Search Panama City luxury spa hotels
Our top choices for a great stay
Hyatt Regency Panama City
$143 nightly
The price is $158 total per night from Jul 5 to Jul 6
$158 total
Jul 5 - Jul 6
Total includes taxes and fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Popular attractions Albrook Shopping Mall and ...
10/10 Exceptional! (22 reviews)
Sofitel Legend Casco Viejo, Panama City
$293 nightly
The price is $322 total per night from Jul 16 to Jul 17
$322 total
Jul 16 - Jul 17
Total includes taxes and fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (471 reviews)
Hotel La Compania, in the Unbound Collection by Hyatt
$350 nightly
The price is $385 total per night from Jul 6 to Jul 7
$385 total
Jul 6 - Jul 7
Total includes taxes and fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 5 restaurants. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (217 reviews)
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
$204 nightly
The price is $225 total per night from Aug 1 to Aug 2
$225 total
Aug 1 - Aug 2
Total includes taxes and fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (583 reviews)
Bristol Panama, a Registry Collection Hotel
$165 nightly
The price is $182 total per night from Aug 2 to Aug 3
$182 total
Aug 2 - Aug 3
Total includes taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff and the property ...
9.2/10 Wonderful! (1,008 reviews)
Hilton Panama
$195 nightly
The price is $214 total per night from Aug 1 to Aug 2
$214 total
Aug 1 - Aug 2
Total includes taxes and fees
Stay at this 5-star luxury hotel in Panama City. Enjoy a full-service spa, 4 restaurants, and an attached winery. Our guests praise the helpful staff in our ...
8.8/10 Excellent! (1,004 reviews)
Waldorf Astoria Panama
$206 nightly
The price is $227 total per night from Jul 18 to Jul 19
$227 total
Jul 18 - Jul 19
Total includes taxes and fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,002 reviews)
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
$159 nightly
The price is $175 total per night from Jul 12 to Jul 13
$175 total
Jul 12 - Jul 13
Total includes taxes and fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and a casino. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (964 reviews)
Megapolis Hotel Panamá
$125 nightly
The price is $138 total per night from Jul 18 to Jul 19
$138 total
Jul 18 - Jul 19
Total includes taxes and fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.2/10 Very Good! (932 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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