Search Panama City luxury spa hotels
Our top choices for a great stay
Sofitel Legend Casco Viejo, Panama City
$293 nightly
The price is $322 total per night from Jul 13 to Jul 14
$322 total
Jul 13 - Jul 14
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (669 reviews)
Hotel La Compañía Casco Antiguo
$259 nightly
The price is $285 total per night from Jul 6 to Jul 7
$285 total
Jul 6 - Jul 7
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 5 restaurants. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (310 reviews)
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
$269 nightly
The price is $296 total per night from Jul 2 to Jul 3
$296 total
Jul 2 - Jul 3
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (703 reviews)
Hyatt Regency Panama City
$214 nightly
The price is $235 total per night from Jun 28 to Jun 29
$235 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and 2 restaurants. Popular attractions Albrook Shopping Mall and Via Espana ...
9.6/10 Exceptional! (344 reviews)
Bristol Panama, a Registry Collection Hotel
$225 nightly
The price is $247 total per night from Jul 17 to Jul 18
$247 total
Jul 17 - Jul 18
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,000 reviews)
Hilton Panama
$253 nightly
The price is $278 total per night from Jun 27 to Jun 28
$278 total
Jun 27 - Jun 28
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy a full-service spa, 4 restaurants, and an attached winery. Our guests praise the helpful staff in our ...
9/10 Wonderful! (1,001 reviews)
Waldorf Astoria Panama
$275 nightly
The price is $303 total per night from Jun 26 to Jun 27
$303 total
Jun 26 - Jun 27
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,000 reviews)
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
$165 nightly
The price is $182 total per night from Jun 20 to Jun 21
$182 total
Jun 20 - Jun 21
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and a casino. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,002 reviews)
Megapolis Hotel Panamá
$131 nightly
The price is $145 total per night from Jul 19 to Jul 20
$145 total
Jul 19 - Jul 20
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.4/10 Very Good! (1,573 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
