Explore top 2026 4 Star Hotels in Florida Keys

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Top Florida Keys 4 Star hotels

Hawks Cay Resort

Hawks Cay Resort

4 out of 5
61 Hawks Cay Blvd Marathon FL
Fully refundableReserve now, pay when you stay
$385 nightly
The price is $432 total per night from Dec 15 to Dec 16
$432 total
Dec 15 - Dec 16
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...
8/10 Very Good! (1,009 reviews)
Rooms were clean

Reviewed on Dec 1, 2025

Opens in a new windowHawks Cay Resort
Amara Cay Resort

Amara Cay Resort

4 out of 5
80001 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$250 nightly
The price is $282 total per night from Dec 15 to Dec 16
$282 total
Dec 15 - Dec 16
Total with taxes and fees
A private beach and a restaurant are featured at this resort. If you want to take your pet along, this pet-friendly property offers everything you'll need for ...
8.8/10 Excellent! (1,255 reviews)
Great location right on the ocean

Reviewed on Dec 5, 2025

Opens in a new windowAmara Cay Resort
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

4 out of 5
97000 Overseas Hwy Key Largo FL
$302 nightly
The price is $340 total per night from Dec 15 to Dec 16
$340 total
Dec 15 - Dec 16
Total with taxes and fees
A private beach, 2 restaurants, and 2 outdoor pools are all featured at this resort. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
8.6/10 Excellent! (1,004 reviews)
Anniversary trip. King Waterview room in the Coconut Wing. Highest compliments to the staff, who were friendly, accommodating, greeted you all day long and worked hard at several different positions throughout the day. The resort and rooms have a bit of wear and tear. The room was clean, but not ...

Reviewed on Dec 6, 2025

Opens in a new windowBaker's Cay Resort Key Largo, Curio Collection by Hilton
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

4.5 out of 5
97450 Overseas Highway Key Largo FL
Fully refundableReserve now, pay when you stay
$312 nightly
The price is $351 total per night from Dec 15 to Dec 16
$351 total
Dec 15 - Dec 16
Total with taxes and fees
This luxury resort features a full-service spa, a marina, and 3 restaurants. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Enjoy the ...
8.8/10 Excellent! (1,000 reviews)
This resort has it all. I will go back.

Reviewed on Nov 18, 2025

Opens in a new windowPlaya Largo Resort & Spa, Autograph Collection
Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

4 out of 5
1996 Overseas Highway Marathon FL
$197 nightly
The price is $221 total per night from Dec 15 to Dec 16
$221 total
Dec 15 - Dec 16
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 4 restaurants. Enjoy a day at the beach kayaking, or relax with sun loungers. Enjoy the 4 outdoor ...
8.8/10 Excellent! (1,276 reviews)
Very good property

Reviewed on Nov 30, 2025

Opens in a new windowFaro Blanco Resort & Yacht Club Marathon, Curio by Hilton
Islander Resort

Islander Resort

4 out of 5
82100 Overseas Highway Islamorada FL
Fully refundableReserve now, pay when you stay
$301 nightly
The price is $339 total per night from Dec 18 to Dec 19
$339 total
Dec 18 - Dec 19
Total with taxes and fees
A private beach, 3 restaurants, and 2 outdoor pools are all featured at this hotel. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Families ...
9.2/10 Wonderful! (1,002 reviews)
This resort was just what we needed. It started out with a small hicup, we checked in late and they gave our king bed room away. Front desk said something like Expedia oversells their property and there was nothing left that she could do. We had to take the double room. After a while my husband went ...

Reviewed on Dec 8, 2025

Opens in a new windowIslander Resort
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

4 out of 5
2600 Overseas Hwy Marathon FL
Fully refundableReserve now, pay when you stay
$245 nightly
The price is $276 total per night from Dec 10 to Dec 11
$276 total
Dec 10 - Dec 11
Total with taxes and fees
This smoke-free hotel features a private beach, 3 outdoor pools, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy ...
8.8/10 Excellent! (1,000 reviews)
The place was great and appropriately named because it was very tranquil and relaxing. The only disappointment was that there is no spa facility and breakfast available only in your room.

Reviewed on Nov 27, 2025

Opens in a new windowTranquility Bay Beachfront Hotel and Resort
La Siesta Resort & Villas

La Siesta Resort & Villas

4 out of 5
80241 Overseas Highway Islamorada FL
Fully refundableReserve now, pay when you stay
$246 nightly
The price is $276 total per night from Dec 14 to Dec 15
$276 total
Dec 14 - Dec 15
Total with taxes and fees
The private beach and marina are among the highlights at this resort. Enjoy the outdoor pool and perks like a free area shuttle. There's a poolside bar on site, ...
8.6/10 Excellent! (1,001 reviews)
Great stay and beautiful space

Reviewed on Dec 1, 2025

Opens in a new windowLa Siesta Resort & Villas
Villas At Hawks Cay Resort

Villas At Hawks Cay Resort

4 out of 5
61 Hawks Cay Boulevard Marathon FL
This luxury resort features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...
8.4/10 Very Good! (147 reviews)
great trip. Clean, easy to get around. Good amenities for a family trip.

Reviewed on Nov 16, 2025

Opens in a new windowVillas At Hawks Cay Resort
The Islands of Islamorada

The Islands of Islamorada

4 out of 5
82779 Old Hwy Islamorada FL
$648 nightly
The price is $729 total per night from Dec 15 to Dec 16
$729 total
Dec 15 - Dec 16
Total with taxes and fees
2 outdoor pools, a 24-hour gym, and a hot tub are all featured at this smoke-free villa. Spend a day at the beach kayaking, or relax with sun loungers and beach ...
9.6/10 Exceptional! (69 reviews)
Beautiful accommodations and location, very clean, many activities available at resort

Reviewed on Nov 25, 2025

Opens in a new windowThe Islands of Islamorada
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4 Star Hotels Florida Keys

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Florida Keys 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Florida Keys will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Florida Keys, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Florida Keys hotel reviews by fellow wanderers