Deals on vacations and trips to Santiago

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Santiago flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
Radisson Riviera Panama

Radisson Riviera Panama

4 out of 5
Price was $944, price is now $700 per person
$700
per person
May 29 - Jun 4
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
A full-service spa, 2 restaurants, and 2 outdoor pools are all featured at this Art Deco hotel. Relax with a drink at one of the 2 bars/lounges and enjoy free perks like buffet breakfast and free self parking. A poolside bar, a 24-hour front desk, and a coffee shop are also provided.
Mahogany Suites

Mahogany Suites

2 out of 5
Price was $1,495, price is now $820 per person
$820
per person
May 14 - May 21
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
A golf course and an outdoor pool are featured at this hotel. A garden is also provided.
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Price was $1,108, price is now $714 per person
$714
per person
May 3 - May 9
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
This bed & breakfast features an outdoor pool and a bar/lounge. Guests will appreciate free perks like free self parking and WiFi in public areas. An area shuttle, a casino shuttle, and laundry facilities are also offered.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $2,200, price is now $1,461 per person
$1,461
per person
Jun 1 - Jun 8
found 14 hours ago
Roundtrip non-stop flight included
Dallas (DFW) to Panama City (PTY)
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.
Hotel Plaza Herrera

Hotel Plaza Herrera

4 out of 5
Casco Viejo
Price was $1,635, price is now $1,109 per person
$1,109
per person
May 7 - May 11
found 6 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
An attached winery and a restaurant are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and airport shuttle. Valet parking, a coffee shop, and a snack bar/deli are also offered.

Top Santiago hotels deals

Hotel Gran David

Hotel Gran David

3.5 out of 5
Vía Interamericana Santiago Veraguas
Free Cancellation
Reserve now, pay when you stay
$67 nightly
The price is $75 total per night
$75 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and onsite conference space. Enjoy the 24-hour gym and free perks like cooked-to-order breakfast and free self parking.
Pool
Breakfast included
Minutes from downtown Santiago, Chicho Fábrega hospital and Universidad Latina.

Minutes from downtown Santiago, Chicho Fábrega hospital and Universidad Latina.

Panama Panamá
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This vacation home includes a garden and laundry facilities.
Kitchen
Washer
HOTEL PLAZA COROTÚ

HOTEL PLAZA COROTÚ

2 out of 5
Carr. Panamericana Santiago Provincia de Veraguas
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Free WiFi in public areas is provided and the front desk is staffed around-the-clock. Laundry facilities are provided for your convenience.
Pet friendly
Free WiFi
The Spring Loft | Santiago

The Spring Loft | Santiago

Santiago Provincia de Veraguas
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A garden is available at this apartment.
Pet friendly
Free WiFi
Hostal Travelers

Hostal Travelers

2 out of 5
Santiago de Veraguas Santiago Veraguas
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This hostal doesn't skimp on freebies - guests receive free WiFi and free self parking. If you want to take your pet along, this pet-friendly property offers everything you'll need for your pet including food and water bowls. A terrace, a garden, and a snack bar/deli are also on offer.
Pet friendly
Parking included
Hotel Mykonos Panama

Hotel Mykonos Panama

3.5 out of 5
Panamerican Highway Nuevo Santiago Veraguas
Free Cancellation
Reserve now, pay when you stay
$73 nightly
The price is $82 total per night
$82 total
Apr 13 - Apr 14
Total with taxes and fees
This smoke-free hotel features a full-service spa, 3 outdoor pools, and a restaurant. There's fun for all ages with a children's pool and a playground, and families will appreciate the onsite laundry facilities. Enjoy the gym and free perks like cooked-to-order breakfast and valet parking.
Pool
Breakfast included
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See all available properties in Santiago
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Escuela Normal Juan Demostenes Arosemena

5/5(2 reviews)

Explore the campus of Escuela Normal Juan Demostenes Arosemena, during your trip to Santiago. Stroll along the lakeside or visit the cathedral while you're in the area.

Escuela Normal Juan Demostenes Arosemena

Catedral of Santiago Apostol

Find out about the history of Santiago when you take a trip to Catedral of Santiago Apostol. Amble around the area's lakeside or visit its cathedral.

Catedral of Santiago Apostol

Plaza Banconal

5/5(1 review)

You can find the perfect gifts to bring home at Plaza Banconal during your stay in Santiago. Stroll along the lakeside or visit the cathedral while you're in the area.

Plaza Banconal

Frequently asked questions

How much are vacation packages to Santiago?
Packages, which provide both flights and hotels in Santiago, start from $700. Turn your travel fantasies into reality and book your trip with Travelocity today.
Where can I get the best vacation package deals for Santiago?
You'll come across a terrific selection of Santiago package deals on Travelocity. With as many as 400 airlines and 1,000,000 properties worldwide, crafting the ultimate escape will be a piece of cake.
Why should I purchase my Santiago vacation package with Travelocity?
Travel is all about making cherished new memories and leaving all your troubles behind — which is why we provide you with a team of experts on hand around-the-clock should you need them. On top of that, our Price Match Guarantee ensures you'll always get the best price available on our terrific range of destinations. So what are you waiting for? There's no time like the present to lock in that vacation you've always wanted.
Can I save on my Santiago car rental if I book it with a hotel or flight?
With a Santiago vacation package, you can combine your hotel, car and flight bookings and save loads. If you want to see the best of this fabulous area, why not start with Miraflores Locks? This popular sight is 110 mi from Santiago. With a rental car, you'll be there before you know it.
What is there to do in Santiago?
While getting off the beaten track can be rewarding, you really shouldn't miss the big-name sights that make a place famous. Catedral of Santiago Apostol and Omar Torrijos Herrera Stadium are a couple of them in Santiago.
Where should I stay when visiting Santiago?
The Hotel Gran David is popular with many travelers. Book now before it's too late.

Photos of local treasures

Browse Santiago vacation photos for more inspiration

UNESCO World Heritage Site Fort San Jeronimo located in Portobelo, Panama.
Adobe
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the san jeronimo fort in portobelo panama.jpg