Search Panama City luxury spa hotels
Our top choices for a great stay
Sofitel Legend Casco Viejo, Panama City
$302 nightly
The price is $332 total per night from Jun 4 to Jun 5
$332 total
Jun 4 - Jun 5
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (645 reviews)
Hotel La Compañía Casco Antiguo
$310 nightly
The price is $341 total per night from Jun 1 to Jun 2
$341 total
Jun 1 - Jun 2
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 5 restaurants. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (296 reviews)
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
$247 nightly
The price is $271 total per night from May 15 to May 16
$271 total
May 15 - May 16
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (691 reviews)
Hyatt Regency Panama City
$161 nightly
The price is $177 total per night from May 31 to Jun 1
$177 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and 2 restaurants. Popular attractions Albrook Shopping Mall and Via Espana ...
9.6/10 Exceptional! (291 reviews)
Bristol Panama, a Registry Collection Hotel
$183 nightly
The price is $201 total per night from May 7 to May 8
$201 total
May 7 - May 8
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,005 reviews)
Hilton Panama
$237 nightly
The price is $261 total per night from May 31 to Jun 1
$261 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy a full-service spa, 4 restaurants, and an attached winery. Our guests praise the helpful staff in our ...
9/10 Wonderful! (1,001 reviews)
Waldorf Astoria Panama
$271 nightly
The price is $298 total per night from May 31 to Jun 1
$298 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,002 reviews)
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
$159 nightly
The price is $175 total per night from May 9 to May 10
$175 total
May 9 - May 10
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and a casino. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,001 reviews)
Megapolis Hotel Panamá
$189 nightly
The price is $210 total per night from May 5 to May 6
$210 total
May 5 - May 6
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.4/10 Very Good! (1,522 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
