Explore top 2026 4 Star Hotels in Florida Keys
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Top Florida Keys 4 Star hotels
Reefhouse Resort & Marina
103800 Overseas Hwy Key Largo FL
Fully refundableReserve now, pay when you stay
$239 nightly
The price is $264 total per night from Jun 7 to Jun 8
$264 total
Jun 7 - Jun 8
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Family-friendly ...
9.4/10 Exceptional! (1,465 reviews)
"Awesome stay!"
Reviewed on Jun 3, 2026
Hawks Cay Resort
61 Hawks Cay Blvd Marathon FL
Fully refundableReserve now, pay when you stay
$292 nightly
The price is $327 total per night from Jun 29 to Jun 30
$327 total
Jun 29 - Jun 30
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...
8.2/10 Very Good! (1,010 reviews)
"This is really neat and a unique find. The dinner at salt and ash we had was amazing! We were upgraded to a villa and it was decent but the downstairs bathroom was locked and it needed some better cleaning in the bathrooms upstairs and towel racks!!! It wasn’t horrible, but not the best…. I didn’t ..."
Reviewed on Jun 3, 2026
Baker's Cay Resort Key Largo, Curio Collection by Hilton
97000 Overseas Hwy Key Largo FL
$302 nightly
The price is $340 total per night from Jun 16 to Jun 17
$340 total
Jun 16 - Jun 17
Total with taxes and fees
A private beach, 2 restaurants, and 2 outdoor pools are all featured at this resort. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
8.6/10 Excellent! (1,073 reviews)
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Reviewed on Jun 1, 2026
Amara Cay Resort
80001 Overseas Hwy Islamorada FL
$256 nightly
The price is $288 total per night from Jun 17 to Jun 18
$288 total
Jun 17 - Jun 18
Total with taxes and fees
A private beach, 2 restaurants, and an outdoor pool are all featured at this resort. If you want to take your pet along, this pet-friendly property offers everything ...
8.8/10 Excellent! (1,289 reviews)
"Muy buen plan en familia para ir a los cayos. Buena atención y limpieza"
Reviewed on Jun 1, 2026
Islander Resort
82100 Overseas Highway Islamorada FL
Fully refundableReserve now, pay when you stay
$283 nightly
The price is $318 total per night from Jun 23 to Jun 24
$318 total
Jun 23 - Jun 24
Total with taxes and fees
A private beach, 3 restaurants, and 2 outdoor pools are all featured at this hotel. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Families ...
9.4/10 Exceptional! (1,030 reviews)
"Would definitely stay there, again!"
Reviewed on Jun 3, 2026
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
84001 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$345 nightly
The price is $388 total per night from Jun 21 to Jun 22
$388 total
Jun 21 - Jun 22
Total with taxes and fees
This Art Deco resort features a private beach, a marina, and 4 restaurants. Enjoy a day at the beach snorkeling, or relax with sun loungers. Families will appreciate ...
9/10 Wonderful! (202 reviews)
"The property was beautiful as soon as we pulled up we were greeted by a woman on a golf cart. She was so happy and helpful. It made us feel comfortable right away, showed us to the front desk and she was also so very friendly. I wish I remembered their names. We got an ocean view. It also overlooked ..."
Reviewed on May 30, 2026
Playa Largo Resort & Spa, Autograph Collection
97450 Overseas Highway Key Largo FL
Fully refundableReserve now, pay when you stay
$344 nightly
The price is $387 total per night from Jun 16 to Jun 17
$387 total
Jun 16 - Jun 17
Total with taxes and fees
This luxury resort features a full-service spa, a marina, and 3 restaurants. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Enjoy the ...
9/10 Wonderful! (1,001 reviews)
"The place was spectacular. Beach bartenders were great. Definitely will Be back"
Reviewed on May 31, 2026
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
1996 Overseas Highway Marathon FL
Fully refundableReserve now, pay when you stay
$196 nightly
The price is $221 total per night from Jun 8 to Jun 9
$221 total
Jun 8 - Jun 9
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 4 restaurants. Traveling on business? Take advantage of the 3 conference rooms, along with ...
8.6/10 Excellent! (1,161 reviews)
"The hot tub was not on the property but was accessible through the property next-door, which was a little bit of a walk. Would have given it five stars if it wasn’t for the terrible individual at check-in. I don’t remember his name, but he stayed in the room in the back, not in the front where he ..."
Reviewed on Jun 1, 2026
La Siesta Resort & Villas
80241 Overseas Highway Islamorada FL
$253 nightly
The price is $284 total per night from Jun 14 to Jun 15
$284 total
Jun 14 - Jun 15
Total with taxes and fees
The private beach and marina are among the highlights at this resort. Enjoy the outdoor pool and perks like a free area shuttle. There's a poolside bar on site, ...
8.6/10 Excellent! (1,005 reviews)
"Fantastic property. Quiet and family friendly."
Reviewed on Jun 2, 2026
Tranquility Bay Beachfront Hotel and Resort
2600 Overseas Hwy Marathon FL
Fully refundableReserve now, pay when you stay
$297 nightly
The price is $334 total per night from Jun 28 to Jun 29
$334 total
Jun 28 - Jun 29
Total with taxes and fees
This smoke-free hotel features a private beach, 3 outdoor pools, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy ...
8.8/10 Excellent! (1,000 reviews)
"Me encantó todo, sin duda volveria"
Reviewed on Jun 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
4 Star Hotels Florida Keys
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Florida Keys 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Florida Keys will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Florida Keys, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Florida Keys hotel reviews by fellow wanderers
Islander Resort
5 out of 5
Posted 8 hours ago
Travelocity Verified Review
"Would definitely stay there, again!"
A verified traveler stayed at Islander Resort
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