Search Panama City luxury spa hotels
Our top choices for a great stay
Sofitel Legend Casco Viejo, Panama City
$366 nightly
The price is $402 total per night from Apr 10 to Apr 11
$402 total
Apr 10 - Apr 11
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (612 reviews)
Hotel La Compañía Casco Antiguo
$354 nightly
The price is $390 total per night from Apr 7 to Apr 8
$390 total
Apr 7 - Apr 8
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 5 restaurants. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (282 reviews)
Hyatt Regency Panama City
$164 nightly
The price is $181 total per night from Mar 27 to Mar 28
$181 total
Mar 27 - Mar 28
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Popular attractions Via Espana and Avenida Balboa ...
9.8/10 Exceptional! (217 reviews)
Bristol Panama, a Registry Collection Hotel
$182 nightly
The price is $200 total per night from Apr 13 to Apr 14
$200 total
Apr 13 - Apr 14
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,003 reviews)
Waldorf Astoria Panama
$286 nightly
The price is $315 total per night from Apr 6 to Apr 7
$315 total
Apr 6 - Apr 7
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,001 reviews)
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
$159 nightly
The price is $175 total per night from Mar 28 to Mar 29
$175 total
Mar 28 - Mar 29
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and a casino. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,002 reviews)
Megapolis Hotel Panamá
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.4/10 Very Good! (1,453 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
