Search Panama City luxury spa hotels
Our top choices for a great stay
Hyatt Regency Panama City
$149 nightly
The price is $164 total per night from Nov 14 to Nov 15
$164 total
Nov 14 - Nov 15
Total with taxes and fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Popular attractions Albrook Shopping Mall and ...
10/10 Exceptional! (92 reviews)
Sofitel Legend Casco Viejo, Panama City
$293 nightly
The price is $322 total per night from Dec 9 to Dec 10
$322 total
Dec 9 - Dec 10
Total with taxes and fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (524 reviews)
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
$179 nightly
The price is $197 total per night from Dec 6 to Dec 7
$197 total
Dec 6 - Dec 7
Total with taxes and fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (622 reviews)
Hotel La Compañía Casco Antiguo
$310 nightly
The price is $341 total per night from Nov 25 to Nov 26
$341 total
Nov 25 - Nov 26
Total with taxes and fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 5 restaurants. Our guests praise the helpful staff and the property ...
9.6/10 Exceptional! (243 reviews)
Bristol Panama, a Registry Collection Hotel
$176 nightly
The price is $193 total per night from Dec 6 to Dec 7
$193 total
Dec 6 - Dec 7
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff and the property ...
9.2/10 Wonderful! (1,003 reviews)
Hilton Panama
$178 nightly
The price is $195 total per night from Dec 7 to Dec 8
$195 total
Dec 7 - Dec 8
Total with taxes and fees
Stay at this 5-star luxury hotel in Panama City. Enjoy a full-service spa, 4 restaurants, and an attached winery. Our guests praise the helpful staff in our ...
8.8/10 Excellent! (1,005 reviews)
Waldorf Astoria Panama
$171 nightly
The price is $189 total per night from Dec 6 to Dec 7
$189 total
Dec 6 - Dec 7
Total with taxes and fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,002 reviews)
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
$159 nightly
The price is $175 total per night from Nov 15 to Nov 16
$175 total
Nov 15 - Nov 16
Total with taxes and fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and a casino. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,000 reviews)
Megapolis Hotel Panamá
$122 nightly
The price is $135 total per night from Nov 15 to Nov 16
$135 total
Nov 15 - Nov 16
Total with taxes and fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.4/10 Very Good! (1,180 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
