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Top Santiago Sur hotels
Hotel Santa Catalina Panama
Calle hacia el Estero Hicaco Veraguas
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $142 total per night from Jul 17 to Jul 18
$142 total
Jul 17 - Jul 18
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Relax with a drink at the poolside bar and enjoy perks like free self parking and free WiFi. ...
"Staff was great! Food was delicious! Clean property."
Reviewed on May 28, 2026
Hotel Plaza Los Tucanes
Vía interamericana Nuevo Santiago Provincia de Veraguas
Fully refundableReserve now, pay when you stay
$46 nightly
The price is $51 total per night from Jul 21 to Jul 22
$51 total
Jul 21 - Jul 22
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free cooked-to-order breakfast, free WiFi, and free self parking. Business travelers can take advantage ...
"👌"
Reviewed on Jul 12, 2026
Hotel Mykonos Panama
Panamerican Highway Nuevo Santiago Veraguas
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $90 total per night from Jul 28 to Jul 29
$90 total
Jul 28 - Jul 29
Total with taxes and fees
This smoke-free hotel features a full-service spa, 3 outdoor pools, and a restaurant. There's fun for all ages with a children's pool and a playground, and families ...
"Excelente hotel . Muy amable el personal. Buena situación. Todo limpio. Las camas muy buenas. Todo bien"
Reviewed on Jul 12, 2026
Hotel Gran David
Vía Interamericana Santiago Veraguas
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $63 total per night from Jul 26 to Jul 27
$63 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Relax with a drink at the bar/lounge and enjoy free perks like cooked-to-order breakfast ...
"Hotel muy bonito, el personal muy amable, solo reporte que uno de los focos del baño no estaba funcionando y fueron a realizar las correcciones, el hotel cuenta con un restaurante muy bueno, área de piscina y un bar restaurante muy bueno también, definitivamente volveré."
Reviewed on Jul 12, 2026
Hotel y Restaurante Mama Ines
Calle Hacia Playa Estero Hicaco Veraguas Province
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $72 total per night from Jul 28 to Jul 29
$72 total
Jul 28 - Jul 29
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Relax with a drink at the poolside bar and enjoy free perks like cooked-to-order breakfast ...
"We enjoyed the stay. I would stay there again"
Reviewed on Jun 29, 2026
Hotel Galería
Vía Interamericana Santiago, Km 232.88 Nuevo Santiago
This traditional hotel features 2 outdoor pools, a gym, and a restaurant. Traveling on business? Take advantage of the 3 conference rooms, along with free WiFi ...
"Hay un restaurante en el hotel con desayuno y comida económica y muy sabrosa. La ubicación del hotel es muy céntrica. Es seguro. Tiene centro comercial al lado. Parqueo de carro seguro. Es perfecto para una visita a Santiago."
Reviewed on Apr 15, 2026
Cabañas Palma Real
Las Colomas, Santiago Sur via principal Santiago Sur Provincia de Veraguas
$68 nightly
The price is $75 total per night from Jul 17 to Jul 18
$75 total
Jul 17 - Jul 18
Total with taxes and fees
An outdoor pool, free self parking, and barbecue grills are featured at this cabin. WiFi in public areas is free. A terrace and a garden are also provided.
Bambuda Santa Catalina
Finca 464377 Hicaco Veraguas
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $116 total per night from Jul 26 to Jul 27
$116 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...
Villa Coco
Via Catalina Farms Hicaco Veraguas
$170 nightly
The price is $187 total per night from Jul 26 to Jul 27
$187 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. There's fun for all ages with a children's pool and a playground, and barbecue grills are ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Santiago Sur hotel reviews by fellow wanderers
Casa Morrillo
5 out of 5
Posted 4 days ago
Travelocity Verified Review
"Yes, yes, yes! Absolutely adored my stay and was sad to leave."
A verified traveler stayed at Casa Morrillo
