
$279 Cheap American Airlines flights from Minneapolis to Lexington (MSP to LEX)
Find The Best Day To Fly from Minneapolis to Lexington
Amazing American Airlines MSP to LEX Flight Deals
The cheapest flights to Blue Grass found within the past 7 days were $397 round trip and $279 one way. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover our best American Airlines flight from Minneapolis MSP to Lexington LEX
To find the best deals on flights to Minneapolis from Lexington with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.
Return flights from Minneapolis MSP to Lexington LEX with American Airlines
If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $397 to $405, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply.
Book one-way American Airlines flights from Minneapolis MSP to Lexington LEX
A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Minneapolis to Lexington costs from $279. Prices and availability subject to change. Additional terms may apply.
The easy way to find cheap flights to Lexington LEX from Minneapolis MSP with American Airlines
To find a cheap American Airlines flight from Minneapolis MSP to Lexington LEX, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference.
How to find our best airfare deals on American Airlines flights from Minneapolis MSP to Lexington LEX
If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as November, or if you book a flight with a stopover.
Find nonstop flights from Minneapolis MSP to Lexington LEX with American Airlines
If you’re keen to be on Lexington soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it.
Flexible airline tickets for American Airlines flights from Minneapolis MSP to Lexington LEX
Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.
There are a lot of reasons to book your flights to Lexington LEX from Minneapolis MSP with American Airlines on Travelocity
At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.
Travelers ❤️ these 🏨 after their flight to Lexington

Reviewed on May 5, 2025

Reviewed on Apr 29, 2025

Reviewed on May 10, 2025
Popular American Airlines Flight Routes from MSP
- American Airlines MSP to ORD
- American Airlines MSP to MIA
- American Airlines MSP to DUB
- American Airlines MSP to DTW
- American Airlines MSP to ATL
- American Airlines MSP to MCO
- American Airlines MSP to SEA
- American Airlines MSP to TPA
- American Airlines MSP to CUN
- American Airlines MSP to JFK
- American Airlines MSP to DFW
Top American Airlines Flight Routes from LEX
Top Flights for American Airlines originating from MSP
Domestic
- San Juan to Orlando (SJU - MCO)
- Orlando to San Juan (MCO - SJU)
- Atlanta to Las Vegas (ATL - LAS)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- New York to Santiago (JFK - STI)
- Philadelphia to Orlando (PHL - MCO)
- New York to Orlando (LGA - MCO)
- New York to Orlando (LGA - MCO)
- Atlanta to Las Vegas (ATL - LAS)
- New York to Las Vegas (JFK - LAS)
International
- Newark Liberty Intl. Airport to Las Vegas (EWR - LAS)
- Los Angeles to Tokyo (LAX - HND)
- New York to Las Vegas (JFK - LAS)
- New York to Santiago (JFK - STI)
- New York to Montego Bay (JFK - MBJ)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- New York to Montego Bay (JFK - MBJ)
- Los Angeles to Tokyo (LAX - HND)
- New York to Santo Domingo (JFK - SDQ)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)