American Airlines Flight 4500 Deals & Information (2025/2026)

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American Airlines Flight 4500 Route Deals From $144

The cheapest prices found with in the last 7 days for return flights were $288 and $144 for one-way flights to Lambert-St. Louis Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Feb 28 - Wed, Mar 4
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$288 Roundtrip, found 1 day ago
$288
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Feb 28 from Logan Intl. to Lambert-St. Louis Intl., returning Wed, Mar 4, priced at $288 found 1 day ago
Thu, Feb 26 - Mon, Mar 2
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$297 Roundtrip, found 1 day ago
$297
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Feb 26 from Logan Intl. to Lambert-St. Louis Intl., returning Mon, Mar 2, priced at $297 found 1 day ago
Wed, Jan 14 - Sun, Jan 18
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$301 Roundtrip, found 5 hours ago
$301
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Wed, Jan 14 from Logan Intl. to Lambert-St. Louis Intl., returning Sun, Jan 18, priced at $301 found 5 hours ago
Tue, Jan 27 - Thu, Jan 29
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$307 Roundtrip, found 2 days ago
$307
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Jan 27 from Logan Intl. to Lambert-St. Louis Intl., returning Thu, Jan 29, priced at $307 found 2 days ago
Wed, Jan 14 - Sun, Jan 18
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$315 Roundtrip, found 5 hours ago
$315
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Wed, Jan 14 from Logan Intl. to Lambert-St. Louis Intl., returning Sun, Jan 18, priced at $315 found 5 hours ago
Wed, Dec 31 - Thu, Jan 1
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$315 Roundtrip, found 3 days ago
$315
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Dec 31 from Logan Intl. to Lambert-St. Louis Intl., returning Thu, Jan 1, priced at $315 found 3 days ago
Sat, Jan 17 - Wed, Jan 21
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$316 Roundtrip, found 5 hours ago
$316
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sat, Jan 17 from Logan Intl. to Lambert-St. Louis Intl., returning Wed, Jan 21, priced at $316 found 5 hours ago
Sat, Feb 28 - Wed, Mar 4
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$325 Roundtrip, found 1 day ago
$325
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Feb 28 from Logan Intl. to Lambert-St. Louis Intl., returning Wed, Mar 4, priced at $325 found 1 day ago
Sat, Jan 17 - Wed, Jan 21
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$329 Roundtrip, found 5 hours ago
$329
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sat, Jan 17 from Logan Intl. to Lambert-St. Louis Intl., returning Wed, Jan 21, priced at $329 found 5 hours ago
Tue, Jan 27 - Thu, Jan 29
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$337 Roundtrip, found 2 days ago
$337
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Jan 27 from Logan Intl. to Lambert-St. Louis Intl., returning Thu, Jan 29, priced at $337 found 2 days ago

Frequently asked questions

What route does flight number AA4500 take?
AA4500 takes several routes. The most frequently flown is between Indianapolis, IN Airport (IND-Indianapolis Intl.) and Charlotte-Douglas Intl. Airport (CLT), which flies direct. This service takes roughly 1 hour and 48 minutes. However, you might find other flights with this number that have one or more stops.
What kind of plane is on flight number AA4500?
It's likely you'll be traveling aboard an Embraer 175 if you're taking flight AA4500 from Indianapolis Intl. Airport (IND) to CLT. This is the most commonly used aircraft on this particular route.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4500 flight with Travelocity, please visit our Customer Service Portal.