Book Hotels in Worthington, MO
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Top Worthington hotels

Country Cabin In The Woods
Kirksville
This cabin featured laundry facilities and barbecue grills.
"The cabin was a great get away from the town. Very remote and peaceful cabin. Very clean. Could have used some brighter lighting. It was difficult to play games at the kitchen table after sunset. Thank you!!!"
Reviewed on Jul 13, 2025

Holiday Inn Express & Suites Kirksville - University Area by IHG
2523 South Franklin St., Kirksville, MO
Fully refundable
$127 nightly
The price is $144 total per night from Sep 28 to Sep 29
$144 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Amazing Hotel!
"The service desk guy was friendly and accommodating. The room was nice, beds slept well. The pool chemical was off or the filter wasn't working properly. but, my grandchildren enjoyed it anyway. The breakfast was very good. It had biscuits & gravy, eggs, sausage, toast, bagels, pancakes, yogurt they ..."
Reviewed on Sep 4, 2025

Hampton Inn Kirksville
2604 N. Baltimore Street, Kirksville, MO
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $155 total per night from Oct 2 to Oct 3
$155 total
Oct 2 - Oct 3
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Clean hotel with friendly staff."
Reviewed on Sep 21, 2025

Super 8 by Wyndham Kirksville-University Area
1101 Country Club Dr, Kirksville, MO
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $73 total per night from Sep 28 to Sep 29
$73 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free parking. Guests will appreciate freebies like buffet breakfast and free self parking. ...
"The room was nice and clean. The housekeeping staff was very polite. There is no elevator and I was put on the 3rd floor and I am over 60 years old so it was a lot of stairs for someone my age. I have no idea how someone older or handicapped would access the upper floors with no elevator but overall ..."
Reviewed on Sep 18, 2025

Baymont by Wyndham Kirksville University Area
2702 South Franklin, Kirksville, MO
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $72 total per night from Oct 19 to Oct 20
$72 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
"Breakfast was great"
Reviewed on Sep 18, 2025

Quality Inn Kirksville
2209 N Baltimore St, Kirksville, MO
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $81 total per night from Sep 28 to Sep 29
$81 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the 24-hour business center. ...
"This hotel was a great fit but I will not use Expedia anymore! We had to pay extra fees when we arrived that Expedia charged!"
Reviewed on Aug 3, 2025

Knights Inn Kirksville
2521 South Franklin Street, Kirksville, MO
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $76 total per night from Sep 28 to Sep 29
$76 total
Sep 28 - Sep 29
Total with taxes and fees
Free WiFi in public areas is available at this motel. Take advantage of the free self parking.
"Rooms are dated but roomy and clean. Staff friendly. Price good for what it was"
Reviewed on May 18, 2025

Days Inn by Wyndham Kirksville
3805 S Baltimore St, Kirksville, MO
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $64 total per night from Sep 28 to Sep 29
$64 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel features an indoor pool and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Needs pest control because the hotel has roaches"
Reviewed on Aug 15, 2025

Zeke’s Retreat – Hunter’s Getaway with On-Site Taxidermy Shop
Greencastle
$210 nightly
The price is $210 total per night from Sep 29 to Sep 30
$210 total
Sep 29 - Sep 30
Total with taxes and fees
Stay at this vacation home in Adair County. Enjoy air conditioning.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Worthington hotel reviews by fellow wanderers

Hampton Inn Kirksville
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Clean hotel with friendly staff. "
A verified traveler stayed at Hampton Inn Kirksville
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