Book Hotels in Santiago

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Santiago hotels

HOTEL VISTA LAGO

HOTEL VISTA LAGO

3 out of 5
Rincón Largo, La Pena, Santiago de Veraguas
Fully refundableReserve now, pay when you stay
The price is $84 total per night from Jul 14 to Jul 15
$84 total
per night
Jul 14 - Jul 15
This hotel features 2 bars/lounges and an outdoor pool. Enjoy a meal from the restaurant and perks like free continental breakfast and free self parking. Free ...
"Very clean, food was 10/10"

Reviewed on Jul 10, 2025

HOTEL VISTA LAGO
HOTEL PLAZA COROTÚ

HOTEL PLAZA COROTÚ

2 out of 5
Carr. Panamericana, Santiago, Provincia de Veraguas
Free WiFi in public areas is provided and the front desk is staffed around-the-clock. Laundry facilities are provided for your convenience.
"They will wash and laundry for a reasonable fee."

Reviewed on Feb 24, 2025

Get rates
HOTEL PLAZA COROTÚ
Hotel Mykonos Panama

Hotel Mykonos Panama

3.5 out of 5
Panamerican Highway, in front of Ruben Cantu Airport, Nuevo Santiago, Veraguas
Fully refundableReserve now, pay when you stay
The price is $96 total per night from Aug 12 to Aug 13
$96 total
per night
Aug 12 - Aug 13
This smoke-free hotel features a full-service spa, 3 outdoor pools, and a restaurant. There's fun for all ages with a children's pool and a playground, and families ...
"Great location and service."

Reviewed on Jun 28, 2025

Hotel Mykonos Panama
Hotel Gran David

Hotel Gran David

3.5 out of 5
Vía Interamericana, Santiago, Veraguas
Fully refundableReserve now, pay when you stay
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and onsite conference ...
"I did not like the stale smell in the room when I entered it and the smell was persistent."

Reviewed on Jun 12, 2025

Get rates
Hotel Gran David
Hotel Galería

Hotel Galería

3 out of 5
Vía Interamericana Santiago, Km 232.88, Nuevo Santiago
Fully refundableReserve now, pay when you stay
The price is $78 total per night from Jul 25 to Jul 26
$78 total
per night
Jul 25 - Jul 26
This traditional hotel features 2 outdoor pools, a gym, and a restaurant. Traveling on business? Take advantage of the 3 conference rooms, along with free WiFi ...
Perfect overnight stop
"We stayed over night on our way home from Panama City. I used the pool, very clean and refreshing. Everything was clean and comfortable. I couldn’t get hot water in the shower, but my son had no problem. The breakfast was excellent."

Reviewed on Jun 21, 2025

Hotel Galería
Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone

Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone

2 out of 5
Santiago
Stay at this vacation home in Santiago. Enjoy air conditioning. Popular attractions Parque Nacional Cerro Hoya and Cerámica La Peña are located nearby.
Get rates
Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone
Hostal Travelers

Hostal Travelers

2 out of 5
Santiago de Veraguas, Paso las Tablas, Santiago, Veraguas
This hostal doesn't skimp on freebies - guests receive free WiFi and free self parking. If you want to take your pet along, this pet-friendly property offers ...
"Kind and considerate owners. Would recommend again"

Reviewed on Jan 18, 2020

Get rates
Hostal Travelers
Cabañas Palma Real

Cabañas Palma Real

3 out of 5
Las Colomas, Santiago Sur via principal, 68035902, Santiago Sur, Provincia de Veraguas
The price is $75 total per night from Jul 13 to Jul 14
$75 total
per night
Jul 13 - Jul 14
An outdoor pool, free self parking, and barbecue grills are featured at this cabin. WiFi in public areas is free. A terrace and a garden are also provided.
Cabañas Palma Real
Hotel Plaza

Hotel Plaza

3 out of 5
Interamericana, Nuevo Santiago, Veraguas
A restaurant and an outdoor pool are featured at this hotel. There's fun for all ages with a children's club and a playground. Guests will appreciate free perks ...
"It's a 35 $ a night hotel !!"

Reviewed on Aug 21, 2023

Get rates
Hotel Plaza
Don't see what you're looking for?
See all available properties in Santiago
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santiago Hotel & Travel Guide\n

Are you intending on spending time in Panama and looking to reserve lodgings around the bright lights of Santiago? Downtown Santiago boasts 2 modern accommodation options within a 6-mile (10-kilometer) radius.

The Hotel Mykonos Panama is a great option for your stay because it is one of the most conveniently positioned Travelocity-listed rooms, one of the few options within a short walk of the Santiago downtown area.

The Hotel Mykonos Panama is located 1 mile (1.6 kilometers) from the center of Santiago. The Hotel Vista Lago Ecoresort is a mere 7 miles (12 kilometers) away.

50 miles (83 kilometers) away from Santiago, you will reach Las Tablas, where you'll find Iglesia Santa Librada and Museo Belisario Porras. The Hotel Don Jesus and Hotel Piamonte are just some examples of the convenient long and short-stay choices in Las Tablas. Or stay in Chitre, 35 miles (59 kilometers) to the east of Santiago, where you'll find the Los Guayacanes and Gran Hotel Azuero. While in Chitre, set aside a little time to check out the Catedral San Juan Bautista and Herrera Museum.

If you are flying via Marcos A. Gelabert International Airport, you might like to book Travelocity-listed accommodation at The Canal House, or American Trade Hotel, which are both conveniently close.

Frequently asked questions

What are the top kid-friendly hotels in Santiago?
Take some of the challenges out of traveling with little ones by staying in a family-friendly hotel in Santiago. From fun amenities to services that bring a smile, these properties come with perks that'll make your visit go off without a hitch: Hotel Ana Mary will help make your adventure the best one yet. It comes with a range of conveniences geared toward families, such as front desk services and housekeeping services. Alternatively, spend your Santiago break at Residencial Camino del Sol. Make the most of front desk services, housekeeping services and more here.
Where can I find cheap hotels in Santiago?
At Travelocity you'll find really nice hotels in Santiago at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Santiago rather than in Santiago. We may find you even better rates, too.
How do I find the best Santiago hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Santiago then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Santiago?
The cheapest hotel in Santiago is $75. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Santiago?
There are 12 hotels in Santiago on Travelocity.
What are the best hotels in Santiago?
Santiago has so many great hotels to choose from at Travelocity --- and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Santiago for you!
When is the best time to visit Santiago?
If you want the joy of a fun-filled trip in peak season, visit Santiago during October, November and December. If you'd prefer the peace of off-season, book a stay during quieter months, such as May, July and September.
When is the cheapest time to stay in Santiago?
Based on historic data is usually the cheapest month to visit Santiago. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Santiago?
There are multiple hotels in Santiago that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Santiago. We have plenty of kid-friendly hotels in Santiago to choose from on Travelocity!
Why book a hotel in Santiago through Travelocity?
Because we have the top hotels in Santiago! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Santiago on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Santiago hotel reviews by fellow wanderers

HOTEL VISTA LAGO

HOTEL VISTA LAGO

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Very clean, food was 10/10 "
A verified traveler stayed at HOTEL VISTA LAGO
HOTEL VISTA LAGO
Explore More Ways to Travel with Travelocity

Explore More Ways to Travel with Travelocity