American Airlines Flight 4500 Deals & Information (2025/2026)

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American Airlines Flight 4500 Route Deals From $163

The cheapest prices found with in the last 7 days for return flights were $318 and $163 for one-way flights to Lambert-St. Louis Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Dec 16 - Thu, Dec 18
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$318 Roundtrip, found 6 days ago
$318
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Dec 16 from Logan Intl. to Lambert-St. Louis Intl., returning Thu, Dec 18, priced at $318 found 6 days ago
Fri, Jan 9 - Wed, Jan 14
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$360 Roundtrip, found 20 hours ago
$360
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Fri, Jan 9 from Logan Intl. to Lambert-St. Louis Intl., returning Wed, Jan 14, priced at $360 found 20 hours ago
Wed, Dec 31 - Thu, Jan 1
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$367 Roundtrip, found 13 hours ago
$367
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Dec 31 from Logan Intl. to Lambert-St. Louis Intl., returning Thu, Jan 1, priced at $367 found 13 hours ago
Fri, Jan 9 - Wed, Jan 14
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$376 Roundtrip, found 20 hours ago
$376
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Fri, Jan 9 from Logan Intl. to Lambert-St. Louis Intl., returning Wed, Jan 14, priced at $376 found 20 hours ago
Fri, Jan 9 - Wed, Jan 14
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$380 Roundtrip, found 20 hours ago
$380
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Fri, Jan 9 from Logan Intl. to Lambert-St. Louis Intl., returning Wed, Jan 14, priced at $380 found 20 hours ago
Sat, May 23 - Tue, May 26
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$441 Roundtrip, found 3 hours ago
$441
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Sat, May 23 from Logan Intl. to Lambert-St. Louis Intl., returning Tue, May 26, priced at $441 found 3 hours ago
Sat, May 23 - Tue, May 26
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$451 Roundtrip, found 3 hours ago
$451
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Sat, May 23 from Logan Intl. to Lambert-St. Louis Intl., returning Tue, May 26, priced at $451 found 3 hours ago

Frequently asked questions

What route does flight number AA4500 take?
AA4500 takes several routes. The most frequently flown is between Indianapolis, IN Airport (IND-Indianapolis Intl.) and Charlotte-Douglas Intl. Airport (CLT), which flies direct. This service takes roughly 1 hour and 48 minutes. However, you might find other flights with this number that have one or more stops.
What kind of plane is on flight number AA4500?
It's likely you'll be traveling aboard an Embraer 175 if you're taking flight AA4500 from Indianapolis Intl. Airport (IND) to CLT. This is the most commonly used aircraft on this particular route.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4500 flight with Travelocity, please visit our Customer Service Portal.