Cheap Flights to Cusco Region from $50 (2025/2026)

Feel at ease with free flight cancellations within 24 hours of booking

Change your flight without a fee on select flights

Jet to one of Cusco Region's top cities

How Much Does it Cost To Fly To Cusco Region?

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

OriginDestinationTravel DatesFlights From*
LIMCuscoJanuary 17 to January 19$92
SCLCuscoMarch 8 to March 15$263
MIACuscoJanuary 23 to January 25$409
LPBCuscoMarch 4 to March 8$424
GIGCuscoJanuary 18 to February 2$534
MEXCuscoDecember 8 to December 12$613
ORDCuscoFebruary 1 to February 8$690
LAXCuscoJanuary 26 to February 2$691
SFOCuscoJanuary 27 to February 3$758
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
LIMCuscoNovember 29 to December 7$95
MIACuscoNovember 30 to December 7$578
ORDCuscoNovember 29 to December 6$733
MEXCuscoNovember 30 to December 13$752
LAXCuscoNovember 30 to December 5$915
SFOCuscoNovember 28 to December 11$969
*Prices include taxes and fees

Best Cusco Region Flight and Hotel Packages

Price found within the past 48 hours. Click for updated prices.
Avraham Holtels
Sumaq Machu Picchu Hotel
Jaya Machupicchu Boutique Hotel
Don't see what you're looking for?
See all available trips from Houston to Cusco Region
View all trips

Travelers ❤️ These Cusco Region 🏨

Wyndham Costa del Sol Cusco

Wyndham Costa del Sol Cusco

4 out of 5
Santa Teresa N 344 Cusco Cusco
Book a stay at this business-friendly hotel in Cusco. Enjoy free breakfast, free WiFi, and 24-hour room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Plaza de Armas and Museo de Plantas Sagradas Magicas y Medicinales are located nearby.
9.4/10 Exceptional! (1,094 reviews)
Everything exceeded expectations

Reviewed on Nov 21, 2025

Opens in a new windowWyndham Costa del Sol Cusco
Palacio del Inka, A Luxury Collection Hotel by Marriott

Palacio del Inka, A Luxury Collection Hotel by Marriott

5 out of 5
Plazoleta Santo Domingo No 259 Cusco Cusco
Book a stay at this luxury hotel in Cusco. Enjoy a full-service spa, room service, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions Plaza de Armas and Quechua Museum are located nearby.
9.4/10 Exceptional! (960 reviews)
Very clean and safe with extremely attentive staff. Great location for restaurants and shops. I would highly recommend this hotel.

Reviewed on Nov 14, 2025

Opens in a new windowPalacio del Inka, A Luxury Collection Hotel by Marriott
JW Marriott El Convento Cusco

JW Marriott El Convento Cusco

5 out of 5
Esquina De La Calle Ruinas 432 Cusco Cusco
Book a stay at this luxury hotel in Cusco. Enjoy free breakfast, a full-service spa, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Plaza de Armas and Gato's Market are located nearby.
9.6/10 Exceptional! (1,006 reviews)
Beautiful hotel

Reviewed on Nov 15, 2025

Opens in a new windowJW Marriott El Convento Cusco
Save an average of 15% on thousands of hotels when you're signed in
Sonesta Hotel Cusco

Sonesta Hotel Cusco

4 out of 5
Ave. El Sol 954 Cusco Cusco
Stay at this hotel in Cusco. Enjoy free breakfast, free WiFi, and 2 bars/lounges. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Plaza de Armas and Orellana Pumaqchupan Park are located nearby.
9.4/10 Exceptional! (1,011 reviews)
This hotel was fantastic, everyone from the staff was really lovely and approachable. The location was great for any nearby sights and even for the train to Machu Picchu. The rooms were spacious and clean, the breakfast was delicious and also openining it from 3 am is a nice touch for all the hikers. ...

Reviewed on Nov 21, 2025

Opens in a new windowSonesta Hotel Cusco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Explore More Ways to Travel with Travelocity