American Airlines Flight 4500 Deals & Information (2026/2027)

Wander Wisely with exceptional service, 24/7 supportOpens in a new window

Feel at ease with free flight cancellations within 24 hours of booking

Change your flight without a fee on select flights

American Airlines Flight 4500 Route Deals From $122

The cheapest prices found with in the last 7 days for return flights were $286 and $122 for one-way flights to Lambert-St. Louis Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Feb 2 - Thu, Feb 5
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$286 Roundtrip, found 4 days ago
$286
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, Feb 2 from Logan Intl. to Lambert-St. Louis Intl., returning Thu, Feb 5, priced at $286 found 4 days ago
Mon, Mar 16 - Tue, Mar 17
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$294 Roundtrip, found 6 days ago
$294
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Mar 16 from Logan Intl. to Lambert-St. Louis Intl., returning Tue, Mar 17, priced at $294 found 6 days ago
Wed, May 6 - Sat, May 9
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$301 Roundtrip, found 2 days ago
$301
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, May 6 from Logan Intl. to Lambert-St. Louis Intl., returning Sat, May 9, priced at $301 found 2 days ago
Mon, Feb 2 - Thu, Feb 5
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$302 Roundtrip, found 4 days ago
$302
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, Feb 2 from Logan Intl. to Lambert-St. Louis Intl., returning Thu, Feb 5, priced at $302 found 4 days ago
Sat, Apr 11 - Mon, Apr 13
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$308 Roundtrip, found 3 days ago
$308
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Apr 11 from Logan Intl. to Lambert-St. Louis Intl., returning Mon, Apr 13, priced at $308 found 3 days ago
Thu, Feb 5 - Mon, Feb 9
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$310 Roundtrip, found 5 days ago
$310
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, Feb 5 from Logan Intl. to Lambert-St. Louis Intl., returning Mon, Feb 9, priced at $310 found 5 days ago
Mon, Feb 2 - Thu, Feb 5
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$313 Roundtrip, found 4 days ago
$313
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, Feb 2 from Logan Intl. to Lambert-St. Louis Intl., returning Thu, Feb 5, priced at $313 found 4 days ago
Sat, Feb 14 - Mon, Feb 16
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$316 Roundtrip, found 3 days ago
$316
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Feb 14 from Logan Intl. to Lambert-St. Louis Intl., returning Mon, Feb 16, priced at $316 found 3 days ago
Mon, Feb 2 - Thu, Feb 5
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$318 Roundtrip, found 4 days ago
$318
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, Feb 2 from Logan Intl. to Lambert-St. Louis Intl., returning Thu, Feb 5, priced at $318 found 4 days ago
Sat, Feb 14 - Mon, Feb 16
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$326 Roundtrip, found 3 days ago
$326
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Feb 14 from Logan Intl. to Lambert-St. Louis Intl., returning Mon, Feb 16, priced at $326 found 3 days ago
Sat, Apr 11 - Wed, Apr 15
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$345 Roundtrip, found 19 hours ago
$345
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Sat, Apr 11 from Logan Intl. to Lambert-St. Louis Intl., returning Wed, Apr 15, priced at $345 found 19 hours ago

Frequently asked questions

What route does flight number AA4500 take?
AA4500 takes several routes. The most frequently flown is between Indianapolis, IN Airport (IND-Indianapolis Intl.) and Charlotte-Douglas Intl. Airport (CLT), which flies direct. This service takes roughly 1 hour and 48 minutes. However, you might find other flights with this number that have one or more stops.
What kind of plane is on flight number AA4500?
It's likely you'll be traveling aboard an Embraer 175 if you're taking flight AA4500 from Indianapolis Intl. Airport (IND) to CLT. This is the most commonly used aircraft on this particular route.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4500 flight with Travelocity, please visit our Customer Service Portal.