
$237 Cheap American Airlines flights from Greenville to Columbia (GSP to CAE)
Find The Best Day To Fly from Greenville to Columbia
Amazing American Airlines GSP to CAE Flight Deals
The cheapest flights to Columbia Metropolitan found within the past 7 days were round trip and $237 one way. Prices and availability subject to change. Additional terms may apply.
Travelers ❤️ these 🏨 after their flight to Columbia

Country Inn & Suites by Radisson, Columbia Airport, SC
2245 Airport Blvd, Cayce, SC
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free ...
8.2/10 Very Good! (1,002 reviews)
"close to highway and gas. big rooms and nice beds."
Reviewed on Jul 16, 2025

Motel 6 West Columbia, SC - Airport
650 Cherokee Lane, West Columbia, SC
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A picnic area, laundry facilities, and barbecue grills are also on ...
7.6/10 Good! (321 reviews)
"Great rooms this is my go to for the area after one stay."
Reviewed on Jul 12, 2025

Sleep Inn Airport
2208 A Edmund Hwy, West Columbia, SC
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
7.6/10 Good! (782 reviews)
"Tracy at the front desk was nice as well as the gentleman at night"
Reviewed on Jul 9, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular American Airlines Flight Routes from GSP
Top American Airlines Flight Routes from CAE
Top Flights for American Airlines originating from GSP
Domestic
- Philadelphia to Orlando (PHL - MCO)
- New York to Orlando (JFK - MCO)
- Los Angeles to Honolulu (LAX - HNL)
- Los Angeles to San Salvador (LAX - SAL)
- New York to Montego Bay (JFK - MBJ)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Newark Liberty Intl. Airport to Las Vegas (EWR - LAS)
- Boston to Orlando (BOS - MCO)
- Los Angeles to Honolulu (LAX - HNL)
- Philadelphia to Orlando (PHL - MCO)
International
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- New York to Montego Bay (JFK - MBJ)
- Philadelphia to San Juan (PHL - SJU)
- Orlando to San Juan (MCO - SJU)
- Philadelphia to Orlando (PHL - MCO)
- San Juan to Orlando (SJU - MCO)
- New York to Santiago (JFK - STI)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- Philadelphia to San Juan (PHL - SJU)
- New York to Santiago (JFK - STI)
Most Popular
Flights
- San Diego to Charleston (SAN - CHS)
- Charleston to Atlanta (CHS - ATL)
- Atlanta to Charleston (ATL - CHS)
- Charleston to New York (CHS - JFK)
- Boston to Myrtle Beach (BOS - MYR)
- Detroit to Charleston (DTW - CHS)
- Hartford to Myrtle Beach (BDL - MYR)
- Atlanta to Myrtle Beach (ATL - MYR)
- New York to Charleston (JFK - CHS)
- Newark Liberty Intl. Airport to Myrtle Beach (EWR - MYR)
- Charleston to Philadelphia (CHS - PHL)
- Chicago to Myrtle Beach (ORD - MYR)
- American Airlines New York (JFK) to Myrtle Beach (MYR) flights
- Baltimore to Myrtle Beach (BWI - MYR)
- Cleveland to Myrtle Beach (CLE - MYR)
- JetBlue Airways North Charleston (CHS) to Boston (BOS) flights
- Charleston to Miami (CHS - MIA)
- Chicago to Charleston (ORD - CHS)
- Syracuse to Myrtle Beach (SYR - MYR)
- Pittsburgh to Myrtle Beach (PIT - MYR)
- JetBlue Airways Boston (BOS) to North Charleston (CHS) flights
- JetBlue Airways Tampa (TPA) to North Charleston (CHS) flights
- Philadelphia to Charleston (PHL - CHS)
- Greenville to Orlando (GSP - MCO)
- Detroit to Myrtle Beach (DTW - MYR)
- Charlotte to Myrtle Beach (CLT - MYR)
- Philadelphia to Myrtle Beach (PHL - MYR)
- Charleston to Orlando (CHS - MCO)
- Greenville to Nashville (GSP - BNA)
- Greenville to Dallas (GSP - DFW)