24
$629 total
Feb 23 - Feb 24
Total with taxes and fees
This smoke-free hotel features a private beach, 3 outdoor pools, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy ...
8.8/10 Excellent! (1,001 reviews)
We loved the hotel overall with a few issues to note. Staff was extremely friendly and helpful whenever needed. All of the staff at outside tiki bar/restaurant were absolutely great. Food was excellent and entertainment was great. Pool near beach was great, clean and well kept. Few hiccups: One day ...

Reviewed on Feb 5, 2026

Opens in a new windowTranquility Bay Beachfront Hotel and Resort
La Siesta Resort & Villas

La Siesta Resort & Villas

4 out of 5
80241 Overseas Highway Islamorada FL
$432 nightly
The price is $487 total per night from Mar 1 to Mar 2
$487 total
Mar 1 - Mar 2
Total with taxes and fees
The private beach and marina are among the highlights at this resort. Enjoy the outdoor pool and perks like a free area shuttle. There's a poolside bar on site, ...
8.6/10 Excellent! (1,003 reviews)
Yes

Reviewed on Feb 12, 2026

Opens in a new windowLa Siesta Resort & Villas
Villas At Hawks Cay Resort

Villas At Hawks Cay Resort

4 out of 5
61 Hawks Cay Boulevard Marathon FL
This luxury resort features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...
8.2/10 Very Good! (163 reviews)
Very nice villa, loved the location. Clean and well maintained. We felt a little neglected by the staff however. Asked for trash pickup and never received it. Also towels.

Reviewed on Feb 11, 2026

Opens in a new windowVillas At Hawks Cay Resort
The Islands of Islamorada

The Islands of Islamorada

4 out of 5
82779 Old Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$948 nightly
The price is $1,067 total per night from Feb 26 to Feb 27
$1,067 total
Feb 26 - Feb 27
Total with taxes and fees
2 outdoor pools, a 24-hour gym, and a hot tub are all featured at this smoke-free villa. Spend a day at the beach kayaking, or relax with sun loungers and beach ...
9.6/10 Exceptional! (70 reviews)
Beautiful accommodations and location, very clean, many activities available at resort

Reviewed on Nov 25, 2025

Opens in a new windowThe Islands of Islamorada
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4 Star Hotels Florida Keys

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Florida Keys 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Florida Keys will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Florida Keys, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Florida Keys hotel reviews by fellow wanderers