Search Panama City luxury spa hotels
Our top choices for a great stay
Hyatt Regency Panama City
$151 nightly
The price is $166 total per night from Sep 14 to Sep 15
$166 total
Sep 14 - Sep 15
Total with taxes and fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Popular attractions Albrook Shopping Mall and ...
10/10 Exceptional! (58 reviews)
Sofitel Legend Casco Viejo, Panama City
$293 nightly
The price is $322 total per night from Sep 3 to Sep 4
$322 total
Sep 3 - Sep 4
Total with taxes and fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (491 reviews)
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
$221 nightly
The price is $243 total per night from Sep 14 to Sep 15
$243 total
Sep 14 - Sep 15
Total with taxes and fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (599 reviews)
Hotel La Compania, in the Unbound Collection by Hyatt
$263 nightly
The price is $290 total per night from Sep 1 to Sep 2
$290 total
Sep 1 - Sep 2
Total with taxes and fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 5 restaurants. Our guests praise the helpful staff and the property ...
9.6/10 Exceptional! (228 reviews)
Bristol Panama, a Registry Collection Hotel
$218 nightly
The price is $240 total per night from Sep 22 to Sep 23
$240 total
Sep 22 - Sep 23
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff and the property ...
9.2/10 Wonderful! (1,000 reviews)
Hilton Panama
$212 nightly
The price is $233 total per night from Sep 20 to Sep 21
$233 total
Sep 20 - Sep 21
Total with taxes and fees
Stay at this 5-star luxury hotel in Panama City. Enjoy a full-service spa, 4 restaurants, and an attached winery. Our guests praise the helpful staff in our ...
8.8/10 Excellent! (1,001 reviews)
Waldorf Astoria Panama
$220 nightly
The price is $242 total per night from Sep 20 to Sep 21
$242 total
Sep 20 - Sep 21
Total with taxes and fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,001 reviews)
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
$159 nightly
The price is $175 total per night from Aug 30 to Aug 31
$175 total
Aug 30 - Aug 31
Total with taxes and fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and a casino. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (984 reviews)
Megapolis Hotel Panamá
$125 nightly
The price is $138 total per night from Sep 20 to Sep 21
$138 total
Sep 20 - Sep 21
Total with taxes and fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.4/10 Very Good! (1,041 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.