Explore top 2026 4 Star Hotels in Florida Keys
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Top Florida Keys 4 Star hotels
Hawks Cay Resort
61 Hawks Cay Blvd Marathon FL
Fully refundableReserve now, pay when you stay
$255 nightly
The price is $286 total per night from Sep 13 to Sep 14
$286 total
Sep 13 - Sep 14
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...
8.2/10 Very Good! (1,006 reviews)
"Great place. Loved the area, the staff very helpful and nice. The villa could used a better cleaning but overall was a great stay, will definitely be back!!!"
Reviewed on Aug 31, 2026
Baker's Cay Resort Key Largo, Curio Collection by Hilton
97000 Overseas Hwy Key Largo FL
$286 nightly
The price is $322 total per night from Sep 28 to Sep 29
$322 total
Sep 28 - Sep 29
Total with taxes and fees
A private beach, 2 restaurants, and 2 outdoor pools are all featured at this resort. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
8.6/10 Excellent! (1,176 reviews)
"To begin with, when we arrived, the person who assisted us did not give us a proper welcome or make us feel welcomed at the hotel. She did not provide us with any recommendations whatsoever, nor did she even show us where our room was located. We saw how the guests who were assisted before us were ..."
Reviewed on Sep 1, 2026
Amara Cay Resort
80001 Overseas Hwy Islamorada FL
$211 nightly
The price is $237 total per night from Sep 23 to Sep 24
$237 total
Sep 23 - Sep 24
Total with taxes and fees
A private beach, 2 restaurants, and an outdoor pool are all featured at this resort. If you want to take your pet along, this pet-friendly property offers everything ...
8.8/10 Excellent! (1,305 reviews)
"Wonderful resort, very friendly staff, would definitely stay again!"
Reviewed on Sep 1, 2026
Reefhouse Resort & Marina
103800 Overseas Hwy Key Largo FL
Fully refundableReserve now, pay when you stay
$259 nightly
The price is $286 total per night from Sep 2 to Sep 3
$286 total
Sep 2 - Sep 3
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Family-friendly ...
Islander Resort
82100 Overseas Highway Islamorada FL
Fully refundableReserve now, pay when you stay
$287 nightly
The price is $323 total per night from Sep 22 to Sep 23
$323 total
Sep 22 - Sep 23
Total with taxes and fees
A private beach, 3 restaurants, and 2 outdoor pools are all featured at this hotel. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Families ...
9.4/10 Exceptional! (1,112 reviews)
"Great property with an amazing concept, especially in an area where there aren’t many high-end properties offering this style and experience. The facilities are excellent, and overall we really enjoyed our stay. My only negative feedback is that a few members of staff were constantly on their phones ..."
Reviewed on Aug 31, 2026
Playa Largo Resort & Spa, Autograph Collection
97450 Overseas Highway Key Largo FL
Fully refundableReserve now, pay when you stay
$304 nightly
The price is $342 total per night from Sep 14 to Sep 15
$342 total
Sep 14 - Sep 15
Total with taxes and fees
This luxury resort features a full-service spa, a marina, and 3 restaurants. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Enjoy the ...
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
84001 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$240 nightly
The price is $270 total per night from Sep 7 to Sep 8
$270 total
Sep 7 - Sep 8
Total with taxes and fees
This Art Deco resort features a private beach, a marina, and 4 restaurants. Enjoy a day at the beach snorkeling, or relax with sun loungers. Families will appreciate ...
9/10 Wonderful! (258 reviews)
"we loved it !!!"
Reviewed on Aug 31, 2026
Tranquility Bay Beachfront Hotel and Resort
2600 Overseas Hwy Marathon FL
Fully refundableReserve now, pay when you stay
$248 nightly
The price is $279 total per night from Sep 21 to Sep 22
$279 total
Sep 21 - Sep 22
Total with taxes and fees
This smoke-free hotel features a private beach, 3 outdoor pools, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy ...
8.8/10 Excellent! (1,009 reviews)
"This is a beautiful place to stay! Very well kept"
Reviewed on Sep 1, 2026
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
1996 Overseas Highway Marathon FL
Fully refundableReserve now, pay when you stay
$180 nightly
The price is $203 total per night from Sep 7 to Sep 8
$203 total
Sep 7 - Sep 8
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 4 restaurants. Traveling on business? Take advantage of the 3 conference rooms, along with ...
La Siesta Resort & Villas
80241 Overseas Highway Islamorada FL
$229 nightly
The price is $258 total per night from Sep 3 to Sep 4
$258 total
Sep 3 - Sep 4
Total with taxes and fees
The private beach and marina are among the highlights at this resort. Enjoy the outdoor pool and perks like a free area shuttle. There's a poolside bar on site, ...
8.8/10 Excellent! (1,005 reviews)
"Good"
Reviewed on Aug 30, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
4 Star Hotels Florida Keys
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Florida Keys 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Florida Keys will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Florida Keys, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Florida Keys hotel reviews by fellow wanderers
Amara Cay Resort
5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"Wonderful resort, very friendly staff, would definitely stay again!"
A verified traveler stayed at Amara Cay Resort
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