Search Panama City luxury spa hotels
Our top choices for a great stay
Sofitel Legend Casco Viejo, Panama City
$327 nightly
The price is $360 total per night from Feb 1 to Feb 2
$360 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (572 reviews)
Hyatt Regency Panama City
$164 nightly
The price is $181 total per night from Feb 7 to Feb 8
$181 total
Feb 7 - Feb 8
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Popular attractions Albrook Shopping Mall and Avenida ...
9.8/10 Exceptional! (167 reviews)
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
$262 nightly
The price is $288 total per night from Feb 6 to Feb 7
$288 total
Feb 6 - Feb 7
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (652 reviews)
Hotel La Compañía Casco Antiguo
$404 nightly
The price is $444 total per night from Feb 1 to Feb 2
$444 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 5 restaurants. Our guests praise the helpful staff and the property ...
9.6/10 Exceptional! (261 reviews)
Bristol Panama, a Registry Collection Hotel
$197 nightly
The price is $217 total per night from Feb 16 to Feb 17
$217 total
Feb 16 - Feb 17
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,003 reviews)
Hilton Panama
$206 nightly
The price is $227 total per night from Feb 15 to Feb 16
$227 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy a full-service spa, 4 restaurants, and an attached winery. Our guests praise the helpful staff in our ...
8.8/10 Excellent! (1,000 reviews)
Waldorf Astoria Panama
$221 nightly
The price is $243 total per night from Feb 6 to Feb 7
$243 total
Feb 6 - Feb 7
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,004 reviews)
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
$159 nightly
The price is $175 total per night from Feb 16 to Feb 17
$175 total
Feb 16 - Feb 17
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and a casino. Our guests praise the helpful staff and the clean rooms in ...
8.6/10 Excellent! (1,015 reviews)
Megapolis Hotel Panamá
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.4/10 Very Good! (1,367 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
